Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313588258> ?p ?o ?g. }
- W4313588258 endingPage "318" @default.
- W4313588258 startingPage "318" @default.
- W4313588258 abstract "Cancer-derived exosomes exhibit sophisticated functions, such as proliferation, apoptosis, migration, resistance, and tumor microenvironment changes. Several clinical drugs modulate these exosome functions, but the impacts of natural products are not well understood. Exosome functions are regulated by exosome processing, such as secretion and assembly. The modulation of these exosome-processing genes can exert the anticancer and precancer effects of cancer-derived exosomes. This review focuses on the cancer-derived exosomal miRNAs that regulate exosome processing, acting on the natural-product-modulating cell functions of cancer cells. However, the role of exosomal processing has been overlooked in several studies of exosomal miRNAs and natural products. In this study, utilizing the bioinformatics database (miRDB), the exosome-processing genes of natural-product-modulated exosomal miRNAs were predicted. Consequently, several natural drugs that modulate exosome processing and exosomal miRNAs and regulate cancer cell functions are described here. This review sheds light on and improves our understanding of the modulating effects of exosomal miRNAs and their potential exosomal processing targets on anticancer treatments based on the use of natural products." @default.
- W4313588258 created "2023-01-06" @default.
- W4313588258 creator A5003330387 @default.
- W4313588258 creator A5006129657 @default.
- W4313588258 creator A5021568483 @default.
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- W4313588258 creator A5036682215 @default.
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- W4313588258 creator A5074665298 @default.
- W4313588258 creator A5087294552 @default.
- W4313588258 creator A5089081230 @default.
- W4313588258 date "2023-01-03" @default.
- W4313588258 modified "2023-10-14" @default.
- W4313588258 title "Modulating Effects of Cancer-Derived Exosomal miRNAs and Exosomal Processing by Natural Products" @default.
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