Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313533024> ?p ?o ?g. }
- W4313533024 abstract "Abstract The stereodivergent synthesis of allene compounds bearing α,β‐adjacent central chiralities has been realized via the Pd/Cu‐catalyzed dynamic kinetic asymmetric alkylation of racemic allenylic esters. The matched reactivity of bimetallic catalytic system enables the challenging reaction of racemic aryl‐substituted allenylic acetates with sterically crowded aldimine esters smoothly under mild reaction conditions. Various chiral non‐natural amino acids bearing a terminal allenyl group are easily synthesized in high yields and with excellent diastereo‐ and enantioselectivities (up to >20 : 1 dr, >99 % ee). Importantly, all four stereoisomers of the product can be readily accessed by switching the configurations of the two chiral metal catalysts. Furthermore, the easy interconversion between the uncommon η 3 ‐butadienyl palladium intermediate featuring a weak C=C/Pd coordination bond and a stable Csp 2 −Pd bond is beneficial for the dynamic kinetic asymmetric transformation process (DyKAT)." @default.
- W4313533024 created "2023-01-06" @default.
- W4313533024 creator A5026011213 @default.
- W4313533024 creator A5036923059 @default.
- W4313533024 creator A5051565228 @default.
- W4313533024 creator A5076288007 @default.
- W4313533024 creator A5082306289 @default.
- W4313533024 creator A5091568237 @default.
- W4313533024 date "2023-01-24" @default.
- W4313533024 modified "2023-10-16" @default.
- W4313533024 title "Stereodivergent Synthesis of Allenes with α,β‐Adjacent Central Chiralities Empowered by Synergistic Pd/Cu Catalysis" @default.
- W4313533024 cites W1899103796 @default.
- W4313533024 cites W1966392014 @default.
- W4313533024 cites W1967525658 @default.
- W4313533024 cites W1974522747 @default.
- W4313533024 cites W1979306160 @default.
- W4313533024 cites W1985586902 @default.
- W4313533024 cites W1986001811 @default.
- W4313533024 cites W1988850147 @default.
- W4313533024 cites W1998761932 @default.
- W4313533024 cites W2007224999 @default.
- W4313533024 cites W2007631118 @default.
- W4313533024 cites W2007814829 @default.
- W4313533024 cites W2013760130 @default.
- W4313533024 cites W2016306827 @default.
- W4313533024 cites W2018422533 @default.
- W4313533024 cites W2019193983 @default.
- W4313533024 cites W2019237825 @default.
- W4313533024 cites W2020202168 @default.
- W4313533024 cites W2023224512 @default.
- W4313533024 cites W2024729117 @default.
- W4313533024 cites W2031192939 @default.
- W4313533024 cites W2032668817 @default.
- W4313533024 cites W2034358928 @default.
- W4313533024 cites W2035084540 @default.
- W4313533024 cites W2051972074 @default.
- W4313533024 cites W2053556296 @default.
- W4313533024 cites W2058770230 @default.
- W4313533024 cites W2059785209 @default.
- W4313533024 cites W2061896255 @default.
- W4313533024 cites W2068885975 @default.
- W4313533024 cites W2074081891 @default.
- W4313533024 cites W2074274985 @default.
- W4313533024 cites W2078073960 @default.
- W4313533024 cites W2079055375 @default.
- W4313533024 cites W2081248392 @default.
- W4313533024 cites W2083496413 @default.
- W4313533024 cites W2085922718 @default.
- W4313533024 cites W2089794429 @default.
- W4313533024 cites W2092477273 @default.
- W4313533024 cites W2094469544 @default.
- W4313533024 cites W2100455686 @default.
- W4313533024 cites W2114482015 @default.
- W4313533024 cites W2123536607 @default.
- W4313533024 cites W2140026331 @default.
- W4313533024 cites W2140889506 @default.
- W4313533024 cites W2145511858 @default.
- W4313533024 cites W2162253433 @default.
- W4313533024 cites W2165695037 @default.
- W4313533024 cites W2175817792 @default.
- W4313533024 cites W2312853724 @default.
- W4313533024 cites W2318399853 @default.
- W4313533024 cites W2333887450 @default.
- W4313533024 cites W2334495070 @default.
- W4313533024 cites W2462036339 @default.
- W4313533024 cites W2481332613 @default.
- W4313533024 cites W2517648757 @default.
- W4313533024 cites W2558819295 @default.
- W4313533024 cites W2575724262 @default.
- W4313533024 cites W2587433337 @default.
- W4313533024 cites W2604800449 @default.
- W4313533024 cites W2727812228 @default.
- W4313533024 cites W2759137215 @default.
- W4313533024 cites W2767939570 @default.
- W4313533024 cites W2782311623 @default.
- W4313533024 cites W2784276047 @default.
- W4313533024 cites W2787283739 @default.
- W4313533024 cites W2789820073 @default.
- W4313533024 cites W2793796734 @default.
- W4313533024 cites W2804741561 @default.
- W4313533024 cites W2906068960 @default.
- W4313533024 cites W2911854241 @default.
- W4313533024 cites W2915215440 @default.
- W4313533024 cites W2917613065 @default.
- W4313533024 cites W2943881282 @default.
- W4313533024 cites W2949479060 @default.
- W4313533024 cites W2949913740 @default.
- W4313533024 cites W2950501149 @default.
- W4313533024 cites W2952119814 @default.
- W4313533024 cites W2952403058 @default.
- W4313533024 cites W2952776556 @default.
- W4313533024 cites W2953105279 @default.
- W4313533024 cites W2964175616 @default.
- W4313533024 cites W2971586612 @default.
- W4313533024 cites W2991484053 @default.
- W4313533024 cites W2991927346 @default.
- W4313533024 cites W2995805280 @default.
- W4313533024 cites W3016771912 @default.
- W4313533024 cites W3036408607 @default.
- W4313533024 cites W3036776725 @default.