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- W4313561918 endingPage "135412" @default.
- W4313561918 startingPage "135412" @default.
- W4313561918 abstract "This study aimed to investigate the metabolic and population responses of gut microbiota to resistant starch (RS3) in the presence of exogenous Lactiplantibacillus plantarum strain 84-3 (Lp84-3) in vitro and in vivo. Lp84-3 promoted acetate, propionate, and butyrate production from RS3 by gut microbiota and increased Lactobacillus and Blautia contents in vitro. Furthermore, in the presence of Lp84-3, starch granules presented a dot-by-hole fermentation pattern. Administration of Lp84-3 with RS3 increased the level of SCFA-producing Faecalibaculum, Parabacteroides, Alistipes, and Anaeroplasma in the faeces of rates, with Lactobacillus and Akkermansia representing the key genera that significantly promoted SCFAs, especially propionate and butyrate. Lp84-3 with RS3 promoted genes related to tryptophan synthase (EC 4.2.1.20) and beta-glucosidase (EC 3.2.1.21) in faecal bacteria. Our findings highlight the ability of Lp84-3 to enhance RS3 degradation, possibly by promoting SCFA-producing bacteria, and indicate that Lp84-3 could be a potential probiotic with a beneficial effect on gut microbiota." @default.
- W4313561918 created "2023-01-06" @default.
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- W4313561918 date "2023-06-01" @default.
- W4313561918 modified "2023-10-17" @default.
- W4313561918 title "Metabolism of resistant starch RS3 administered in combination with Lactiplantibacillus plantarum strain 84-3 by human gut microbiota in simulated fermentation experiments in vitro and in a rat model" @default.
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- W4313561918 doi "https://doi.org/10.1016/j.foodchem.2023.135412" @default.
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