FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313645626> ?p ?o ?g. }

• W4313645626 abstract "Abstract Purpose Enterobacteriaceae producing extended-spectrum beta-lactamase (ESBL) are common pathogens of UTI in children and their prevalence is increasing worldwide. The aim of this study was to determine risk factors for ESBL-positive UTI and susceptibility to antibiotic treatments. Methods A retrospective cohort study conducted at Rambam Health Care Campus, a tertiary hospital in northern Israel. The study included patients younger than < 18 years old and ESBL positive UTI between January 2017 and December 2019. Patient demographics, previous antibiotic treatment, previous UTI episode, genitourinary tract abnormalities, identified organisms in urine cultures, and sensitivity to antibiotics were recorded. Results A total of 570 children who contributed 639 episodes of community-acquired ESBL UTI with 661 Enterobacteriaceae isolates. The median age was 1.3(IQR:0.69–5.9) years. Female comprised 87.9% of the patients. ESBL isolates were identified in 56 (9.8%) patients. Higher rates of resistance to oral antibiotic treatments were found in the ESBL-positive group compared to the ESBL-negative group; amoxicillin-clavulanic acid (65.2% vs 22.7%, p < 0.001, OR = 6.84), trimethoprim-sulfamethoxazole (59.4% vs 17.6%, p < 0.001, OR = 6.84), ciprofloxacin (34.8% vs 4.5%, p < 0.001, OR = 11.43), and to piperacillin-tazobactam (27.5% vs 6.4%, p < 0.001, OR = 5.54). Neither group was resistant to amikacin or carbapenem. Risk factors for ESBL-positive UTI were antibiotic treatment within the last three months (p = 0.002, OR = 3.68, CI:1.63–8.31) and known ESBL carriage (p < 0.001, OR = 13.18, CI:4.25–40.94). Conclusions Known ESBL carriage and recent antibiotic treatment were risk factors for ESBL UTI. High rate of resistance to oral empiric and prophylactic antibiotic treatments was detected. Amikacin as initial treatment in anticipation of culture susceptibility is reasonable." @default.
• W4313645626 created "2023-01-07" @default.
• W4313645626 creator A5016870134 @default.
• W4313645626 creator A5029869033 @default.
• W4313645626 creator A5031387182 @default.
• W4313645626 creator A5039223942 @default.
• W4313645626 date "2023-01-06" @default.
• W4313645626 modified "2023-10-17" @default.
• W4313645626 title "Risk factors for extended-spectrum beta-lactamase-producing Enterobacteriaceae in community-acquired urinary tract infections in children and susceptibility to commonly used antibiotic treatments" @default.
• W4313645626 cites W1585063521 @default.
• W4313645626 cites W1890693950 @default.
• W4313645626 cites W1904177231 @default.
• W4313645626 cites W1971967129 @default.
• W4313645626 cites W1978456052 @default.
• W4313645626 cites W2024345230 @default.
• W4313645626 cites W2053540856 @default.
• W4313645626 cites W2061042718 @default.
• W4313645626 cites W2072249031 @default.
• W4313645626 cites W2087579452 @default.
• W4313645626 cites W2088970739 @default.
• W4313645626 cites W2092279762 @default.
• W4313645626 cites W2095918352 @default.
• W4313645626 cites W2100016253 @default.
• W4313645626 cites W2140357743 @default.
• W4313645626 cites W2168764308 @default.
• W4313645626 cites W2538811441 @default.
• W4313645626 cites W2579229301 @default.
• W4313645626 cites W2757069010 @default.
• W4313645626 cites W2767128908 @default.
• W4313645626 cites W2794335638 @default.
• W4313645626 cites W2902100453 @default.
• W4313645626 cites W2907649570 @default.
• W4313645626 cites W2922458584 @default.
• W4313645626 cites W2949216464 @default.
• W4313645626 cites W3024584520 @default.
• W4313645626 cites W3125631191 @default.
• W4313645626 cites W3199599890 @default.
• W4313645626 cites W840435558 @default.
• W4313645626 doi "https://doi.org/10.21203/rs.3.rs-2422441/v1" @default.
• W4313645626 hasPublicationYear "2023" @default.
• W4313645626 type Work @default.
• W4313645626 citedByCount "0" @default.
• W4313645626 crossrefType "posted-content" @default.
• W4313645626 hasAuthorship W4313645626A5016870134 @default.
• W4313645626 hasAuthorship W4313645626A5029869033 @default.
• W4313645626 hasAuthorship W4313645626A5031387182 @default.
• W4313645626 hasAuthorship W4313645626A5039223942 @default.
• W4313645626 hasBestOaLocation W43136456261 @default.
• W4313645626 hasConcept C126322002 @default.
• W4313645626 hasConcept C167135981 @default.
• W4313645626 hasConcept C2777427914 @default.
• W4313645626 hasConcept C2777629877 @default.
• W4313645626 hasConcept C2777637488 @default.
• W4313645626 hasConcept C2778193466 @default.
• W4313645626 hasConcept C2778266534 @default.
• W4313645626 hasConcept C2778512257 @default.
• W4313645626 hasConcept C2779425571 @default.
• W4313645626 hasConcept C2779454058 @default.
• W4313645626 hasConcept C2779631663 @default.
• W4313645626 hasConcept C2779708577 @default.
• W4313645626 hasConcept C2780728791 @default.
• W4313645626 hasConcept C501593827 @default.
• W4313645626 hasConcept C523546767 @default.
• W4313645626 hasConcept C54355233 @default.
• W4313645626 hasConcept C71924100 @default.
• W4313645626 hasConcept C77411442 @default.
• W4313645626 hasConcept C86803240 @default.
• W4313645626 hasConcept C89423630 @default.
• W4313645626 hasConcept C94665300 @default.
• W4313645626 hasConceptScore W4313645626C126322002 @default.
• W4313645626 hasConceptScore W4313645626C167135981 @default.
• W4313645626 hasConceptScore W4313645626C2777427914 @default.
• W4313645626 hasConceptScore W4313645626C2777629877 @default.
• W4313645626 hasConceptScore W4313645626C2777637488 @default.
• W4313645626 hasConceptScore W4313645626C2778193466 @default.
• W4313645626 hasConceptScore W4313645626C2778266534 @default.
• W4313645626 hasConceptScore W4313645626C2778512257 @default.
• W4313645626 hasConceptScore W4313645626C2779425571 @default.
• W4313645626 hasConceptScore W4313645626C2779454058 @default.
• W4313645626 hasConceptScore W4313645626C2779631663 @default.
• W4313645626 hasConceptScore W4313645626C2779708577 @default.
• W4313645626 hasConceptScore W4313645626C2780728791 @default.
• W4313645626 hasConceptScore W4313645626C501593827 @default.
• W4313645626 hasConceptScore W4313645626C523546767 @default.
• W4313645626 hasConceptScore W4313645626C54355233 @default.
• W4313645626 hasConceptScore W4313645626C71924100 @default.
• W4313645626 hasConceptScore W4313645626C77411442 @default.
• W4313645626 hasConceptScore W4313645626C86803240 @default.
• W4313645626 hasConceptScore W4313645626C89423630 @default.
• W4313645626 hasConceptScore W4313645626C94665300 @default.
• W4313645626 hasLocation W43136456261 @default.
• W4313645626 hasOpenAccess W4313645626 @default.
• W4313645626 hasPrimaryLocation W43136456261 @default.
• W4313645626 hasRelatedWork W1692409328 @default.
• W4313645626 hasRelatedWork W205899089 @default.
• W4313645626 hasRelatedWork W2121766755 @default.
• W4313645626 hasRelatedWork W2124473065 @default.
• W4313645626 hasRelatedWork W2166714797 @default.
• W4313645626 hasRelatedWork W3010380297 @default.
• W4313645626 hasRelatedWork W3111083268 @default.

• next