FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313647364> ?p ?o ?g. }

• W4313647364 endingPage "167" @default.
• W4313647364 startingPage "167" @default.
• W4313647364 abstract "The COVID-19 pandemic has created significant concern for everyone. Recent data from many worldwide reports suggest that most infections are caused by the Omicron variant and its sub-lineages, dominating all the previously emerged variants. The numerous mutations in Omicron's viral genome and its sub-lineages attribute it a larger amount of viral fitness, owing to the alteration of the transmission and pathophysiology of the virus. With a rapid change to the viral structure, Omicron and its sub-variants, namely BA.1, BA.2, BA.3, BA.4, and BA.5, dominate the community with an ability to escape the neutralization efficiency induced by prior vaccination or infections. Similarly, several recombinant sub-variants of Omicron, namely XBB, XBD, and XBF, etc., have emerged, which a better understanding. This review mainly entails the changes to Omicron and its sub-lineages due to it having a higher number of mutations. The binding affinity, cellular entry, disease severity, infection rates, and most importantly, the immune evading potential of them are discussed in this review. A comparative analysis of the Delta variant and the other dominating variants that evolved before Omicron gives the readers an in-depth understanding of the landscape of Omicron's transmission and infection. Furthermore, this review discusses the range of neutralization abilities possessed by several approved antiviral therapeutic molecules and neutralizing antibodies which are functional against Omicron and its sub-variants. The rapid evolution of the sub-variants is causing infections, but the broader aspect of their transmission and neutralization has not been explored. Thus, the scientific community should adopt an elucidative approach to obtain a clear idea about the recently emerged sub-variants, including the recombinant variants, so that effective neutralization with vaccines and drugs can be achieved. This, in turn, will lead to a drop in the number of cases and, finally, an end to the pandemic." @default.
• W4313647364 created "2023-01-07" @default.
• W4313647364 creator A5001497588 @default.
• W4313647364 creator A5037330858 @default.
• W4313647364 creator A5048647653 @default.
• W4313647364 creator A5056540491 @default.
• W4313647364 creator A5085223848 @default.
• W4313647364 date "2023-01-05" @default.
• W4313647364 modified "2023-10-09" @default.
• W4313647364 title "A Detailed Overview of SARS-CoV-2 Omicron: Its Sub-Variants, Mutations and Pathophysiology, Clinical Characteristics, Immunological Landscape, Immune Escape, and Therapies" @default.
• W4313647364 cites W3001118548 @default.
• W4313647364 cites W3001897055 @default.
• W4313647364 cites W3002108456 @default.
• W4313647364 cites W3007643904 @default.
• W4313647364 cites W3008572743 @default.
• W4313647364 cites W3008827533 @default.
• W4313647364 cites W3015312944 @default.
• W4313647364 cites W3035786310 @default.
• W4313647364 cites W3036792925 @default.
• W4313647364 cites W3043040397 @default.
• W4313647364 cites W3120079728 @default.
• W4313647364 cites W3127954829 @default.
• W4313647364 cites W3129414840 @default.
• W4313647364 cites W3134208712 @default.
• W4313647364 cites W3135171567 @default.
• W4313647364 cites W3136437538 @default.
• W4313647364 cites W3136588845 @default.
• W4313647364 cites W3136616180 @default.
• W4313647364 cites W3139944324 @default.
• W4313647364 cites W3148264526 @default.
• W4313647364 cites W3159140204 @default.
• W4313647364 cites W3175110658 @default.
• W4313647364 cites W3185488876 @default.
• W4313647364 cites W3192680743 @default.
• W4313647364 cites W3197480610 @default.
• W4313647364 cites W3200630396 @default.
• W4313647364 cites W3211430680 @default.
• W4313647364 cites W3215622646 @default.
• W4313647364 cites W3215827060 @default.
• W4313647364 cites W3217543721 @default.
• W4313647364 cites W4200036115 @default.
• W4313647364 cites W4200059599 @default.
• W4313647364 cites W4200066927 @default.
• W4313647364 cites W4200106058 @default.
• W4313647364 cites W4200108701 @default.
• W4313647364 cites W4200122134 @default.
• W4313647364 cites W4200180765 @default.
• W4313647364 cites W4200293390 @default.
• W4313647364 cites W4200317137 @default.
• W4313647364 cites W4200391585 @default.
• W4313647364 cites W4200414711 @default.
• W4313647364 cites W4200535126 @default.
• W4313647364 cites W4200557555 @default.
• W4313647364 cites W4200628088 @default.
• W4313647364 cites W4205170082 @default.
• W4313647364 cites W4205331651 @default.
• W4313647364 cites W4206106358 @default.
• W4313647364 cites W4206135665 @default.
• W4313647364 cites W4206236780 @default.
• W4313647364 cites W4206737621 @default.
• W4313647364 cites W4206898072 @default.
• W4313647364 cites W4206902820 @default.
• W4313647364 cites W4206950334 @default.
• W4313647364 cites W4206997616 @default.
• W4313647364 cites W4207020509 @default.
• W4313647364 cites W4207050895 @default.
• W4313647364 cites W4207077414 @default.
• W4313647364 cites W4210308999 @default.
• W4313647364 cites W4210338331 @default.
• W4313647364 cites W4210545192 @default.
• W4313647364 cites W4210585911 @default.
• W4313647364 cites W4210665241 @default.
• W4313647364 cites W4210683581 @default.
• W4313647364 cites W4210747042 @default.
• W4313647364 cites W4210787373 @default.
• W4313647364 cites W4210791344 @default.
• W4313647364 cites W4210941782 @default.
• W4313647364 cites W4210943449 @default.
• W4313647364 cites W4211065610 @default.
• W4313647364 cites W4211146823 @default.
• W4313647364 cites W4211176076 @default.
• W4313647364 cites W4213002013 @default.
• W4313647364 cites W4214767539 @default.
• W4313647364 cites W4214845310 @default.
• W4313647364 cites W4220699273 @default.
• W4313647364 cites W4220709838 @default.
• W4313647364 cites W4220758482 @default.
• W4313647364 cites W4220807057 @default.
• W4313647364 cites W4220908383 @default.
• W4313647364 cites W4220987557 @default.
• W4313647364 cites W4221007947 @default.
• W4313647364 cites W4221082445 @default.
• W4313647364 cites W4221116249 @default.
• W4313647364 cites W4221127747 @default.
• W4313647364 cites W4223433648 @default.
• W4313647364 cites W4223451959 @default.
• W4313647364 cites W4223544730 @default.
• W4313647364 cites W4223945501 @default.

• next