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- W4313559912 abstract "Diabetic retinopathy (DR) as a microangiopathy is the most common complication in patients with diabetes mellitus (DM) and remains the leading cause of blindness among adult population. DM in its complicated pathomechanism relates to chronic hyperglycemia, hypoinsulinemia, dyslipidemia and hypertension-all these components in molecular pathways maintain oxidative stress, formation of advanced glycation end-products, microvascular changes, inflammation, and retinal neurodegeneration as one of the key players in diabetes-associated retinal perturbations. In this current review, we discuss the natural history of DR with special emphasis on ongoing inflammation and the key role of vascular endothelial growth factor (VEGF). Additionally, we provide an overview of the principles of diabetic retinopathy treatments, i.e., in laser therapy, anti-VEGF and steroid options." @default.
- W4313559912 created "2023-01-06" @default.
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- W4313559912 creator A5048212793 @default.
- W4313559912 date "2023-01-05" @default.
- W4313559912 modified "2023-10-01" @default.
- W4313559912 title "The Role of Inflammation and Therapeutic Concepts in Diabetic Retinopathy—A Short Review" @default.
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- W4313559912 doi "https://doi.org/10.3390/ijms24021024" @default.
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