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• W4313556472 abstract "Abstract Background: The correlation and influencing factors of preoperative anxiety, postoperative pain, and delirium in elderly patients undergoing gastrointestinal cancer surgery were explored with the Beck Anxiety Inventory (BAI) scale, 10-point Visual Analogue Scale (VAS), and Confusion Assessment Method Chinese Reversion (CAM-CR) scale. Methods: Patients aged 65 years or above were enrolled from the First Affiliated Hospital of Guangxi Medical University, from September 2019 to October 2020. A total of 120 elderly patients who underwent gastrointestinal cancer surgery under general anesthesia were collected. Perioperative anxiety, pain, and delirium were assessed with the BAI scale, VAS scale, and CAM-CR scale. The correlation and influencing factors of preoperative high anxiety, postoperative high pain, and postoperative delirium were analyzed. Results: The incidences of high anxiety on one day before surgery (day-0) and on the postoperative day (pod) 1, 3, and 7 (pod-1, pod-3, pod-7) were 19.2%, 5.8%, 9.2%, and 0.0%, respectively. The incidences of high pain on the day-0, pod-1, pod-3, pod-7 were 0.0%, 41.7%, 15.0%, 4.2%, respectively. The incidences of delirium on the day-0, pod-1, pod-3, pod-7 were 0.0%, 24.2%, 4.2%, 0.0%, respectively. There was a positive correlation between preoperative high anxiety and postoperative high pain ( P <0.001, r =0.410), and there was a positive correlation between preoperative high anxiety and postoperative delirium ( P =0.005, r =0.281), and there was a positive correlation between postoperative high pain and postoperative delirium ( P =0.017, r =0.236). The results from multiple linear regression analysis had shown that types of cancer and surgical approaches had an impact on preoperative high anxiety ( P =0.006 and P =0.021 ); preoperative high anxiety had a positive influence on postoperative high pain ( P ＜0.001); age and preoperative high anxiety had a positive impact on postoperative delirium ( P ＜0.001 and P =0.010). Conclusions: Elderly patients receiving gastrointestinal cancer surgery had high incidences of high anxiety before surgery, high pain, and delirium on postoperative day 1. Preoperative high anxiety was positively correlation with postoperative high pain and postoperative delirium; postoperative high pain was positively correlation with postoperative delirium. Types of cancer and surgical approaches were as influencing factors of preoperative high anxiety; preoperative high anxiety was an influencing factor of postoperative high pain; and age and preoperative high anxiety were influencing factors of postoperative delirium. Trial registration ChiCTR2000032008, 17/04/2020, Title: “Effects of different analgesic methods on postoperative recovery of elderly patients with digestive tract tumor”. Website: https://www.chictr.ogr.cn." @default.
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• W4313556472 date "2023-01-05" @default.
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• W4313556472 title "Correlation and Influencing Factors of Preoperative Anxiety, Postoperative Pain, and Delirium in Elderly Patients Undergoing Gastrointestinal Cancer Surgery" @default.
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• W4313556472 doi "https://doi.org/10.21203/rs.3.rs-2389140/v1" @default.
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