Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313573709> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4313573709 abstract "Coxiella burnetii causes Q fever, which is found worldwide and can be acute or chronic. This case report describes a 72-year-old man whose bilateral lower limb pain revealed a paravertebral abscess at L2-L3 due to Q fever spondylodiscitis. Surgical drainage of the abscess was performed and medical treatment is ongoing. Q fever is endemic in Portugal and transmitted by inhalation of aerosols containing spores from infected animals (cattle, goats and sheep) or by ingesting cottage cheese or unpasteurized milk. It has an incubation period of 2-3 weeks and 60% of patients are asymptomatic with only 2% needing hospitalization. Primary infection can manifest in any organ and most cases are self-limiting (self-limited febrile illness, atypical pneumonia or acute hepatitis). Less than 1% of cases evolve to chronic disease, presenting as osteomyelitis or endocarditis. Chronic disease poses a diagnostic challenge and spondylodiscitis has an insidious evolution. Diagnosis requires microbiological and clinical confirmation. Serological and polymerase chain reaction tests are used for diagnosis. Acute disease is usually treated with doxycycline for 3 weeks to avoid evolution to chronic disease. Chronic disease requires 18-24 months of doxycycline with hydroxychloroquine. Acute disease can recur so follow-up is essential as chronic Q fever can result in morbidity and mortality. In Portugal Q fever is a notifiable disease due to the epidemiological risk.Coxiella burnetii spondylodiscitis is rare so clinicians should be aware of it.The diagnosis of Q fever is challenging, especially chronic disease that presents with endocarditis, osteomyelitis or spondylodiscitis.Spondylodiscitis treatment is particularly challenging and may need neurosurgical intervention." @default.
- W4313573709 created "2023-01-06" @default.
- W4313573709 creator A5012345662 @default.
- W4313573709 creator A5031734086 @default.
- W4313573709 creator A5035380301 @default.
- W4313573709 creator A5048478573 @default.
- W4313573709 date "2022-12-21" @default.
- W4313573709 modified "2023-09-30" @default.
- W4313573709 title "Q Fever Spondylodiscitis: A Rare Manifestation of a Challenging Disease" @default.
- W4313573709 cites W1965248354 @default.
- W4313573709 cites W2103451304 @default.
- W4313573709 cites W2989566393 @default.
- W4313573709 cites W3125213403 @default.
- W4313573709 doi "https://doi.org/10.12890/2022_003703" @default.
- W4313573709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36632533" @default.
- W4313573709 hasPublicationYear "2022" @default.
- W4313573709 type Work @default.
- W4313573709 citedByCount "1" @default.
- W4313573709 countsByYear W43135737092023 @default.
- W4313573709 crossrefType "journal-article" @default.
- W4313573709 hasAuthorship W4313573709A5012345662 @default.
- W4313573709 hasAuthorship W4313573709A5031734086 @default.
- W4313573709 hasAuthorship W4313573709A5035380301 @default.
- W4313573709 hasAuthorship W4313573709A5048478573 @default.
- W4313573709 hasBestOaLocation W43135737091 @default.
- W4313573709 hasConcept C126322002 @default.
- W4313573709 hasConcept C141071460 @default.
- W4313573709 hasConcept C159047783 @default.
- W4313573709 hasConcept C16005928 @default.
- W4313573709 hasConcept C187212893 @default.
- W4313573709 hasConcept C203014093 @default.
- W4313573709 hasConcept C2775872228 @default.
- W4313573709 hasConcept C2776607032 @default.
- W4313573709 hasConcept C2777692091 @default.
- W4313573709 hasConcept C2777771103 @default.
- W4313573709 hasConcept C2777914695 @default.
- W4313573709 hasConcept C2779134260 @default.
- W4313573709 hasConcept C2780551157 @default.
- W4313573709 hasConcept C2780731870 @default.
- W4313573709 hasConcept C2780767784 @default.
- W4313573709 hasConcept C2781429187 @default.
- W4313573709 hasConcept C71924100 @default.
- W4313573709 hasConceptScore W4313573709C126322002 @default.
- W4313573709 hasConceptScore W4313573709C141071460 @default.
- W4313573709 hasConceptScore W4313573709C159047783 @default.
- W4313573709 hasConceptScore W4313573709C16005928 @default.
- W4313573709 hasConceptScore W4313573709C187212893 @default.
- W4313573709 hasConceptScore W4313573709C203014093 @default.
- W4313573709 hasConceptScore W4313573709C2775872228 @default.
- W4313573709 hasConceptScore W4313573709C2776607032 @default.
- W4313573709 hasConceptScore W4313573709C2777692091 @default.
- W4313573709 hasConceptScore W4313573709C2777771103 @default.
- W4313573709 hasConceptScore W4313573709C2777914695 @default.
- W4313573709 hasConceptScore W4313573709C2779134260 @default.
- W4313573709 hasConceptScore W4313573709C2780551157 @default.
- W4313573709 hasConceptScore W4313573709C2780731870 @default.
- W4313573709 hasConceptScore W4313573709C2780767784 @default.
- W4313573709 hasConceptScore W4313573709C2781429187 @default.
- W4313573709 hasConceptScore W4313573709C71924100 @default.
- W4313573709 hasLocation W43135737091 @default.
- W4313573709 hasLocation W43135737092 @default.
- W4313573709 hasLocation W43135737093 @default.
- W4313573709 hasOpenAccess W4313573709 @default.
- W4313573709 hasPrimaryLocation W43135737091 @default.
- W4313573709 hasRelatedWork W1465100418 @default.
- W4313573709 hasRelatedWork W1572057724 @default.
- W4313573709 hasRelatedWork W2006620900 @default.
- W4313573709 hasRelatedWork W2057751552 @default.
- W4313573709 hasRelatedWork W2172014569 @default.
- W4313573709 hasRelatedWork W2339275745 @default.
- W4313573709 hasRelatedWork W3083386429 @default.
- W4313573709 hasRelatedWork W4313573709 @default.
- W4313573709 hasRelatedWork W4377287673 @default.
- W4313573709 hasRelatedWork W4385581881 @default.
- W4313573709 isParatext "false" @default.
- W4313573709 isRetracted "false" @default.
- W4313573709 workType "article" @default.