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- W4313561093 abstract "Polyguluronate (PG) is an acidic homopolymer of α-(1,4)-l-guluronate separated from alginate. In this study, PG was first grafted with soy protein isolate (SPI) through the Maillard reaction to obtain a new glycoprotein (SPI-PG). Then, this novel glycoprotein was used to prepare nanoparticles to encapsulate the resveratrol (RES). Our results showed that SPI-PG-RES had better pH stability, storage stability and ionic stability than SPI-RES. In vitro digestion experiments showed that the RES bioavailability of SPI-PG-RES was much higher than that of free RES and SPI-RES. Furthermore, the in vitro antioxidant capacity of SPI-PG-RES was much stronger than that of free RES and SPI-RES. In addition, SPI-PG-RES was more effective in preventing the symptoms of DSS-induced colitis than RES and SPI-RES. These results suggested that the protein nanoparticles prepared using SPI-PG were a stable and effective hydrophobic polyphenol carrier and could be applied to food-grade components in functional foods and nutritional supplements." @default.
- W4313561093 created "2023-01-06" @default.
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- W4313561093 date "2023-06-01" @default.
- W4313561093 modified "2023-10-17" @default.
- W4313561093 title "Soy protein isolate-polyguluronate nanoparticles loaded with resveratrol for effective treatment of colitis" @default.
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- W4313561093 doi "https://doi.org/10.1016/j.foodchem.2023.135418" @default.
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