FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313656391> ?p ?o ?g. }

• W4313656391 abstract "Abstract Objectives To investigate whether intravenous thrombolysis (IVT) with alteplase (a recombinant tissue plasminogen activator, rt-PA) before endovascular treatment (EVT) is beneficial for acute ischemic stroke (AIS) patients in different periods. Methods This study enrolled a total of 140 patients hospitalized between 2019 and 2022 with AIS from large vessel occlusion (LVO) in the anterior circulation. Those patients were divided into the EVT alone group and IVT + EVT group, in which EVT was preceded by intravenous rt-PA. According to the time from onset to femoral artery puncture, the above two groups were divided into the following subgroups: < 4.5 h, between 4.5 and 6 h, between 6 and 8 h, and between 8 and 10 h. There were 78 patients in the EVT alone group and 62 patients in the IVT + EVT group. Results There was no statistically significant difference in functional independence, recanalization rate, favorable outcome rate, or mortality between the EVT and IVT + EVT groups ( P > 0.05). After adjusting for confounding factors, a lower incidence of intracerebral hemorrhage was observed in the EVT group ( P < 0.05). A comparison of time-dependent efficacy between the two groups showed that within 6–8 h, there were statistically significant differences between admission and postoperation in the National Institutes of Health Stroke Scale scores at 24 h ( P = 0.01) or 7 days ( P = 0.02). Conclusions Although there was no difference in clinical efficacy and safety between the abovementioned two groups, treatment with IVT + EVT could increase the risk of bleeding compared to EVT. Moreover, in the 6–8 h subgroup, the efficacy of EVT alone was better than that of IVT + EVT." @default.
• W4313656391 created "2023-01-07" @default.
• W4313656391 creator A5028490219 @default.
• W4313656391 creator A5030338153 @default.
• W4313656391 creator A5034562948 @default.
• W4313656391 creator A5035976373 @default.
• W4313656391 creator A5039074657 @default.
• W4313656391 creator A5040791262 @default.
• W4313656391 creator A5040793026 @default.
• W4313656391 creator A5047320525 @default.
• W4313656391 creator A5049088719 @default.
• W4313656391 creator A5051480539 @default.
• W4313656391 creator A5058305195 @default.
• W4313656391 creator A5058687102 @default.
• W4313656391 creator A5058965019 @default.
• W4313656391 creator A5059376311 @default.
• W4313656391 creator A5065087222 @default.
• W4313656391 date "2023-01-07" @default.
• W4313656391 modified "2023-09-30" @default.
• W4313656391 title "A study on endovascular treatment alone and bridging treatment for acute ischemic stroke" @default.
• W4313656391 cites W2005397737 @default.
• W4313656391 cites W2033048555 @default.
• W4313656391 cites W2098032054 @default.
• W4313656391 cites W2132357532 @default.
• W4313656391 cites W2139621750 @default.
• W4313656391 cites W2171058244 @default.
• W4313656391 cites W2171165037 @default.
• W4313656391 cites W2176358011 @default.
• W4313656391 cites W2178466040 @default.
• W4313656391 cites W2303559484 @default.
• W4313656391 cites W2336643864 @default.
• W4313656391 cites W2511388967 @default.
• W4313656391 cites W2570585857 @default.
• W4313656391 cites W2579583844 @default.
• W4313656391 cites W2592963423 @default.
• W4313656391 cites W2605444235 @default.
• W4313656391 cites W2767621257 @default.
• W4313656391 cites W2899566544 @default.
• W4313656391 cites W2954687906 @default.
• W4313656391 cites W2980095488 @default.
• W4313656391 cites W2982303713 @default.
• W4313656391 cites W3023339300 @default.
• W4313656391 cites W3033068490 @default.
• W4313656391 cites W3041260673 @default.
• W4313656391 cites W3049273666 @default.
• W4313656391 cites W3123951518 @default.
• W4313656391 cites W3132060044 @default.
• W4313656391 cites W4200106790 @default.
• W4313656391 cites W4255683973 @default.
• W4313656391 doi "https://doi.org/10.1186/s40001-022-00966-8" @default.
• W4313656391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36611184" @default.
• W4313656391 hasPublicationYear "2023" @default.
• W4313656391 type Work @default.
• W4313656391 citedByCount "0" @default.
• W4313656391 crossrefType "journal-article" @default.
• W4313656391 hasAuthorship W4313656391A5028490219 @default.
• W4313656391 hasAuthorship W4313656391A5030338153 @default.
• W4313656391 hasAuthorship W4313656391A5034562948 @default.
• W4313656391 hasAuthorship W4313656391A5035976373 @default.
• W4313656391 hasAuthorship W4313656391A5039074657 @default.
• W4313656391 hasAuthorship W4313656391A5040791262 @default.
• W4313656391 hasAuthorship W4313656391A5040793026 @default.
• W4313656391 hasAuthorship W4313656391A5047320525 @default.
• W4313656391 hasAuthorship W4313656391A5049088719 @default.
• W4313656391 hasAuthorship W4313656391A5051480539 @default.
• W4313656391 hasAuthorship W4313656391A5058305195 @default.
• W4313656391 hasAuthorship W4313656391A5058687102 @default.
• W4313656391 hasAuthorship W4313656391A5058965019 @default.
• W4313656391 hasAuthorship W4313656391A5059376311 @default.
• W4313656391 hasAuthorship W4313656391A5065087222 @default.
• W4313656391 hasBestOaLocation W43136563911 @default.
• W4313656391 hasConcept C120665830 @default.
• W4313656391 hasConcept C121332964 @default.
• W4313656391 hasConcept C126322002 @default.
• W4313656391 hasConcept C127413603 @default.
• W4313656391 hasConcept C141071460 @default.
• W4313656391 hasConcept C164705383 @default.
• W4313656391 hasConcept C2776098176 @default.
• W4313656391 hasConcept C2776572282 @default.
• W4313656391 hasConcept C2777094939 @default.
• W4313656391 hasConcept C2777736543 @default.
• W4313656391 hasConcept C2779581417 @default.
• W4313656391 hasConcept C2780645631 @default.
• W4313656391 hasConcept C3018386432 @default.
• W4313656391 hasConcept C3020199598 @default.
• W4313656391 hasConcept C42219234 @default.
• W4313656391 hasConcept C500558357 @default.
• W4313656391 hasConcept C541997718 @default.
• W4313656391 hasConcept C61511704 @default.
• W4313656391 hasConcept C71924100 @default.
• W4313656391 hasConcept C77350462 @default.
• W4313656391 hasConcept C78519656 @default.
• W4313656391 hasConceptScore W4313656391C120665830 @default.
• W4313656391 hasConceptScore W4313656391C121332964 @default.
• W4313656391 hasConceptScore W4313656391C126322002 @default.
• W4313656391 hasConceptScore W4313656391C127413603 @default.
• W4313656391 hasConceptScore W4313656391C141071460 @default.
• W4313656391 hasConceptScore W4313656391C164705383 @default.
• W4313656391 hasConceptScore W4313656391C2776098176 @default.
• W4313656391 hasConceptScore W4313656391C2776572282 @default.

• next