Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313638020> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4313638020 endingPage "S259" @default.
- W4313638020 startingPage "S259" @default.
- W4313638020 abstract "Longer breastfeeding duration is associated with lower rates of postpartum depression, but the underlying mechanism is not known. We sought to quantify the association between maternal experience of breastfeeding and HPA axis activity. We analyzed data from the Mood, Mother, and Infant Study. Feeding intention was assessed in the 3rd trimester, and mood symptoms, antidepressant use, and breastfeeding intensity were assessed monthly in the first postpartum year. Breastfeeding experience was assessed using the Maternal Breastfeeding Evaluation Scale (MBSES). Maternal hair was collected at 6 months and analyzed utilizing liquid chromatography-tandem mass spectrometry to assess cortisol and cortisone levels over the prior 3 months. We used T tests, Pearson correlation, and linear regression to quantify associations between hair corticosteroids and antidepressant use, mood symptoms, breastfeeding intensity, and breastfeeding experience. Hair steroid levels were available for 179 participants, among whom 44 were taking antidepressants at 6 months postpartum. Antidepressant use was associated with higher hair cortisone than non-use (mean (se) 8.68 (0.97) vs. 6.36 (0.33), T test p=0.03), but not with cortisol or cortisol-to-cortisone ratio (p >0.05, Table). Hair cortisone was correlated with weight at the 6 month visit, and inversely correlated with breastfeeding intensity and MBSES, but it was not associated with mood symptoms. In multivariable regression models, we found that antidepressant use modified the association between MBSES and hair cortisone (interaction p=0.02, figure). Among women using antidepressants, a more positive experience of breastfeeding was associated with lower hair cortisone, whereas among women not using antidepressants, breastfeeding experience was not related to hair cortisone levels. Among women being treated for depression, we found that maternal experience of breastfeeding was inversely correlated with hair cortisone levels. These data suggest that the affective experience moderates the effect of breastfeeding on maternal physiology.View Large Image Figure ViewerDownload Hi-res image Download (PPT)" @default.
- W4313638020 created "2023-01-07" @default.
- W4313638020 creator A5000446863 @default.
- W4313638020 creator A5000733521 @default.
- W4313638020 creator A5018852614 @default.
- W4313638020 creator A5066576913 @default.
- W4313638020 creator A5080722511 @default.
- W4313638020 date "2023-01-01" @default.
- W4313638020 modified "2023-09-30" @default.
- W4313638020 title "Antidepressant treatment modifies the association between maternal breastfeeding experience and HPA axis activation" @default.
- W4313638020 doi "https://doi.org/10.1016/j.ajog.2022.11.468" @default.
- W4313638020 hasPublicationYear "2023" @default.
- W4313638020 type Work @default.
- W4313638020 citedByCount "0" @default.
- W4313638020 crossrefType "journal-article" @default.
- W4313638020 hasAuthorship W4313638020A5000446863 @default.
- W4313638020 hasAuthorship W4313638020A5000733521 @default.
- W4313638020 hasAuthorship W4313638020A5018852614 @default.
- W4313638020 hasAuthorship W4313638020A5066576913 @default.
- W4313638020 hasAuthorship W4313638020A5080722511 @default.
- W4313638020 hasConcept C118552586 @default.
- W4313638020 hasConcept C126322002 @default.
- W4313638020 hasConcept C131872663 @default.
- W4313638020 hasConcept C134018914 @default.
- W4313638020 hasConcept C139719470 @default.
- W4313638020 hasConcept C162324750 @default.
- W4313638020 hasConcept C187212893 @default.
- W4313638020 hasConcept C2776283161 @default.
- W4313638020 hasConcept C2776867660 @default.
- W4313638020 hasConcept C2779177272 @default.
- W4313638020 hasConcept C2779234561 @default.
- W4313638020 hasConcept C2780262536 @default.
- W4313638020 hasConcept C2780484280 @default.
- W4313638020 hasConcept C2780733359 @default.
- W4313638020 hasConcept C2781161787 @default.
- W4313638020 hasConcept C3020294031 @default.
- W4313638020 hasConcept C42407357 @default.
- W4313638020 hasConcept C54355233 @default.
- W4313638020 hasConcept C71924100 @default.
- W4313638020 hasConcept C86803240 @default.
- W4313638020 hasConceptScore W4313638020C118552586 @default.
- W4313638020 hasConceptScore W4313638020C126322002 @default.
- W4313638020 hasConceptScore W4313638020C131872663 @default.
- W4313638020 hasConceptScore W4313638020C134018914 @default.
- W4313638020 hasConceptScore W4313638020C139719470 @default.
- W4313638020 hasConceptScore W4313638020C162324750 @default.
- W4313638020 hasConceptScore W4313638020C187212893 @default.
- W4313638020 hasConceptScore W4313638020C2776283161 @default.
- W4313638020 hasConceptScore W4313638020C2776867660 @default.
- W4313638020 hasConceptScore W4313638020C2779177272 @default.
- W4313638020 hasConceptScore W4313638020C2779234561 @default.
- W4313638020 hasConceptScore W4313638020C2780262536 @default.
- W4313638020 hasConceptScore W4313638020C2780484280 @default.
- W4313638020 hasConceptScore W4313638020C2780733359 @default.
- W4313638020 hasConceptScore W4313638020C2781161787 @default.
- W4313638020 hasConceptScore W4313638020C3020294031 @default.
- W4313638020 hasConceptScore W4313638020C42407357 @default.
- W4313638020 hasConceptScore W4313638020C54355233 @default.
- W4313638020 hasConceptScore W4313638020C71924100 @default.
- W4313638020 hasConceptScore W4313638020C86803240 @default.
- W4313638020 hasIssue "1" @default.
- W4313638020 hasLocation W43136380201 @default.
- W4313638020 hasOpenAccess W4313638020 @default.
- W4313638020 hasPrimaryLocation W43136380201 @default.
- W4313638020 hasRelatedWork W1981953352 @default.
- W4313638020 hasRelatedWork W1987354827 @default.
- W4313638020 hasRelatedWork W2053073845 @default.
- W4313638020 hasRelatedWork W2062839436 @default.
- W4313638020 hasRelatedWork W2086273974 @default.
- W4313638020 hasRelatedWork W2098898791 @default.
- W4313638020 hasRelatedWork W2111456652 @default.
- W4313638020 hasRelatedWork W2130284710 @default.
- W4313638020 hasRelatedWork W2142387896 @default.
- W4313638020 hasRelatedWork W3110576929 @default.
- W4313638020 hasVolume "228" @default.
- W4313638020 isParatext "false" @default.
- W4313638020 isRetracted "false" @default.
- W4313638020 workType "article" @default.