Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313647710> ?p ?o ?g. }
- W4313647710 endingPage "663" @default.
- W4313647710 startingPage "663" @default.
- W4313647710 abstract "The importance of three-dimensional (3D) models in pharmacological tests and personalized therapies is significant. These models allow us to gain insight into the cell response during drug absorption, distribution, metabolism, and elimination in an organ-like system and are suitable for toxicological testing. In personalized and regenerative medicine, the precise characterization of artificial tissues or drug metabolism processes is more than crucial to gain the safest and the most effective treatment for the patients. Using these 3D cell cultures derived directly from patient, such as spheroids, organoids, and bioprinted structures, allows for testing drugs before administration to the patient. These methods allow us to select the most appropriate drug for the patient. Moreover, they provide chance for better recovery of patients, since time is not wasted during therapy switching. These models could be used in applied and basic research as well, because their response to treatments is quite similar to that of the native tissue. Furthermore, they may replace animal models in the future because these methods are cheaper and can avoid interspecies differences. This review puts a spotlight on this dynamically evolving area and its application in toxicological testing." @default.
- W4313647710 created "2023-01-07" @default.
- W4313647710 creator A5001861724 @default.
- W4313647710 creator A5013875540 @default.
- W4313647710 creator A5017439592 @default.
- W4313647710 creator A5056243293 @default.
- W4313647710 creator A5064933071 @default.
- W4313647710 creator A5065175792 @default.
- W4313647710 creator A5090377619 @default.
- W4313647710 date "2023-01-06" @default.
- W4313647710 modified "2023-10-12" @default.
- W4313647710 title "Toward better drug development: Three-dimensional bioprinting in toxicological research" @default.
- W4313647710 cites W1549332315 @default.
- W4313647710 cites W1607851403 @default.
- W4313647710 cites W162723742 @default.
- W4313647710 cites W1968007244 @default.
- W4313647710 cites W1970576651 @default.
- W4313647710 cites W1976249916 @default.
- W4313647710 cites W1979204024 @default.
- W4313647710 cites W1992365665 @default.
- W4313647710 cites W2003905639 @default.
- W4313647710 cites W2004405750 @default.
- W4313647710 cites W2030711777 @default.
- W4313647710 cites W2044928246 @default.
- W4313647710 cites W2080500213 @default.
- W4313647710 cites W2111297916 @default.
- W4313647710 cites W2115609745 @default.
- W4313647710 cites W2124507637 @default.
- W4313647710 cites W2137468287 @default.
- W4313647710 cites W2144685682 @default.
- W4313647710 cites W2203385592 @default.
- W4313647710 cites W2221197034 @default.
- W4313647710 cites W2261624835 @default.
- W4313647710 cites W2264718512 @default.
- W4313647710 cites W2279456626 @default.
- W4313647710 cites W2282335838 @default.
- W4313647710 cites W2295182096 @default.
- W4313647710 cites W2323997176 @default.
- W4313647710 cites W2329056909 @default.
- W4313647710 cites W2329709214 @default.
- W4313647710 cites W2342643254 @default.
- W4313647710 cites W2345415005 @default.
- W4313647710 cites W2345714144 @default.
- W4313647710 cites W2394524191 @default.
- W4313647710 cites W2410993674 @default.
- W4313647710 cites W2417310706 @default.
- W4313647710 cites W2461744008 @default.
- W4313647710 cites W2462042948 @default.
- W4313647710 cites W2472013204 @default.
- W4313647710 cites W2530360197 @default.
- W4313647710 cites W2563494429 @default.
- W4313647710 cites W2572700305 @default.
- W4313647710 cites W2587808031 @default.
- W4313647710 cites W2588705450 @default.
- W4313647710 cites W2594061930 @default.
- W4313647710 cites W2601025682 @default.
- W4313647710 cites W2602807759 @default.
- W4313647710 cites W2603949811 @default.
- W4313647710 cites W2605827552 @default.
- W4313647710 cites W2606980922 @default.
- W4313647710 cites W2608847279 @default.
- W4313647710 cites W2612781596 @default.
- W4313647710 cites W2620256602 @default.
- W4313647710 cites W2625311319 @default.
- W4313647710 cites W2737883714 @default.
- W4313647710 cites W2756161349 @default.
- W4313647710 cites W2773200701 @default.
- W4313647710 cites W2776354711 @default.
- W4313647710 cites W2789608504 @default.
- W4313647710 cites W2792122484 @default.
- W4313647710 cites W2792269963 @default.
- W4313647710 cites W2794144380 @default.
- W4313647710 cites W2794458190 @default.
- W4313647710 cites W2804673796 @default.
- W4313647710 cites W2805627081 @default.
- W4313647710 cites W2809205410 @default.
- W4313647710 cites W2809894170 @default.
- W4313647710 cites W2887409499 @default.
- W4313647710 cites W2887966780 @default.
- W4313647710 cites W2895723582 @default.
- W4313647710 cites W2896319381 @default.
- W4313647710 cites W2900445750 @default.
- W4313647710 cites W2901078894 @default.
- W4313647710 cites W2903148550 @default.
- W4313647710 cites W2906637804 @default.
- W4313647710 cites W2919083791 @default.
- W4313647710 cites W2922284572 @default.
- W4313647710 cites W2936294437 @default.
- W4313647710 cites W2953159556 @default.
- W4313647710 cites W2957480110 @default.
- W4313647710 cites W2958872567 @default.
- W4313647710 cites W2959932413 @default.
- W4313647710 cites W2963914173 @default.
- W4313647710 cites W2971231902 @default.
- W4313647710 cites W2979616312 @default.
- W4313647710 cites W2980195275 @default.
- W4313647710 cites W2986622684 @default.
- W4313647710 cites W2989946055 @default.