FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313654890> ?p ?o ?g. }

• W4313654890 endingPage "101709" @default.
• W4313654890 startingPage "101709" @default.
• W4313654890 abstract "Innate lymphoid cells (ILCs) are a group of innate lymphocytes that do not express RAG-dependent rearranged antigen-specific cell surface receptors. ILCs are classified into five groups according to their developmental trajectory and cytokine production profile. They encompass NK cells, which are cytotoxic, helper-like ILCs 1-3, which functionally mirror CD4+ T helper (Th) type 1, Th2 and Th17 cells respectively, and lymphoid tissue inducer (LTi) cells. NK cell development depends on Eomes (eomesodermin), whereas the ILC1 program is regulated principally by the transcription factor T-bet (T-box transcription factor Tbx21), that of ILC2 is regulated by GATA3 (GATA-binding protein 3) and that of ILC3 is regulated by RORγt (RAR-related orphan receptor γ). NK cells were discovered close to fifty years ago, but ILC1s were first described only about fifteen years ago. Within the ILC family, NK and ILC1s share many similarities, as witnessed by their cell surface phenotype which largely overlap. NK cells and ILC1s have been reported to respond to tissue inflammation and intracellular pathogens. Several studies have reported an antitumorigenic role for NK cells in both humans and mice, but data for ILC1s are both scarce and contradictory. In this review, we will first describe the different NK cell and ILC1 subsets, their effector functions and development. We will then discuss their role in cancer and the effects of the tumor microenvironment on their metabolism." @default.
• W4313654890 created "2023-01-07" @default.
• W4313654890 creator A5022401634 @default.
• W4313654890 creator A5039329858 @default.
• W4313654890 creator A5078486100 @default.
• W4313654890 date "2023-03-01" @default.
• W4313654890 modified "2023-10-01" @default.
• W4313654890 title "Natural killer cells and type 1 innate lymphoid cells in cancer" @default.
• W4313654890 cites W1164981660 @default.
• W4313654890 cites W1476467620 @default.
• W4313654890 cites W1488377901 @default.
• W4313654890 cites W1491394604 @default.
• W4313654890 cites W1499740654 @default.
• W4313654890 cites W1527985047 @default.
• W4313654890 cites W1542501019 @default.
• W4313654890 cites W1579469646 @default.
• W4313654890 cites W1594965720 @default.
• W4313654890 cites W1595949461 @default.
• W4313654890 cites W1663833839 @default.
• W4313654890 cites W1741012896 @default.
• W4313654890 cites W1748587426 @default.
• W4313654890 cites W1755638404 @default.
• W4313654890 cites W1760639175 @default.
• W4313654890 cites W1786051985 @default.
• W4313654890 cites W1801065823 @default.
• W4313654890 cites W1910923123 @default.
• W4313654890 cites W1942756352 @default.
• W4313654890 cites W1963939177 @default.
• W4313654890 cites W1964703707 @default.
• W4313654890 cites W1965119596 @default.
• W4313654890 cites W1966930760 @default.
• W4313654890 cites W1969814796 @default.
• W4313654890 cites W1970209679 @default.
• W4313654890 cites W1970428748 @default.
• W4313654890 cites W1972178991 @default.
• W4313654890 cites W1976026025 @default.
• W4313654890 cites W1976772617 @default.
• W4313654890 cites W1977328847 @default.
• W4313654890 cites W1981851073 @default.
• W4313654890 cites W1983207609 @default.
• W4313654890 cites W1992317131 @default.
• W4313654890 cites W1993565885 @default.
• W4313654890 cites W1993712744 @default.
• W4313654890 cites W1994875855 @default.
• W4313654890 cites W1997849135 @default.
• W4313654890 cites W2005202415 @default.
• W4313654890 cites W2006608981 @default.
• W4313654890 cites W2008926589 @default.
• W4313654890 cites W2013224779 @default.
• W4313654890 cites W2016857233 @default.
• W4313654890 cites W2019796011 @default.
• W4313654890 cites W2019932788 @default.
• W4313654890 cites W2023719946 @default.
• W4313654890 cites W2033289727 @default.
• W4313654890 cites W2036192035 @default.
• W4313654890 cites W2039638023 @default.
• W4313654890 cites W2041953257 @default.
• W4313654890 cites W2042113030 @default.
• W4313654890 cites W2046271789 @default.
• W4313654890 cites W2047972729 @default.
• W4313654890 cites W2047976284 @default.
• W4313654890 cites W2050962105 @default.
• W4313654890 cites W2051103323 @default.
• W4313654890 cites W2051465794 @default.
• W4313654890 cites W2051818303 @default.
• W4313654890 cites W2057214194 @default.
• W4313654890 cites W2057686712 @default.
• W4313654890 cites W2062135418 @default.
• W4313654890 cites W2070569674 @default.
• W4313654890 cites W2071153515 @default.
• W4313654890 cites W2076930004 @default.
• W4313654890 cites W2079767351 @default.
• W4313654890 cites W2080177623 @default.
• W4313654890 cites W2081670280 @default.
• W4313654890 cites W2085402245 @default.
• W4313654890 cites W2088619423 @default.
• W4313654890 cites W2088776557 @default.
• W4313654890 cites W2092705670 @default.
• W4313654890 cites W2093020827 @default.
• W4313654890 cites W2096924830 @default.
• W4313654890 cites W2100039832 @default.
• W4313654890 cites W2102776587 @default.
• W4313654890 cites W2104016369 @default.
• W4313654890 cites W2104584195 @default.
• W4313654890 cites W2104825199 @default.
• W4313654890 cites W2108207978 @default.
• W4313654890 cites W2111065592 @default.
• W4313654890 cites W2116376294 @default.
• W4313654890 cites W2120344463 @default.
• W4313654890 cites W2121141922 @default.
• W4313654890 cites W2125334139 @default.
• W4313654890 cites W2127944870 @default.
• W4313654890 cites W2130051277 @default.
• W4313654890 cites W2131771270 @default.
• W4313654890 cites W2133064156 @default.
• W4313654890 cites W2136221987 @default.
• W4313654890 cites W2136908022 @default.
• W4313654890 cites W2137905106 @default.

• next