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- W4313648731 endingPage "169" @default.
- W4313648731 startingPage "169" @default.
- W4313648731 abstract "Mass spectrometry imaging is a sensitive method for detecting molecules in tissues in their native form. Lipids mainly act as energy stores and membrane constituents, but they also play a role in lipid signaling. Previous studies have suggested an important role of lipids in implantation; therefore, our aim was to investigate the lipid changes during this period based on the available literature. The systematic literature search was performed on Ovid MEDLINE, Cochrane Library, Embase, and LILACS. We included studies about lipid changes in the early embryonal stage of healthy mammalian development published as mass spectrometry imaging. The search retrieved 917 articles without duplicates, and five articles were included in the narrative synthesis of the results. Two articles found a different spatial distribution of lipids in the early bovine embryo and receptive uterus. Three articles investigated lipids in mice in the peri-implantation period and found a different spatial distribution of several glycerophospholipids in both embryonic and maternal tissues. Although only five studies from three different research groups were included in this systematic review, it is clear that the spatial distribution of lipids is diverse in different tissues and their distribution varies from day to day. This may be a key factor in successful implantation, but further studies are needed to elucidate the exact mechanism." @default.
- W4313648731 created "2023-01-07" @default.
- W4313648731 creator A5011056762 @default.
- W4313648731 creator A5031115503 @default.
- W4313648731 creator A5079384579 @default.
- W4313648731 creator A5085679307 @default.
- W4313648731 date "2023-01-06" @default.
- W4313648731 modified "2023-10-14" @default.
- W4313648731 title "Lipid Changes in the Peri-Implantation Period with Mass Spectrometry Imaging: A Systematic Review" @default.
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