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- W4313559178 endingPage "1008" @default.
- W4313559178 startingPage "1008" @default.
- W4313559178 abstract "Energy homeostasis and metabolism in mammals are strongly influenced by seasonal changes. Variations in photoperiod patterns drive adaptations in body weight and adiposity, reflecting changes in the regulation of food intake and energy expenditure. Humans also show distinct patterns of energy balance depending on the season, being more susceptible to gaining weight during a specific time of the year. Changes in body weight are mainly reflected by the adipose tissue, which is a key metabolic tissue and is highly affected by circannual rhythms. Mostly, in summer-like (long-active) photoperiod, adipocytes adopt a rather anabolic profile, more predisposed to store energy, while food intake increases and energy expenditure is reduced. These metabolic adaptations involve molecular modifications, some of which have been studied during the last years and are summarized in this review. In addition, there is a bidirectional relation between obesity and the seasonal responses, with obesity disrupting some of the seasonal responses observed in healthy mammals, and altered seasonality being highly associated with increased risk of developing obesity. This suggests that changes in photoperiod produce important metabolic alterations in healthy organisms. Biological rhythms impact the regulation of metabolism to different extents, some of which are already known, but further research is needed to fully understand the relationship between energy balance and seasonality." @default.
- W4313559178 created "2023-01-06" @default.
- W4313559178 creator A5003416093 @default.
- W4313559178 creator A5041082378 @default.
- W4313559178 creator A5043302175 @default.
- W4313559178 creator A5085916236 @default.
- W4313559178 creator A5088797858 @default.
- W4313559178 date "2023-01-05" @default.
- W4313559178 modified "2023-10-18" @default.
- W4313559178 title "Photoperiodic Remodeling of Adiposity and Energy Metabolism in Non-Human Mammals" @default.
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