Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313587379> ?p ?o ?g. }
- W4313587379 endingPage "137" @default.
- W4313587379 startingPage "137" @default.
- W4313587379 abstract "The growing demand for personalized medicine requires innovation in drug manufacturing to combine versatility with automation. Here, three-dimensional (3D) printing was explored for the production of chitosan (CH)/alginate (ALG)-based hydrogels intended as active dressings for wound healing. ALG hydrogels were loaded with 0.75% w/v silver sulfadiazine (SSD), selected as a drug model commonly used for the therapeutic treatment of infected burn wounds, and four different 3D CH/ALG architectures were designed to modulate the release of this active compound. CH/ALG constructs were characterized by their water content, elasticity and porosity. ALG hydrogels (Young's modulus 0.582 ± 0.019 Mpa) were statistically different in terms of elasticity compared to CH (Young's modulus 0.365 ± 0.015 Mpa) but very similar in terms of swelling properties (water content in ALG: 93.18 ± 0.88% and in CH: 92.76 ± 1.17%). In vitro SSD release tests were performed by using vertical diffusion Franz cells, and statistically significant different behaviors in terms of the amount and kinetics of drugs released were observed as a function of the construct. Moreover, strong antimicrobial potency (100% of growth inhibition) against Staphylococcus aureus and Pseudomonas aeruginosa was demonstrated depending on the type of construct, offering a proof of concept that 3D printing techniques could be efficiently applied to the production of hydrogels for controlled drug delivery." @default.
- W4313587379 created "2023-01-06" @default.
- W4313587379 creator A5015415923 @default.
- W4313587379 creator A5031084525 @default.
- W4313587379 creator A5037764707 @default.
- W4313587379 creator A5049465474 @default.
- W4313587379 creator A5058279020 @default.
- W4313587379 creator A5081904802 @default.
- W4313587379 date "2023-01-04" @default.
- W4313587379 modified "2023-09-30" @default.
- W4313587379 title "3D Printed Chitosan/Alginate Hydrogels for the Controlled Release of Silver Sulfadiazine in Wound Healing Applications: Design, Characterization and Antimicrobial Activity" @default.
- W4313587379 cites W1167059961 @default.
- W4313587379 cites W1199477880 @default.
- W4313587379 cites W1583894294 @default.
- W4313587379 cites W1959582520 @default.
- W4313587379 cites W1969949177 @default.
- W4313587379 cites W1975874954 @default.
- W4313587379 cites W1987190449 @default.
- W4313587379 cites W1988987714 @default.
- W4313587379 cites W2001860507 @default.
- W4313587379 cites W2002760226 @default.
- W4313587379 cites W2024130703 @default.
- W4313587379 cites W2043025035 @default.
- W4313587379 cites W2043628483 @default.
- W4313587379 cites W2047905111 @default.
- W4313587379 cites W2067295285 @default.
- W4313587379 cites W2081456799 @default.
- W4313587379 cites W2084016414 @default.
- W4313587379 cites W2090546103 @default.
- W4313587379 cites W2092967691 @default.
- W4313587379 cites W2104446065 @default.
- W4313587379 cites W2125697213 @default.
- W4313587379 cites W2170578067 @default.
- W4313587379 cites W2298205849 @default.
- W4313587379 cites W2399031825 @default.
- W4313587379 cites W2530382426 @default.
- W4313587379 cites W2558708184 @default.
- W4313587379 cites W2734582351 @default.
- W4313587379 cites W2751240695 @default.
- W4313587379 cites W2753564890 @default.
- W4313587379 cites W2757499578 @default.
- W4313587379 cites W2760581635 @default.
- W4313587379 cites W2784981495 @default.
- W4313587379 cites W2790244053 @default.
- W4313587379 cites W2794869591 @default.
- W4313587379 cites W2804715583 @default.
- W4313587379 cites W2868238225 @default.
- W4313587379 cites W2901600224 @default.
- W4313587379 cites W2914209914 @default.
- W4313587379 cites W2942415783 @default.
- W4313587379 cites W2951432469 @default.
- W4313587379 cites W3023679246 @default.
- W4313587379 cites W3080424507 @default.
- W4313587379 cites W3119130970 @default.
- W4313587379 cites W3188825290 @default.
- W4313587379 cites W4200461750 @default.
- W4313587379 cites W4206357651 @default.
- W4313587379 cites W4213073659 @default.
- W4313587379 cites W4223565839 @default.
- W4313587379 cites W4225135500 @default.
- W4313587379 cites W4243006789 @default.
- W4313587379 cites W4280531690 @default.
- W4313587379 cites W4280545265 @default.
- W4313587379 cites W4283277587 @default.
- W4313587379 cites W4306194487 @default.
- W4313587379 cites W4310590964 @default.
- W4313587379 cites W752653099 @default.
- W4313587379 doi "https://doi.org/10.3390/mi14010137" @default.
- W4313587379 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36677198" @default.
- W4313587379 hasPublicationYear "2023" @default.
- W4313587379 type Work @default.
- W4313587379 citedByCount "7" @default.
- W4313587379 countsByYear W43135873792023 @default.
- W4313587379 crossrefType "journal-article" @default.
- W4313587379 hasAuthorship W4313587379A5015415923 @default.
- W4313587379 hasAuthorship W4313587379A5031084525 @default.
- W4313587379 hasAuthorship W4313587379A5037764707 @default.
- W4313587379 hasAuthorship W4313587379A5049465474 @default.
- W4313587379 hasAuthorship W4313587379A5058279020 @default.
- W4313587379 hasAuthorship W4313587379A5081904802 @default.
- W4313587379 hasBestOaLocation W43135873791 @default.
- W4313587379 hasConcept C108586683 @default.
- W4313587379 hasConcept C127413603 @default.
- W4313587379 hasConcept C136229726 @default.
- W4313587379 hasConcept C141071460 @default.
- W4313587379 hasConcept C159985019 @default.
- W4313587379 hasConcept C171250308 @default.
- W4313587379 hasConcept C178790620 @default.
- W4313587379 hasConcept C185592680 @default.
- W4313587379 hasConcept C188027245 @default.
- W4313587379 hasConcept C192562407 @default.
- W4313587379 hasConcept C2776532303 @default.
- W4313587379 hasConcept C2778269047 @default.
- W4313587379 hasConcept C2778540859 @default.
- W4313587379 hasConcept C2779489039 @default.
- W4313587379 hasConcept C2779732960 @default.
- W4313587379 hasConcept C2779820397 @default.
- W4313587379 hasConcept C2780269544 @default.