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• W4313595835 startingPage "1224" @default.
• W4313595835 abstract "Trace staphylococcal enterotoxin C (SEC) in food poses a serious risk to human health, and it is vital to develop a sensitive and accurate approach for SEC monitoring. Herein, a surface-enhanced Raman scattering (SERS) aptasensor was developed for the quantitative detection of SEC. SERS-active gold-silver Janus@gold nanoparticles (Au-Ag Janus@Au NPs) were prepared and showed tunable solid and hollow nanostructures by simply controlling the pH values of the reaction system. Solid Au-Ag Janus@Au NPs exhibited intrinsic and enhanced SERS activity due to the intense plasmonic coupling effect between Au dots and Au-Ag Janus NPs, which was 2.27-fold and 17.46-fold higher than that of Au-Ag Janus NPs and hollow Au-Ag Janus@Au NPs, respectively. The attachment of multiple Au dots also protected Ag islands from oxidization, which increased the stability of Au-Ag Janus@Au NPs. Solid Au-Ag Janus@Au NPs served as a label-free, strong, and stable SERS detection probe and achieved sensitive and reliable detection of SEC. The limit of detection was as low as 0.55 pg/mL. This study will expand the application prospects of label-free SERS detection probes in complex systems for food safety monitoring." @default.
• W4313595835 created "2023-01-06" @default.
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• W4313595835 date "2023-01-06" @default.
• W4313595835 modified "2023-10-01" @default.
• W4313595835 title "Tunable Preparation of SERS-Active Au–Ag Janus@Au NPs for Label-Free <i>Staphylococcal Enterotoxin C</i> Detection" @default.
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• W4313595835 doi "https://doi.org/10.1021/acs.jafc.2c08147" @default.
• W4313595835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36606875" @default.
• W4313595835 hasPublicationYear "2023" @default.
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