Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313641708> ?p ?o ?g. }
- W4313641708 endingPage "103486" @default.
- W4313641708 startingPage "103486" @default.
- W4313641708 abstract "Autism spectrum disorder (ASD) is a heterogenous group of neurodevelopmental disorders (NDDs) with a high unmet medical need. Currently, ASD is diagnosed according to behavior-based criteria that overlook clinical and genomic heterogeneity, thus repeatedly resulting in failed clinical trials. Here, we summarize the scientific evidence pointing to the pressing need to create a precision medicine framework for ASD and other NDDs. We discuss the role of omics and systems biology to characterize more homogeneous disease subtypes with different underlying pathophysiological mechanisms and to determine corresponding tailored treatments. Finally, we provide recent initiatives towards tackling the complexity in NDDs for precision medicine and cost-effective drug discovery." @default.
- W4313641708 created "2023-01-07" @default.
- W4313641708 creator A5005406523 @default.
- W4313641708 creator A5014345656 @default.
- W4313641708 creator A5035265069 @default.
- W4313641708 creator A5053192837 @default.
- W4313641708 creator A5061721864 @default.
- W4313641708 creator A5088519804 @default.
- W4313641708 date "2023-03-01" @default.
- W4313641708 modified "2023-10-14" @default.
- W4313641708 title "Translating precision medicine for autism spectrum disorder: A pressing need" @default.
- W4313641708 cites W1964358779 @default.
- W4313641708 cites W1976555450 @default.
- W4313641708 cites W1977044032 @default.
- W4313641708 cites W1988343204 @default.
- W4313641708 cites W2007626633 @default.
- W4313641708 cites W2017790277 @default.
- W4313641708 cites W2025127135 @default.
- W4313641708 cites W2025450822 @default.
- W4313641708 cites W2055019700 @default.
- W4313641708 cites W2058684270 @default.
- W4313641708 cites W2068042549 @default.
- W4313641708 cites W2103185075 @default.
- W4313641708 cites W2108322879 @default.
- W4313641708 cites W2109214922 @default.
- W4313641708 cites W2112163143 @default.
- W4313641708 cites W2125226755 @default.
- W4313641708 cites W2129179498 @default.
- W4313641708 cites W2146738944 @default.
- W4313641708 cites W2149810560 @default.
- W4313641708 cites W2149959145 @default.
- W4313641708 cites W2153773863 @default.
- W4313641708 cites W2155277287 @default.
- W4313641708 cites W2158063953 @default.
- W4313641708 cites W2263739890 @default.
- W4313641708 cites W2301348266 @default.
- W4313641708 cites W2316811866 @default.
- W4313641708 cites W2336203720 @default.
- W4313641708 cites W2337092408 @default.
- W4313641708 cites W2524440579 @default.
- W4313641708 cites W2524626331 @default.
- W4313641708 cites W2536129703 @default.
- W4313641708 cites W2561837554 @default.
- W4313641708 cites W2586074729 @default.
- W4313641708 cites W2588003167 @default.
- W4313641708 cites W2592680049 @default.
- W4313641708 cites W2593686237 @default.
- W4313641708 cites W2606925384 @default.
- W4313641708 cites W2614349964 @default.
- W4313641708 cites W2616744713 @default.
- W4313641708 cites W2623800443 @default.
- W4313641708 cites W2780364439 @default.
- W4313641708 cites W2793975714 @default.
- W4313641708 cites W2801913374 @default.
- W4313641708 cites W2803899179 @default.
- W4313641708 cites W2809645723 @default.
- W4313641708 cites W2891518646 @default.
- W4313641708 cites W2901218091 @default.
- W4313641708 cites W2903850738 @default.
- W4313641708 cites W2911941403 @default.
- W4313641708 cites W2912923207 @default.
- W4313641708 cites W2921141022 @default.
- W4313641708 cites W2936336589 @default.
- W4313641708 cites W2946294290 @default.
- W4313641708 cites W2946400656 @default.
- W4313641708 cites W2947645951 @default.
- W4313641708 cites W2948003108 @default.
- W4313641708 cites W2963209274 @default.
- W4313641708 cites W2964879416 @default.
- W4313641708 cites W2969167159 @default.
- W4313641708 cites W2978181983 @default.
- W4313641708 cites W2989783162 @default.
- W4313641708 cites W2996106255 @default.
- W4313641708 cites W3000799963 @default.
- W4313641708 cites W3018300137 @default.
- W4313641708 cites W3022708094 @default.
- W4313641708 cites W3027179734 @default.
- W4313641708 cites W3036070105 @default.
- W4313641708 cites W3041781301 @default.
- W4313641708 cites W3047785621 @default.
- W4313641708 cites W3049498686 @default.
- W4313641708 cites W3088092592 @default.
- W4313641708 cites W3106417893 @default.
- W4313641708 cites W3109751191 @default.
- W4313641708 cites W3139087651 @default.
- W4313641708 cites W3154250555 @default.
- W4313641708 cites W3154508015 @default.
- W4313641708 cites W3158971645 @default.
- W4313641708 cites W3174261521 @default.
- W4313641708 cites W3205906848 @default.
- W4313641708 cites W4200080541 @default.
- W4313641708 cites W4200177952 @default.
- W4313641708 cites W4210455405 @default.
- W4313641708 cites W4210708461 @default.
- W4313641708 cites W4214877812 @default.
- W4313641708 cites W4238861495 @default.
- W4313641708 doi "https://doi.org/10.1016/j.drudis.2023.103486" @default.
- W4313641708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36623795" @default.