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- W4313593974 endingPage "104152" @default.
- W4313593974 startingPage "104152" @default.
- W4313593974 abstract "An increasing number of gene therapy applications necessitate the use of delivery methods that are risk-free, highly effective, highly targeted, and do not cause any threat to the recipient. Due to their modifiable nature with a variety of physicochemical characteristics, nanostructures for nucleic acid (NA) delivery provide an unparalleled possibility to overcome conventional delivery disadvantages. Because nanomaterials are easy to work with, they can be easily designed to interact with any biomolecules or moiety for selective targeting. The expression of DNA and RNA can be altered using NA therapeutic methods like DNA, mRNA, and siRNA, and this area of study has received a significant amount of research attention. Combining gene therapies with nanoscale delivery technologies has greatly increased the number of ways these molecules can be used in medicine and biology, such as for bioanalysis, vaccinations, replacing proteins, and turning genes off. This article provides an overview of NA delivery methods and technologies for molecular diagnostics and treatment for various disorders that urge gene-based therapy. It also describes the design concerns of NA nanodelivery, their amazing attributes, and the significance of these nanomaterials in biological systems and diseased cells and tissues. Further, it explains the limitations that NA nanodelivery poses along with the clinical and technical challenges that it has to overcome to extend this state-of-the-art delivery technology." @default.
- W4313593974 created "2023-01-06" @default.
- W4313593974 creator A5001151856 @default.
- W4313593974 creator A5025519397 @default.
- W4313593974 creator A5048294813 @default.
- W4313593974 creator A5063178344 @default.
- W4313593974 creator A5076606289 @default.
- W4313593974 date "2023-02-01" @default.
- W4313593974 modified "2023-10-16" @default.
- W4313593974 title "Non-viral nucleic acid delivery approach: A boon for state-of-the-art gene delivery" @default.
- W4313593974 cites W1707007402 @default.
- W4313593974 cites W182349513 @default.
- W4313593974 cites W1924252729 @default.
- W4313593974 cites W1945148183 @default.
- W4313593974 cites W1965097716 @default.
- W4313593974 cites W1966962897 @default.
- W4313593974 cites W1968583232 @default.
- W4313593974 cites W1970592466 @default.
- W4313593974 cites W1973579525 @default.
- W4313593974 cites W1978403317 @default.
- W4313593974 cites W1979232921 @default.
- W4313593974 cites W1982953992 @default.
- W4313593974 cites W1988214044 @default.
- W4313593974 cites W1990641613 @default.
- W4313593974 cites W1990796256 @default.
- W4313593974 cites W1991533053 @default.
- W4313593974 cites W1992215904 @default.
- W4313593974 cites W1995770815 @default.
- W4313593974 cites W2000444835 @default.
- W4313593974 cites W2001663214 @default.
- W4313593974 cites W2002151233 @default.
- W4313593974 cites W2008033906 @default.
- W4313593974 cites W2009858479 @default.
- W4313593974 cites W2014495927 @default.
- W4313593974 cites W2015164743 @default.
- W4313593974 cites W2015338160 @default.
- W4313593974 cites W2033999645 @default.
- W4313593974 cites W2039422212 @default.
- W4313593974 cites W2042949277 @default.
- W4313593974 cites W2056611743 @default.
- W4313593974 cites W2073217307 @default.
- W4313593974 cites W2076948580 @default.
- W4313593974 cites W2081644109 @default.
- W4313593974 cites W2082113038 @default.
- W4313593974 cites W2091650131 @default.
- W4313593974 cites W2091651723 @default.
- W4313593974 cites W2096552337 @default.
- W4313593974 cites W2101818306 @default.
- W4313593974 cites W2107638822 @default.
- W4313593974 cites W2108615682 @default.
- W4313593974 cites W2117545092 @default.
- W4313593974 cites W2117954455 @default.
- W4313593974 cites W2118891894 @default.
- W4313593974 cites W2119550206 @default.
- W4313593974 cites W2130166533 @default.
- W4313593974 cites W2133873308 @default.
- W4313593974 cites W2148895371 @default.
- W4313593974 cites W2152429732 @default.
- W4313593974 cites W2159482595 @default.
- W4313593974 cites W2170347395 @default.
- W4313593974 cites W2190204638 @default.
- W4313593974 cites W2197753266 @default.
- W4313593974 cites W2249755146 @default.
- W4313593974 cites W2278748511 @default.
- W4313593974 cites W2297551616 @default.
- W4313593974 cites W2319495483 @default.
- W4313593974 cites W2321877594 @default.
- W4313593974 cites W2331210574 @default.
- W4313593974 cites W2340662778 @default.
- W4313593974 cites W2367863657 @default.
- W4313593974 cites W2407515397 @default.
- W4313593974 cites W2413302280 @default.
- W4313593974 cites W2466566988 @default.
- W4313593974 cites W2469006943 @default.
- W4313593974 cites W2504945737 @default.
- W4313593974 cites W2515127155 @default.
- W4313593974 cites W2522321843 @default.
- W4313593974 cites W2528451823 @default.
- W4313593974 cites W2562957244 @default.
- W4313593974 cites W2564108037 @default.
- W4313593974 cites W2566100154 @default.
- W4313593974 cites W2567116069 @default.
- W4313593974 cites W2568387898 @default.
- W4313593974 cites W2586652387 @default.
- W4313593974 cites W2587871737 @default.
- W4313593974 cites W2591025507 @default.
- W4313593974 cites W2592524531 @default.
- W4313593974 cites W2594133976 @default.
- W4313593974 cites W2605342716 @default.
- W4313593974 cites W2607356458 @default.
- W4313593974 cites W2612785372 @default.
- W4313593974 cites W2615256066 @default.
- W4313593974 cites W2624317658 @default.
- W4313593974 cites W2652705574 @default.
- W4313593974 cites W2749722012 @default.
- W4313593974 cites W2753503561 @default.
- W4313593974 cites W2763272720 @default.
- W4313593974 cites W2769848125 @default.