FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313543484> ?p ?o ?g. }

• W4313543484 endingPage "e1328" @default.
• W4313543484 startingPage "e1321" @default.
• W4313543484 abstract "Background and Objectives The EuroQol Group 5-Dimension Self-Reported Questionnaire (EQ-5D) is a well-established instrument to assess quality of life and generates generic utility values for health states reported by patients, derived from assessments by the general public. We hypothesized that language problems and other nonmotor deficits are not captured as well as motor deficits by this system. We aimed to quantify the association between disabling neurologic deficits and the EQ-5D dimension scores and the utility score in patients with ischemic stroke. Methods We used data of the Interventional Management of Stroke III trial. Missing data were imputed by multiple imputation. The association between neurologic deficits (individual NIH Stroke Scale [NIHSS] item scores) and the EQ-5D-3L (5 three-level dimension scores and utility score) at 90 days was assessed with ordinal logistic regression and Tobit regression, respectively. The explained variance of each model was estimated with Nagelkerke pseudo-R 2 or R 2 . Results In total, 525 surviving patients were included. Complete data on both the NIHSS and EQ-5D were available for 481/525 (91.6%) patients. At 90 days, 161/491 (32.8%) patients had aphasia and 226/491 (46.0%) patients had paresis of at least 1 limb. Limb paresis, facial palsy, sensory loss, and dysarthria explained most of the variance in all EQ-5D dimension scores and the utility score. In the utility score, 8.9% of the variance was explained by neglect, 10.0% by aphasia, 10.8% by hemianopia, and 17.5%–24.1% by limb paresis. Discussion The impact of neurologic deficits on the EQ-5D in patients with ischemic stroke is mostly due to limb paresis, while the EQ-5D is less sensitive to other nonmotor deficits such as hemianopia, aphasia, and neglect. This may lead to overestimation of quality of life and, consequently, underestimation of the (cost-)effectiveness of treatments and interventions. Trial Registration Information ClinicalTrials.gov. Unique identifier: NCT00359424." @default.
• W4313543484 created "2023-01-06" @default.
• W4313543484 creator A5002102186 @default.
• W4313543484 creator A5018804393 @default.
• W4313543484 creator A5026647662 @default.
• W4313543484 creator A5026921356 @default.
• W4313543484 creator A5048297907 @default.
• W4313543484 creator A5051724198 @default.
• W4313543484 creator A5079955678 @default.
• W4313543484 creator A5083232394 @default.
• W4313543484 creator A5084860153 @default.
• W4313543484 date "2023-03-28" @default.
• W4313543484 modified "2023-10-16" @default.
• W4313543484 title "Disentangling the Association Between Neurologic Deficits, Patient-Reported Impairments, and Quality of Life After Ischemic Stroke" @default.
• W4313543484 cites W1986714427 @default.
• W4313543484 cites W1992999318 @default.
• W4313543484 cites W1994222210 @default.
• W4313543484 cites W1996802760 @default.
• W4313543484 cites W2021402729 @default.
• W4313543484 cites W2021768440 @default.
• W4313543484 cites W2032869071 @default.
• W4313543484 cites W2035464802 @default.
• W4313543484 cites W2041311794 @default.
• W4313543484 cites W2052708802 @default.
• W4313543484 cites W2056580997 @default.
• W4313543484 cites W2069764182 @default.
• W4313543484 cites W2071686284 @default.
• W4313543484 cites W2080504768 @default.
• W4313543484 cites W2088922154 @default.
• W4313543484 cites W2096782143 @default.
• W4313543484 cites W2111559905 @default.
• W4313543484 cites W2122622909 @default.
• W4313543484 cites W2151207657 @default.
• W4313543484 cites W2156762019 @default.
• W4313543484 cites W2158551075 @default.
• W4313543484 cites W2162772535 @default.
• W4313543484 cites W2473786944 @default.
• W4313543484 cites W2608704330 @default.
• W4313543484 cites W2803351570 @default.
• W4313543484 cites W2903794284 @default.
• W4313543484 cites W2909622566 @default.
• W4313543484 doi "https://doi.org/10.1212/wnl.0000000000206747" @default.
• W4313543484 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36599699" @default.
• W4313543484 hasPublicationYear "2023" @default.
• W4313543484 type Work @default.
• W4313543484 citedByCount "1" @default.
• W4313543484 countsByYear W43135434842023 @default.
• W4313543484 crossrefType "journal-article" @default.
• W4313543484 hasAuthorship W4313543484A5002102186 @default.
• W4313543484 hasAuthorship W4313543484A5018804393 @default.
• W4313543484 hasAuthorship W4313543484A5026647662 @default.
• W4313543484 hasAuthorship W4313543484A5026921356 @default.
• W4313543484 hasAuthorship W4313543484A5048297907 @default.
• W4313543484 hasAuthorship W4313543484A5051724198 @default.
• W4313543484 hasAuthorship W4313543484A5079955678 @default.
• W4313543484 hasAuthorship W4313543484A5083232394 @default.
• W4313543484 hasAuthorship W4313543484A5084860153 @default.
• W4313543484 hasBestOaLocation W43135434841 @default.
• W4313543484 hasConcept C101266164 @default.
• W4313543484 hasConcept C118552586 @default.
• W4313543484 hasConcept C126322002 @default.
• W4313543484 hasConcept C127413603 @default.
• W4313543484 hasConcept C138496976 @default.
• W4313543484 hasConcept C151956035 @default.
• W4313543484 hasConcept C15744967 @default.
• W4313543484 hasConcept C159110408 @default.
• W4313543484 hasConcept C1862650 @default.
• W4313543484 hasConcept C2779422653 @default.
• W4313543484 hasConcept C2779951463 @default.
• W4313543484 hasConcept C2780645631 @default.
• W4313543484 hasConcept C71924100 @default.
• W4313543484 hasConcept C78519656 @default.
• W4313543484 hasConcept C99508421 @default.
• W4313543484 hasConceptScore W4313543484C101266164 @default.
• W4313543484 hasConceptScore W4313543484C118552586 @default.
• W4313543484 hasConceptScore W4313543484C126322002 @default.
• W4313543484 hasConceptScore W4313543484C127413603 @default.
• W4313543484 hasConceptScore W4313543484C138496976 @default.
• W4313543484 hasConceptScore W4313543484C151956035 @default.
• W4313543484 hasConceptScore W4313543484C15744967 @default.
• W4313543484 hasConceptScore W4313543484C159110408 @default.
• W4313543484 hasConceptScore W4313543484C1862650 @default.
• W4313543484 hasConceptScore W4313543484C2779422653 @default.
• W4313543484 hasConceptScore W4313543484C2779951463 @default.
• W4313543484 hasConceptScore W4313543484C2780645631 @default.
• W4313543484 hasConceptScore W4313543484C71924100 @default.
• W4313543484 hasConceptScore W4313543484C78519656 @default.
• W4313543484 hasConceptScore W4313543484C99508421 @default.
• W4313543484 hasIssue "13" @default.
• W4313543484 hasLocation W43135434841 @default.
• W4313543484 hasLocation W43135434842 @default.
• W4313543484 hasLocation W43135434843 @default.
• W4313543484 hasLocation W43135434844 @default.
• W4313543484 hasLocation W43135434845 @default.
• W4313543484 hasOpenAccess W4313543484 @default.
• W4313543484 hasPrimaryLocation W43135434841 @default.
• W4313543484 hasRelatedWork W1541259469 @default.
• W4313543484 hasRelatedWork W15708988 @default.

• next