Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313597850> ?p ?o ?g. }
- W4313597850 endingPage "100114" @default.
- W4313597850 startingPage "100114" @default.
- W4313597850 abstract "Dysfunctional top-down pain modulation is a hallmark of fibromyalgia (FM) and physical exercise is a cornerstone in FM treatment. The aim of this study was to explore the effects of a 15-week intervention of strengthening exercises, twice per week, supervised by a physiotherapist, on exercise-induced hypoalgesia (EIH) and cerebral pain processing in FM patients and healthy controls (HC). FM patients (n = 59) and HC (n = 39) who completed the exercise intervention as part of a multicenter study were examined at baseline and following the intervention. Following the exercise intervention, FM patients reported a reduction of pain intensity, fibromyalgia severity and depression. Reduced EIH was seen in FM patients compared to HC at baseline and no improvement of EIH was seen following the 15-week resistance exercise intervention in either group. Furthermore, a subsample (Stockholm site: FM n = 18; HC n = 19) was also examined with functional magnetic resonance imaging (fMRI) during subjectively calibrated thumbnail pressure pain stimulations at baseline and following intervention. A significant main effect of exercise (post > pre) was observed both in FM patients and HC, in pain-related brain activation within left dorsolateral prefrontal cortex and caudate, as well as increased functional connectivity between caudate and occipital lobe bordering cerebellum (driven by the FM patients). In conclusion, the results indicate that 15-week resistance exercise affect pain-related processing within the cortico-striatal-occipital networks (involved in motor control and cognition), rather than directly influencing top-down descending pain inhibition. In alignment with this, exercise-induced hypoalgesia remained unaltered." @default.
- W4313597850 created "2023-01-06" @default.
- W4313597850 creator A5009758954 @default.
- W4313597850 creator A5012502944 @default.
- W4313597850 creator A5046225760 @default.
- W4313597850 creator A5048017178 @default.
- W4313597850 creator A5072651880 @default.
- W4313597850 creator A5076537832 @default.
- W4313597850 creator A5087218277 @default.
- W4313597850 creator A5087300063 @default.
- W4313597850 date "2023-01-01" @default.
- W4313597850 modified "2023-10-01" @default.
- W4313597850 title "The effects of a 15-week physical exercise intervention on pain modulation in fibromyalgia: Increased pain-related processing within the cortico-striatal- occipital networks, but no improvement of exercise-induced hypoalgesia" @default.
- W4313597850 cites W1567257801 @default.
- W4313597850 cites W1582349367 @default.
- W4313597850 cites W18427948 @default.
- W4313597850 cites W1895939981 @default.
- W4313597850 cites W190502661 @default.
- W4313597850 cites W1966628524 @default.
- W4313597850 cites W1967791807 @default.
- W4313597850 cites W1968654102 @default.
- W4313597850 cites W1975954553 @default.
- W4313597850 cites W1987138256 @default.
- W4313597850 cites W1992215919 @default.
- W4313597850 cites W1998806270 @default.
- W4313597850 cites W2003386656 @default.
- W4313597850 cites W2010322515 @default.
- W4313597850 cites W2022897802 @default.
- W4313597850 cites W2024176835 @default.
- W4313597850 cites W2046504031 @default.
- W4313597850 cites W2047196117 @default.
- W4313597850 cites W2058077818 @default.
- W4313597850 cites W2059634785 @default.
- W4313597850 cites W2071994929 @default.
- W4313597850 cites W2086551541 @default.
- W4313597850 cites W2088035788 @default.
- W4313597850 cites W2095575861 @default.
- W4313597850 cites W2100083513 @default.
- W4313597850 cites W2104440316 @default.
- W4313597850 cites W2130933293 @default.
- W4313597850 cites W2134807533 @default.
- W4313597850 cites W2135953149 @default.
- W4313597850 cites W2144351977 @default.
- W4313597850 cites W2149421654 @default.
- W4313597850 cites W2150306023 @default.
- W4313597850 cites W2150951635 @default.
- W4313597850 cites W2172080594 @default.
- W4313597850 cites W2253364553 @default.
- W4313597850 cites W2331694814 @default.
- W4313597850 cites W2395888859 @default.
- W4313597850 cites W2410227523 @default.
- W4313597850 cites W2414635989 @default.
- W4313597850 cites W2416671902 @default.
- W4313597850 cites W2473039652 @default.
- W4313597850 cites W2529084878 @default.
- W4313597850 cites W2592360091 @default.
- W4313597850 cites W2592646799 @default.
- W4313597850 cites W2592818396 @default.
- W4313597850 cites W2604834320 @default.
- W4313597850 cites W2626342298 @default.
- W4313597850 cites W2667698269 @default.
- W4313597850 cites W2766857187 @default.
- W4313597850 cites W2790266628 @default.
- W4313597850 cites W2798091161 @default.
- W4313597850 cites W2800104237 @default.
- W4313597850 cites W2801527337 @default.
- W4313597850 cites W2802261936 @default.
- W4313597850 cites W2808152380 @default.
- W4313597850 cites W2886446833 @default.
- W4313597850 cites W2891285073 @default.
- W4313597850 cites W2895807487 @default.
- W4313597850 cites W2902070300 @default.
- W4313597850 cites W2924109670 @default.
- W4313597850 cites W2953101257 @default.
- W4313597850 cites W2986233914 @default.
- W4313597850 cites W3005927757 @default.
- W4313597850 cites W3088466406 @default.
- W4313597850 cites W3134304694 @default.
- W4313597850 cites W3161747450 @default.
- W4313597850 cites W4241221200 @default.
- W4313597850 doi "https://doi.org/10.1016/j.ynpai.2023.100114" @default.
- W4313597850 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36660198" @default.
- W4313597850 hasPublicationYear "2023" @default.
- W4313597850 type Work @default.
- W4313597850 citedByCount "1" @default.
- W4313597850 countsByYear W43135978502023 @default.
- W4313597850 crossrefType "journal-article" @default.
- W4313597850 hasAuthorship W4313597850A5009758954 @default.
- W4313597850 hasAuthorship W4313597850A5012502944 @default.
- W4313597850 hasAuthorship W4313597850A5046225760 @default.
- W4313597850 hasAuthorship W4313597850A5048017178 @default.
- W4313597850 hasAuthorship W4313597850A5072651880 @default.
- W4313597850 hasAuthorship W4313597850A5076537832 @default.
- W4313597850 hasAuthorship W4313597850A5087218277 @default.
- W4313597850 hasAuthorship W4313597850A5087300063 @default.
- W4313597850 hasBestOaLocation W43135978501 @default.
- W4313597850 hasConcept C126322002 @default.
- W4313597850 hasConcept C126838900 @default.