Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313598112> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4313598112 abstract "Despite the recent surge of viral metagenomic studies, recovering complete virus/phage genomes from metagenomic data is still extremely difficult and most viral contigs generated from de novo assembly programs are highly fragmented, posing serious challenges to downstream analysis and inference. In this study, we develop FastViromeExplorer (FVE)-novel, a computational pipeline for reconstructing complete or near-complete viral draft genomes from metagenomic data. The FVE-novel deploys FVE to efficiently map metagenomic reads to viral reference genomes, performs de novo assembly of the mapped reads to generate contigs, and extends the contigs through iterative assembly to produce final viral scaffolds. We applied FVE-novel to an ocean metagenomic sample and obtained 268 viral scaffolds that potentially come from novel viruses. Through manual examination and validation of the 10 longest scaffolds, we successfully recovered 4 complete viral genomes, 2 are novel as they cannot be found in the existing databases and the other 2 are related to known phages. This hybrid reference-based and de novo assembly approach used by FVE-novel represents a powerful new approach for uncovering near-complete viral genomes in metagenomic data." @default.
- W4313598112 created "2023-01-06" @default.
- W4313598112 creator A5015683073 @default.
- W4313598112 creator A5061868278 @default.
- W4313598112 creator A5063912603 @default.
- W4313598112 creator A5064545135 @default.
- W4313598112 date "2023-01-06" @default.
- W4313598112 modified "2023-10-16" @default.
- W4313598112 title "FastViromeExplorer-Novel: Recovering Draft Genomes of Novel Viruses and Phages in Metagenomic Data" @default.
- W4313598112 cites W1552724685 @default.
- W4313598112 cites W1684151570 @default.
- W4313598112 cites W1930975169 @default.
- W4313598112 cites W1996821789 @default.
- W4313598112 cites W2029551594 @default.
- W4313598112 cites W2068687524 @default.
- W4313598112 cites W2084814249 @default.
- W4313598112 cites W2100896078 @default.
- W4313598112 cites W2102619694 @default.
- W4313598112 cites W2107282968 @default.
- W4313598112 cites W2108234281 @default.
- W4313598112 cites W2109848222 @default.
- W4313598112 cites W2118001436 @default.
- W4313598112 cites W2120902911 @default.
- W4313598112 cites W2128880918 @default.
- W4313598112 cites W2143485490 @default.
- W4313598112 cites W2147378425 @default.
- W4313598112 cites W2149981091 @default.
- W4313598112 cites W2150491437 @default.
- W4313598112 cites W2158714788 @default.
- W4313598112 cites W2160174935 @default.
- W4313598112 cites W2168749192 @default.
- W4313598112 cites W2169899471 @default.
- W4313598112 cites W2170551349 @default.
- W4313598112 cites W2170747616 @default.
- W4313598112 cites W2279910557 @default.
- W4313598112 cites W2408892709 @default.
- W4313598112 cites W2470063865 @default.
- W4313598112 cites W2514983714 @default.
- W4313598112 cites W2521169042 @default.
- W4313598112 cites W2592811885 @default.
- W4313598112 cites W2599417231 @default.
- W4313598112 cites W2602855059 @default.
- W4313598112 cites W2763878612 @default.
- W4313598112 cites W2764019192 @default.
- W4313598112 cites W2808035849 @default.
- W4313598112 cites W2892786048 @default.
- W4313598112 cites W2904384071 @default.
- W4313598112 cites W2940459311 @default.
- W4313598112 cites W2949841808 @default.
- W4313598112 cites W3007490551 @default.
- W4313598112 doi "https://doi.org/10.1089/cmb.2022.0397" @default.
- W4313598112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36607772" @default.
- W4313598112 hasPublicationYear "2023" @default.
- W4313598112 type Work @default.
- W4313598112 citedByCount "0" @default.
- W4313598112 crossrefType "journal-article" @default.
- W4313598112 hasAuthorship W4313598112A5015683073 @default.
- W4313598112 hasAuthorship W4313598112A5061868278 @default.
- W4313598112 hasAuthorship W4313598112A5063912603 @default.
- W4313598112 hasAuthorship W4313598112A5064545135 @default.
- W4313598112 hasConcept C104317684 @default.
- W4313598112 hasConcept C141231307 @default.
- W4313598112 hasConcept C150194340 @default.
- W4313598112 hasConcept C15151743 @default.
- W4313598112 hasConcept C162317418 @default.
- W4313598112 hasConcept C18949551 @default.
- W4313598112 hasConcept C54355233 @default.
- W4313598112 hasConcept C59582021 @default.
- W4313598112 hasConcept C70721500 @default.
- W4313598112 hasConcept C86803240 @default.
- W4313598112 hasConceptScore W4313598112C104317684 @default.
- W4313598112 hasConceptScore W4313598112C141231307 @default.
- W4313598112 hasConceptScore W4313598112C150194340 @default.
- W4313598112 hasConceptScore W4313598112C15151743 @default.
- W4313598112 hasConceptScore W4313598112C162317418 @default.
- W4313598112 hasConceptScore W4313598112C18949551 @default.
- W4313598112 hasConceptScore W4313598112C54355233 @default.
- W4313598112 hasConceptScore W4313598112C59582021 @default.
- W4313598112 hasConceptScore W4313598112C70721500 @default.
- W4313598112 hasConceptScore W4313598112C86803240 @default.
- W4313598112 hasLocation W43135981121 @default.
- W4313598112 hasLocation W43135981122 @default.
- W4313598112 hasOpenAccess W4313598112 @default.
- W4313598112 hasPrimaryLocation W43135981121 @default.
- W4313598112 hasRelatedWork W2078447778 @default.
- W4313598112 hasRelatedWork W2097029864 @default.
- W4313598112 hasRelatedWork W2200318732 @default.
- W4313598112 hasRelatedWork W2337508844 @default.
- W4313598112 hasRelatedWork W2794277665 @default.
- W4313598112 hasRelatedWork W2897233545 @default.
- W4313598112 hasRelatedWork W2996384775 @default.
- W4313598112 hasRelatedWork W3005528502 @default.
- W4313598112 hasRelatedWork W3128872455 @default.
- W4313598112 hasRelatedWork W4313598112 @default.
- W4313598112 isParatext "false" @default.
- W4313598112 isRetracted "false" @default.
- W4313598112 workType "article" @default.