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• W4313647521 endingPage "103447" @default.
• W4313647521 startingPage "103447" @default.
• W4313647521 abstract "Persons with schizophrenia and related psychotic disorders (PwS) smoke more, and have twice the rate of mortality, with 10–25 years lower life expectancy than the general population. Evidence-based tobacco cessation interventions would help in quitting. To evaluate the effectiveness of a personalized tobacco cessation intervention package for patients attending the outpatient psychiatry department. The study adopted a two-group experimental design in PwS, using a simple randomization method. Eligible participants were randomly allocated to either the intervention group (n = 85) receiving the intervention package or the control group (n = 85) receiving brief advice to stop tobacco. The study outcomes were measured at baseline, 1, 3, and 6 months. SPSS 23 was used for data analysis. Intention-to-treat analysis was used to manage missing data. The p-value of < 0.05 is considered statistically significant. At 6 months, there was a significant difference (p < 0.001) in 7 days point-prevalence abstinence (28 % vs 10.8 %), reduction of tobacco by at least 50 % (62.4 % vs 40.9 %) with an attrition rate of 15.3 % vs 30.5 % in intervention and control group respectively. Reduction in nicotine dependence and tobacco craving, an increase in motivation level, quit attempts and clinical improvement favored the intervention group. 16.5 % of participants expressed interest in pharmacotherapy for tobacco cessation, 3.5 % were referred to a specialized tobacco cessation center, two control group participants were hospitalized for drug default, and withdrawal symptoms reported were mild. Implementing a tobacco cessation intervention based on the stage of motivation aids in abstinence and reduction of tobacco use in PwS." @default.
• W4313647521 created "2023-01-07" @default.
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• W4313647521 date "2023-03-01" @default.
• W4313647521 modified "2023-09-30" @default.
• W4313647521 title "Effectiveness of personalized tobacco cessation intervention package among patients with schizophrenia and related psychotic disorders – A two-group experimental study" @default.
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• W4313647521 doi "https://doi.org/10.1016/j.ajp.2023.103447" @default.
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• W4313647521 hasPublicationYear "2023" @default.
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