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- W4313646329 abstract "The fractionated picosecond laser produces microscopic lesions in the epidermis and dermis due to laser-induced optical breakdown (LIOB). There have been multiple histological reports, but the present literature lacks detailed in vivo studies after treatment with high-power laser systems. Our study aimed to characterize the healing patterns of microlesions induced with 150 ps duration 1064 nm MLA-type picosecond laser. The induced picosecond laser-tissue reactions with pulse energy of 50-250 mJ and different treatment modes were observed in in vivo porcine skin model over 10 days after the laser procedure. A macroscopic evaluation was combined with microscopic histological analysis to observe the healing dynamics of laser-induced microlesions. Superficial, intraepidermal cavitation bubbles were induced using microbeam fluence of 4-20 J/cm2 . Skin irritation scores positively correlated with pulse energy and dose. Our findings demonstrate that dose and pulse energy had a direct impact on epidermal thickness and lesions healing dynamics." @default.
- W4313646329 created "2023-01-07" @default.
- W4313646329 creator A5039232593 @default.
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- W4313646329 date "2023-01-13" @default.
- W4313646329 modified "2023-09-26" @default.
- W4313646329 title "Microlesion healing dynamics in in vivo porcine skin after treatment with 1064 nm picosecond‐domain Nd:<scp>YAG</scp> laser" @default.
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- W4313646329 doi "https://doi.org/10.1002/jbio.202200349" @default.
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