FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313574717> ?p ?o ?g. }

• W4313574717 endingPage "86" @default.
• W4313574717 startingPage "86" @default.
• W4313574717 abstract "Platelets are probably the most accessible human cells to study exocytosis by amperometry. These cell fragments accumulate biological amines, serotonin in particular, using similar if not the same mechanisms as those employed by sympathetic, serotoninergic, and histaminergic neurons. Thus, platelets have been widely recognized as a model system to study certain neurological and psychiatric diseases. Platelets release serotonin by exocytosis, a process that entails the fusion of a secretory vesicle to the plasma membrane and that can be monitored directly by classic single cell amperometry using carbon fiber electrodes. However, this is a tedious technique because any given platelet releases only 4-8 secretory δ-granules. Here, we introduce and validate a diamond-based multielectrode array (MEA) device for the high-throughput study of exocytosis by human platelets. This is probably the first reported study of human tissue using an MEA, demonstrating that they are very interesting laboratory tools to assess alterations to exocytosis in neuropsychiatric diseases. Moreover, these devices constitute a valuable platform for the rapid testing of novel drugs that act on secretory pathways in human tissues." @default.
• W4313574717 created "2023-01-06" @default.
• W4313574717 creator A5009516922 @default.
• W4313574717 creator A5009961687 @default.
• W4313574717 creator A5017792406 @default.
• W4313574717 creator A5030183385 @default.
• W4313574717 creator A5031941235 @default.
• W4313574717 creator A5050371925 @default.
• W4313574717 creator A5056190363 @default.
• W4313574717 creator A5061790195 @default.
• W4313574717 date "2023-01-04" @default.
• W4313574717 modified "2023-09-25" @default.
• W4313574717 title "Multielectrode Arrays as a Means to Study Exocytosis in Human Platelets" @default.
• W4313574717 cites W1556409661 @default.
• W4313574717 cites W158506035 @default.
• W4313574717 cites W1599906730 @default.
• W4313574717 cites W1973564368 @default.
• W4313574717 cites W1984616479 @default.
• W4313574717 cites W1998599731 @default.
• W4313574717 cites W2006178293 @default.
• W4313574717 cites W2021808024 @default.
• W4313574717 cites W2022073170 @default.
• W4313574717 cites W2059996514 @default.
• W4313574717 cites W2061597029 @default.
• W4313574717 cites W2063938988 @default.
• W4313574717 cites W2072925847 @default.
• W4313574717 cites W2079961396 @default.
• W4313574717 cites W2090385369 @default.
• W4313574717 cites W2099298311 @default.
• W4313574717 cites W2111602670 @default.
• W4313574717 cites W2118294440 @default.
• W4313574717 cites W2189121400 @default.
• W4313574717 cites W2266249040 @default.
• W4313574717 cites W2282030547 @default.
• W4313574717 cites W2402469092 @default.
• W4313574717 cites W2427683182 @default.
• W4313574717 cites W2471779620 @default.
• W4313574717 cites W2752835418 @default.
• W4313574717 cites W2898003511 @default.
• W4313574717 cites W3103946121 @default.
• W4313574717 cites W3119053323 @default.
• W4313574717 doi "https://doi.org/10.3390/bios13010086" @default.
• W4313574717 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36671921" @default.
• W4313574717 hasPublicationYear "2023" @default.
• W4313574717 type Work @default.
• W4313574717 citedByCount "0" @default.
• W4313574717 crossrefType "journal-article" @default.
• W4313574717 hasAuthorship W4313574717A5009516922 @default.
• W4313574717 hasAuthorship W4313574717A5009961687 @default.
• W4313574717 hasAuthorship W4313574717A5017792406 @default.
• W4313574717 hasAuthorship W4313574717A5030183385 @default.
• W4313574717 hasAuthorship W4313574717A5031941235 @default.
• W4313574717 hasAuthorship W4313574717A5050371925 @default.
• W4313574717 hasAuthorship W4313574717A5056190363 @default.
• W4313574717 hasAuthorship W4313574717A5061790195 @default.
• W4313574717 hasBestOaLocation W43135747171 @default.
• W4313574717 hasConcept C139369640 @default.
• W4313574717 hasConcept C147789679 @default.
• W4313574717 hasConcept C169760540 @default.
• W4313574717 hasConcept C170493617 @default.
• W4313574717 hasConcept C17525397 @default.
• W4313574717 hasConcept C175969161 @default.
• W4313574717 hasConcept C185592680 @default.
• W4313574717 hasConcept C203014093 @default.
• W4313574717 hasConcept C2775864247 @default.
• W4313574717 hasConcept C37000724 @default.
• W4313574717 hasConcept C49039625 @default.
• W4313574717 hasConcept C52859227 @default.
• W4313574717 hasConcept C55493867 @default.
• W4313574717 hasConcept C86803240 @default.
• W4313574717 hasConcept C89560881 @default.
• W4313574717 hasConcept C95444343 @default.
• W4313574717 hasConceptScore W4313574717C139369640 @default.
• W4313574717 hasConceptScore W4313574717C147789679 @default.
• W4313574717 hasConceptScore W4313574717C169760540 @default.
• W4313574717 hasConceptScore W4313574717C170493617 @default.
• W4313574717 hasConceptScore W4313574717C17525397 @default.
• W4313574717 hasConceptScore W4313574717C175969161 @default.
• W4313574717 hasConceptScore W4313574717C185592680 @default.
• W4313574717 hasConceptScore W4313574717C203014093 @default.
• W4313574717 hasConceptScore W4313574717C2775864247 @default.
• W4313574717 hasConceptScore W4313574717C37000724 @default.
• W4313574717 hasConceptScore W4313574717C49039625 @default.
• W4313574717 hasConceptScore W4313574717C52859227 @default.
• W4313574717 hasConceptScore W4313574717C55493867 @default.
• W4313574717 hasConceptScore W4313574717C86803240 @default.
• W4313574717 hasConceptScore W4313574717C89560881 @default.
• W4313574717 hasConceptScore W4313574717C95444343 @default.
• W4313574717 hasIssue "1" @default.
• W4313574717 hasLocation W43135747171 @default.
• W4313574717 hasLocation W43135747172 @default.
• W4313574717 hasLocation W43135747173 @default.
• W4313574717 hasOpenAccess W4313574717 @default.
• W4313574717 hasPrimaryLocation W43135747171 @default.
• W4313574717 hasRelatedWork W1987096130 @default.
• W4313574717 hasRelatedWork W2014900060 @default.
• W4313574717 hasRelatedWork W2041159220 @default.
• W4313574717 hasRelatedWork W2049751046 @default.

• next