FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313594987> ?p ?o ?g. }

• W4313594987 endingPage "270" @default.
• W4313594987 startingPage "245" @default.
• W4313594987 abstract "Serine-threonine kinase (STK11), also known as liver kinase B1 (LKB1), is a regulator of cellular homeostasis through regulating the cellular ATP-to-ADP ratio. LKB1 is classified as a tumor suppressor and functions as the key activator of AMP-activated protein kinase (AMPK) and a family of serine-threonine kinases called AMPK-like proteins. These proteins include novel (nua) kinase family 1 (NUAK1 and 2), salt inducible kinase (SIK1), QIK (known as SIK2), QSK (known as SIK3 kinase), and maternal embryonic leuzine zipper kinase (MELK) on tightly controlled and specific residual sites. LKB1 also regulates brain selective kinases 1 and 2 (BRSK1 and 2), additional members of AMPK-like protein family, which functions are probably less studied. AMPK-like proteins play a role in variety of reproductive physiology functions such as follicular maturation, menopause, embryogenesis, oocyte maturation, and preimplantation development. In addition, dysfunctional activity of AMPK-like proteins contributes to apoptosis blockade in cancer cells and induction of the epithelial-mesenchymal transition required for metastasis. Dysregulation of these proteins occurs in ovarian, endometrial, and cervical cancers. AMPK-like proteins are still undergoing further classification and may represent novel targets for targeted gynecologic cancer therapies. In this chapter, we describe the AMPK-like family of proteins and their roles in reproductive physiology and gynecologic cancers." @default.
• W4313594987 created "2023-01-06" @default.
• W4313594987 creator A5041133745 @default.
• W4313594987 creator A5055830989 @default.
• W4313594987 creator A5062386111 @default.
• W4313594987 date "2023-01-01" @default.
• W4313594987 modified "2023-09-27" @default.
• W4313594987 title "AMPK-like proteins and their function in female reproduction and gynecologic cancer" @default.
• W4313594987 cites W1529336528 @default.
• W4313594987 cites W1840986764 @default.
• W4313594987 cites W1886732586 @default.
• W4313594987 cites W1923069688 @default.
• W4313594987 cites W1966910195 @default.
• W4313594987 cites W1968069804 @default.
• W4313594987 cites W1970302470 @default.
• W4313594987 cites W1970707684 @default.
• W4313594987 cites W1974228534 @default.
• W4313594987 cites W1975554671 @default.
• W4313594987 cites W1976492308 @default.
• W4313594987 cites W1976760923 @default.
• W4313594987 cites W1988625266 @default.
• W4313594987 cites W1990278643 @default.
• W4313594987 cites W1999146507 @default.
• W4313594987 cites W2001443225 @default.
• W4313594987 cites W2008757142 @default.
• W4313594987 cites W2010667931 @default.
• W4313594987 cites W2015501861 @default.
• W4313594987 cites W2022982388 @default.
• W4313594987 cites W2025727601 @default.
• W4313594987 cites W2026338211 @default.
• W4313594987 cites W2027450812 @default.
• W4313594987 cites W2031459394 @default.
• W4313594987 cites W2033497590 @default.
• W4313594987 cites W2036196881 @default.
• W4313594987 cites W2040113580 @default.
• W4313594987 cites W2044874695 @default.
• W4313594987 cites W2052498320 @default.
• W4313594987 cites W2054606674 @default.
• W4313594987 cites W2055130200 @default.
• W4313594987 cites W2056452291 @default.
• W4313594987 cites W2063368579 @default.
• W4313594987 cites W2065725084 @default.
• W4313594987 cites W2065876308 @default.
• W4313594987 cites W2067156757 @default.
• W4313594987 cites W2075711878 @default.
• W4313594987 cites W2084583623 @default.
• W4313594987 cites W2096701271 @default.
• W4313594987 cites W2097795389 @default.
• W4313594987 cites W2098698214 @default.
• W4313594987 cites W2100215155 @default.
• W4313594987 cites W2102891343 @default.
• W4313594987 cites W2103386246 @default.
• W4313594987 cites W2111900617 @default.
• W4313594987 cites W2115286566 @default.
• W4313594987 cites W2116651275 @default.
• W4313594987 cites W2120304463 @default.
• W4313594987 cites W2123429601 @default.
• W4313594987 cites W2124498364 @default.
• W4313594987 cites W2131255017 @default.
• W4313594987 cites W2134436869 @default.
• W4313594987 cites W2134964552 @default.
• W4313594987 cites W2137633794 @default.
• W4313594987 cites W2138319716 @default.
• W4313594987 cites W2140880413 @default.
• W4313594987 cites W2148614367 @default.
• W4313594987 cites W2152263980 @default.
• W4313594987 cites W2154589460 @default.
• W4313594987 cites W2155598285 @default.
• W4313594987 cites W2160615487 @default.
• W4313594987 cites W2167215996 @default.
• W4313594987 cites W2170285284 @default.
• W4313594987 cites W2268381213 @default.
• W4313594987 cites W2320228393 @default.
• W4313594987 cites W2320447509 @default.
• W4313594987 cites W2342506335 @default.
• W4313594987 cites W2345163484 @default.
• W4313594987 cites W2359382339 @default.
• W4313594987 cites W2462514513 @default.
• W4313594987 cites W2501351815 @default.
• W4313594987 cites W2527517048 @default.
• W4313594987 cites W2550634277 @default.
• W4313594987 cites W2594404528 @default.
• W4313594987 cites W2763871199 @default.
• W4313594987 cites W2888311246 @default.
• W4313594987 cites W2901482699 @default.
• W4313594987 cites W2966596554 @default.
• W4313594987 cites W2991213577 @default.
• W4313594987 cites W2999623704 @default.
• W4313594987 cites W3025755455 @default.
• W4313594987 cites W3048511516 @default.
• W4313594987 cites W3080651327 @default.
• W4313594987 cites W3101148330 @default.
• W4313594987 cites W3134463479 @default.
• W4313594987 cites W3205023315 @default.
• W4313594987 cites W3207786979 @default.
• W4313594987 cites W4205248685 @default.
• W4313594987 cites W4211047904 @default.
• W4313594987 cites W4241579402 @default.

• next