Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313593372> ?p ?o ?g. }
- W4313593372 endingPage "104478" @default.
- W4313593372 startingPage "104478" @default.
- W4313593372 abstract "BackgroundDespite the wide range of existing performance measures to evaluate functional status of patients with multiple sclerosis, the heterogeneous nature of the disease hinders clinical characterization and monitoring of disease severity. Speckle tracking ultrasonography is a non-invasive technique to assess isolated muscle function by evaluating the contractile properties of muscle tissue, i.e. muscle strain. The aim of this study was to investigate whether muscle strain measured by speckle tracking ultrasonography could be a useful quantitative measure of muscle function in patients with multiple sclerosis. The criterion validity of muscle strain was compared to that of validated performance measures of upper and lower extremity function.MethodsThis cross-sectional study used baseline data from an explorative observational cohort study (the MUST study). Participants recruited from a hospital outpatient MS clinic underwent speckle tracking ultrasonography of the biceps brachii, supraspinatus, and soleus muscles of the dominant side according to pre-defined submaximal isometric contractions. Participants also completed the Timed 25-Foot Walk Test, the Six Spot Step Test, the 2-minute walking test, the Nine-Hole Peg Test, the 12-item Multiple Sclerosis Walking Scale, and the Oxford Shoulder Score. Gaussian distribution was investigated by visual inspection of normal probability plots and the Shapiro-Wilk test. The Timed 25-Foot Walk Test and Nine-Hole Peg Test were selected as gold standards for function of the lower and upper extremities, respectively. Criterion validity was assessed using Spearman's rank-order correlation coefficient ρ (rho), comparing the muscle strain and performance measures against predefined gold standards. Differences in criterion validity were estimated using squared correlations on the Fischer's Z-scale, with non-parametric bootstrapping to obtain bias-corrected, accelerated bootstrap confidence intervals (95% BCa).ResultsCriterion validity showed good to excellent correlations between the gold standard for lower extremity function and the 2-minute walking test and Six Spot Step Test, and a fair correlation to the 12-item Multiple Sclerosis Walking Scale. No significant correlation was found between the gold standard for upper extremity function and the performance measure. There were no significant correlations between the gold standards and muscle strain.ConclusionThe absence of criterion validity for muscle strain alongside fair to strong criterion validity for the performance measures indicates that speckle tracking ultrasonography assessment of muscle strain is either invalid or evaluates other constructs of multiple sclerosis. Muscle strain assessed by speckle tracking ultrasonography cannot be recommended for the evaluation of treatment effects or disease progression in multiple sclerosis." @default.
- W4313593372 created "2023-01-06" @default.
- W4313593372 creator A5000002028 @default.
- W4313593372 creator A5018056521 @default.
- W4313593372 creator A5031925717 @default.
- W4313593372 creator A5049396220 @default.
- W4313593372 creator A5063309304 @default.
- W4313593372 creator A5078984917 @default.
- W4313593372 creator A5083229086 @default.
- W4313593372 date "2023-02-01" @default.
- W4313593372 modified "2023-10-01" @default.
- W4313593372 title "Criterion validity of muscle strain analyses of skeletal muscle function in patients with multiple sclerosis" @default.
- W4313593372 cites W1696095905 @default.
- W4313593372 cites W1964763334 @default.
- W4313593372 cites W1975030808 @default.
- W4313593372 cites W1975823990 @default.
- W4313593372 cites W2007757525 @default.
- W4313593372 cites W2013639806 @default.
- W4313593372 cites W2030705485 @default.
- W4313593372 cites W2035541251 @default.
- W4313593372 cites W2044019910 @default.
- W4313593372 cites W2047274816 @default.
- W4313593372 cites W2057238715 @default.
- W4313593372 cites W2065565319 @default.
- W4313593372 cites W2071298586 @default.
- W4313593372 cites W2084813602 @default.
- W4313593372 cites W2098291431 @default.
- W4313593372 cites W2104262787 @default.
- W4313593372 cites W2105490558 @default.
- W4313593372 cites W2119752929 @default.
- W4313593372 cites W2124624517 @default.
- W4313593372 cites W2126737632 @default.
- W4313593372 cites W2143567192 @default.
- W4313593372 cites W2145481931 @default.
- W4313593372 cites W2150378783 @default.
- W4313593372 cites W2169119331 @default.
- W4313593372 cites W2521634683 @default.
- W4313593372 cites W2589005373 @default.
- W4313593372 cites W2595558863 @default.
- W4313593372 cites W2755715597 @default.
- W4313593372 cites W2763899537 @default.
- W4313593372 cites W2795753662 @default.
- W4313593372 cites W2811157820 @default.
- W4313593372 cites W2913660499 @default.
- W4313593372 cites W2923854857 @default.
- W4313593372 cites W2947797118 @default.
- W4313593372 cites W3115762049 @default.
- W4313593372 cites W3172843400 @default.
- W4313593372 cites W4200087157 @default.
- W4313593372 cites W4211048507 @default.
- W4313593372 cites W4236463435 @default.
- W4313593372 cites W4283815391 @default.
- W4313593372 cites W4309633143 @default.
- W4313593372 doi "https://doi.org/10.1016/j.msard.2022.104478" @default.
- W4313593372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36603294" @default.
- W4313593372 hasPublicationYear "2023" @default.
- W4313593372 type Work @default.
- W4313593372 citedByCount "0" @default.
- W4313593372 crossrefType "journal-article" @default.
- W4313593372 hasAuthorship W4313593372A5000002028 @default.
- W4313593372 hasAuthorship W4313593372A5018056521 @default.
- W4313593372 hasAuthorship W4313593372A5031925717 @default.
- W4313593372 hasAuthorship W4313593372A5049396220 @default.
- W4313593372 hasAuthorship W4313593372A5063309304 @default.
- W4313593372 hasAuthorship W4313593372A5078984917 @default.
- W4313593372 hasAuthorship W4313593372A5083229086 @default.
- W4313593372 hasBestOaLocation W43135933721 @default.
- W4313593372 hasConcept C101601086 @default.
- W4313593372 hasConcept C103486182 @default.
- W4313593372 hasConcept C118552586 @default.
- W4313593372 hasConcept C119857082 @default.
- W4313593372 hasConcept C126322002 @default.
- W4313593372 hasConcept C141071460 @default.
- W4313593372 hasConcept C182050348 @default.
- W4313593372 hasConcept C1862650 @default.
- W4313593372 hasConcept C2775944032 @default.
- W4313593372 hasConcept C2780640218 @default.
- W4313593372 hasConcept C2780892749 @default.
- W4313593372 hasConcept C2781425419 @default.
- W4313593372 hasConcept C40993552 @default.
- W4313593372 hasConcept C41008148 @default.
- W4313593372 hasConcept C49453240 @default.
- W4313593372 hasConcept C71924100 @default.
- W4313593372 hasConcept C99508421 @default.
- W4313593372 hasConceptScore W4313593372C101601086 @default.
- W4313593372 hasConceptScore W4313593372C103486182 @default.
- W4313593372 hasConceptScore W4313593372C118552586 @default.
- W4313593372 hasConceptScore W4313593372C119857082 @default.
- W4313593372 hasConceptScore W4313593372C126322002 @default.
- W4313593372 hasConceptScore W4313593372C141071460 @default.
- W4313593372 hasConceptScore W4313593372C182050348 @default.
- W4313593372 hasConceptScore W4313593372C1862650 @default.
- W4313593372 hasConceptScore W4313593372C2775944032 @default.
- W4313593372 hasConceptScore W4313593372C2780640218 @default.
- W4313593372 hasConceptScore W4313593372C2780892749 @default.
- W4313593372 hasConceptScore W4313593372C2781425419 @default.
- W4313593372 hasConceptScore W4313593372C40993552 @default.
- W4313593372 hasConceptScore W4313593372C41008148 @default.