Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313584518> ?p ?o ?g. }
- W4313584518 endingPage "414" @default.
- W4313584518 startingPage "414" @default.
- W4313584518 abstract "We assessed the humanistic and economic burden of chronic red blood cell (RBC) transfusions on patients with β-thalassemia. This cross-sectional, US-based study included adults (≥18 years) who self-reported a β-thalassemia physician diagnosis and had received ≥1 RBC transfusion in the past 6 months. The outcomes included the Functional Assessment of Cancer Therapy-Anemia (FACT-An), Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and ad hoc questions about treatment experience, side effects, direct/indirect costs, and psychological burden. Overall, 100 patients completed the survey, of whom 70% experienced “moderate” to “extremely high” burden due to RBC transfusions, 81% reported iron overload, 42% reported compromised social lives. The mean FACT-An score was 132 (higher score indicates better outcomes; 0–188). Mean scores were 33/52 for fatigue and 20/28 for anemia symptoms in the previous 7 days. Health-related quality of life (HRQoL) temporarily improved after RBC transfusion, although patients continued to experience mild-to-severe depression and anxiety, substantial direct costs, compromised employment, and suboptimal quality of life. Over 6 months, patients dedicated a mean of 173 h to transfusion requirements and incurred out-of-pocket costs of USD 2239 for transfusions and USD 896 for additional care costs. These findings highlight the need for new treatment options to improve patient HRQoL and economic outcomes." @default.
- W4313584518 created "2023-01-06" @default.
- W4313584518 creator A5019179989 @default.
- W4313584518 creator A5022021589 @default.
- W4313584518 creator A5023532992 @default.
- W4313584518 creator A5026698327 @default.
- W4313584518 creator A5028504640 @default.
- W4313584518 creator A5033611579 @default.
- W4313584518 creator A5080670916 @default.
- W4313584518 date "2023-01-04" @default.
- W4313584518 modified "2023-09-25" @default.
- W4313584518 title "Understanding the Association between Red Blood Cell Transfusion Utilization and Humanistic and Economic Burden in Patients with β-Thalassemia from the Patients’ Perspective" @default.
- W4313584518 cites W1986776379 @default.
- W4313584518 cites W1996646363 @default.
- W4313584518 cites W2000445173 @default.
- W4313584518 cites W2021706185 @default.
- W4313584518 cites W2024468305 @default.
- W4313584518 cites W2033316213 @default.
- W4313584518 cites W2043355737 @default.
- W4313584518 cites W2043705607 @default.
- W4313584518 cites W2063931484 @default.
- W4313584518 cites W2086325363 @default.
- W4313584518 cites W2099274262 @default.
- W4313584518 cites W2100714797 @default.
- W4313584518 cites W2120536194 @default.
- W4313584518 cites W2121824589 @default.
- W4313584518 cites W2132322340 @default.
- W4313584518 cites W2162821015 @default.
- W4313584518 cites W2175659752 @default.
- W4313584518 cites W2349732602 @default.
- W4313584518 cites W2520560270 @default.
- W4313584518 cites W2555475623 @default.
- W4313584518 cites W2588717028 @default.
- W4313584518 cites W2885215490 @default.
- W4313584518 cites W2892094305 @default.
- W4313584518 cites W2954515500 @default.
- W4313584518 cites W2963558146 @default.
- W4313584518 cites W2988512326 @default.
- W4313584518 cites W2992010020 @default.
- W4313584518 cites W2998721773 @default.
- W4313584518 cites W3094637556 @default.
- W4313584518 cites W3125016186 @default.
- W4313584518 cites W3187992181 @default.
- W4313584518 doi "https://doi.org/10.3390/jcm12020414" @default.
- W4313584518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36675342" @default.
- W4313584518 hasPublicationYear "2023" @default.
- W4313584518 type Work @default.
- W4313584518 citedByCount "0" @default.
- W4313584518 crossrefType "journal-article" @default.
- W4313584518 hasAuthorship W4313584518A5019179989 @default.
- W4313584518 hasAuthorship W4313584518A5022021589 @default.
- W4313584518 hasAuthorship W4313584518A5023532992 @default.
- W4313584518 hasAuthorship W4313584518A5026698327 @default.
- W4313584518 hasAuthorship W4313584518A5028504640 @default.
- W4313584518 hasAuthorship W4313584518A5033611579 @default.
- W4313584518 hasAuthorship W4313584518A5080670916 @default.
- W4313584518 hasBestOaLocation W43135845181 @default.
- W4313584518 hasConcept C118552586 @default.
- W4313584518 hasConcept C121955636 @default.
- W4313584518 hasConcept C126322002 @default.
- W4313584518 hasConcept C139719470 @default.
- W4313584518 hasConcept C144133560 @default.
- W4313584518 hasConcept C159110408 @default.
- W4313584518 hasConcept C162324750 @default.
- W4313584518 hasConcept C177713679 @default.
- W4313584518 hasConcept C187212893 @default.
- W4313584518 hasConcept C2776867660 @default.
- W4313584518 hasConcept C2777799968 @default.
- W4313584518 hasConcept C2778248108 @default.
- W4313584518 hasConcept C2779951463 @default.
- W4313584518 hasConcept C2780014101 @default.
- W4313584518 hasConcept C558461103 @default.
- W4313584518 hasConcept C6964187 @default.
- W4313584518 hasConcept C71924100 @default.
- W4313584518 hasConceptScore W4313584518C118552586 @default.
- W4313584518 hasConceptScore W4313584518C121955636 @default.
- W4313584518 hasConceptScore W4313584518C126322002 @default.
- W4313584518 hasConceptScore W4313584518C139719470 @default.
- W4313584518 hasConceptScore W4313584518C144133560 @default.
- W4313584518 hasConceptScore W4313584518C159110408 @default.
- W4313584518 hasConceptScore W4313584518C162324750 @default.
- W4313584518 hasConceptScore W4313584518C177713679 @default.
- W4313584518 hasConceptScore W4313584518C187212893 @default.
- W4313584518 hasConceptScore W4313584518C2776867660 @default.
- W4313584518 hasConceptScore W4313584518C2777799968 @default.
- W4313584518 hasConceptScore W4313584518C2778248108 @default.
- W4313584518 hasConceptScore W4313584518C2779951463 @default.
- W4313584518 hasConceptScore W4313584518C2780014101 @default.
- W4313584518 hasConceptScore W4313584518C558461103 @default.
- W4313584518 hasConceptScore W4313584518C6964187 @default.
- W4313584518 hasConceptScore W4313584518C71924100 @default.
- W4313584518 hasIssue "2" @default.
- W4313584518 hasLocation W43135845181 @default.
- W4313584518 hasLocation W43135845182 @default.
- W4313584518 hasLocation W43135845183 @default.
- W4313584518 hasOpenAccess W4313584518 @default.
- W4313584518 hasPrimaryLocation W43135845181 @default.
- W4313584518 hasRelatedWork W1779967659 @default.