FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313588596> ?p ?o ?g. }

• W4313588596 endingPage "83" @default.
• W4313588596 startingPage "73" @default.
• W4313588596 abstract "Low-density polyethylene microplastics are ingested into the bloodstream and distributed to all the organ tissue, including the hippocampus, causing toxic effects. This research aimed to elucidate the responses of hippocampal neurons to microplastic in the blood based on the expressions of superoxide dismutase (SOD), catalase (CAT) enzymes, malondialdehyde (MDA), 8-oxo-7,8-dihydro-2-deoxyguanosine (8-OHdG) in hippocampal neurons, and blood serum amyloid beta 1-42 (Aβ42) levels using SMART PLS pathway analysis.This was a pure experimental research on Wistar rats with a post-test control group design. Five experimental groups (X1, X2, X3, X4, X5) were given 0.0375 mg, 0.075 mg, 0.15 mg, 0.3 mg, and 0.6 mg of low-density polyethylene microplastics mixed in 2cc distilled water, respectively. Furthermore, except for control (C), the groups received microplastics an oral probe for 90 days.The molecular response of hippocampal neurons of Wistar rats to microplastics in the blood significantly decreased SOD enzyme expression, while CAT enzyme was unaffected. It considerably increased neuronal membrane damage (expression of MDA), increased considerably neuronal deoxyribonucleic acid damage (expression of 8-OHdG), and decreased blood serum Aβ42 levels (pathway analysis, all t-value >1.96).The pathway analysis showed that hippocampal neurons were significantly affected by microplastic particles in the blood." @default.
• W4313588596 created "2023-01-06" @default.
• W4313588596 creator A5010477726 @default.
• W4313588596 creator A5019689426 @default.
• W4313588596 creator A5023516893 @default.
• W4313588596 creator A5026689896 @default.
• W4313588596 creator A5031359825 @default.
• W4313588596 creator A5041728119 @default.
• W4313588596 creator A5043899526 @default.
• W4313588596 creator A5048851079 @default.
• W4313588596 date "2023-01-01" @default.
• W4313588596 modified "2023-10-14" @default.
• W4313588596 title "Wistar Rats Hippocampal Neurons Response to Blood Low-Density Polyethylene Microplastics: A Pathway Analysis of SOD, CAT, MDA, 8-OHdG Expression in Hippocampal Neurons and Blood Serum Aβ42 Levels" @default.
• W4313588596 cites W1563974588 @default.
• W4313588596 cites W2066169076 @default.
• W4313588596 cites W2119479641 @default.
• W4313588596 cites W2167906583 @default.
• W4313588596 cites W2230820137 @default.
• W4313588596 cites W2266454105 @default.
• W4313588596 cites W2329303259 @default.
• W4313588596 cites W2402476636 @default.
• W4313588596 cites W2586603853 @default.
• W4313588596 cites W2608368045 @default.
• W4313588596 cites W2620006951 @default.
• W4313588596 cites W2620099204 @default.
• W4313588596 cites W2737217596 @default.
• W4313588596 cites W2753938917 @default.
• W4313588596 cites W2776544319 @default.
• W4313588596 cites W2790767253 @default.
• W4313588596 cites W2801229377 @default.
• W4313588596 cites W2806355655 @default.
• W4313588596 cites W2895682060 @default.
• W4313588596 cites W2896511627 @default.
• W4313588596 cites W2899465999 @default.
• W4313588596 cites W2903835006 @default.
• W4313588596 cites W2923090208 @default.
• W4313588596 cites W2946017099 @default.
• W4313588596 cites W2948574679 @default.
• W4313588596 cites W2967098215 @default.
• W4313588596 cites W2972186294 @default.
• W4313588596 cites W2973422770 @default.
• W4313588596 cites W2982217662 @default.
• W4313588596 cites W2995724321 @default.
• W4313588596 cites W3006275595 @default.
• W4313588596 cites W3009429909 @default.
• W4313588596 cites W3018919147 @default.
• W4313588596 cites W3025859064 @default.
• W4313588596 cites W3036656245 @default.
• W4313588596 cites W3045251925 @default.
• W4313588596 cites W3047181356 @default.
• W4313588596 cites W3087333805 @default.
• W4313588596 cites W3109968655 @default.
• W4313588596 cites W3153946504 @default.
• W4313588596 cites W3158150483 @default.
• W4313588596 cites W3158183948 @default.
• W4313588596 cites W3199208680 @default.
• W4313588596 cites W4200256361 @default.
• W4313588596 cites W4211139529 @default.
• W4313588596 cites W4220655782 @default.
• W4313588596 cites W4223422453 @default.
• W4313588596 doi "https://doi.org/10.2147/ndt.s396556" @default.
• W4313588596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36636141" @default.
• W4313588596 hasPublicationYear "2023" @default.
• W4313588596 type Work @default.
• W4313588596 citedByCount "2" @default.
• W4313588596 countsByYear W43135885962023 @default.
• W4313588596 crossrefType "journal-article" @default.
• W4313588596 hasAuthorship W4313588596A5010477726 @default.
• W4313588596 hasAuthorship W4313588596A5019689426 @default.
• W4313588596 hasAuthorship W4313588596A5023516893 @default.
• W4313588596 hasAuthorship W4313588596A5026689896 @default.
• W4313588596 hasAuthorship W4313588596A5031359825 @default.
• W4313588596 hasAuthorship W4313588596A5041728119 @default.
• W4313588596 hasAuthorship W4313588596A5043899526 @default.
• W4313588596 hasAuthorship W4313588596A5048851079 @default.
• W4313588596 hasBestOaLocation W43135885961 @default.
• W4313588596 hasConcept C107872376 @default.
• W4313588596 hasConcept C126322002 @default.
• W4313588596 hasConcept C134018914 @default.
• W4313588596 hasConcept C148762608 @default.
• W4313588596 hasConcept C16685009 @default.
• W4313588596 hasConcept C181199279 @default.
• W4313588596 hasConcept C185592680 @default.
• W4313588596 hasConcept C203014093 @default.
• W4313588596 hasConcept C2775838275 @default.
• W4313588596 hasConcept C2776151105 @default.
• W4313588596 hasConcept C2778401633 @default.
• W4313588596 hasConcept C2778979269 @default.
• W4313588596 hasConcept C2780401329 @default.
• W4313588596 hasConcept C2781161787 @default.
• W4313588596 hasConcept C55493867 @default.
• W4313588596 hasConcept C71924100 @default.
• W4313588596 hasConceptScore W4313588596C107872376 @default.
• W4313588596 hasConceptScore W4313588596C126322002 @default.
• W4313588596 hasConceptScore W4313588596C134018914 @default.
• W4313588596 hasConceptScore W4313588596C148762608 @default.
• W4313588596 hasConceptScore W4313588596C16685009 @default.
• W4313588596 hasConceptScore W4313588596C181199279 @default.

• next