FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313679506> ?p ?o ?g. }

• W4313679506 endingPage "663" @default.
• W4313679506 startingPage "654" @default.
• W4313679506 abstract "Four direct oral anticoagulants (DOACs) are used in Japan (edoxaban, rivaroxaban, apixaban, and dabigatran); however, few studies have examined the long-term treatment persistence of these DOACs. Furthermore, the factors associated with persistence remain unclear. This single-center, retrospective cohort study enrolled participants who were newly prescribed the 4 DOACs between January 1, 2012, and April 30, 2020. We assessed the treatment persistence rate by calculating the cumulative incidence rate of prescription switch or discontinuation for 5 years from the initial prescription. The factors associated with persistence were examined using multivariate analysis. The edoxaban was used as a reference for comparison with the other DOACs. The persistence rate at 5 years was 52.9% for all DOACs, including 67.0%, 51.6%, 50.2%, and 37.0% for edoxaban, rivaroxaban, apixaban, and dabigatran, respectively. Multivariate analysis revealed that age >65 years (hazard ratio [HR], 0.62 [95%CI, 0.41-0.93]), chronic kidney disease (HR, 1.63 [95%CI, 1.11-2.39]), baseline hemoglobin (HR, 0.85 [95%CI, 0.78-0.93]), diabetes mellitus (HR, 0.51 [95%CI, 0.29-0.93]), and type of DOACs (rivaroxaban: HR, 1.81 [95%CI, 1.03-3.18]; apixaban: HR, 2.00 [95%CI, 1.15-3.48]; and dabigatran: HR, 2.84 [95%CI, 1.66-4.86]) were significantly associated with nonpersistence at 1 year. At 5 years, diabetes mellitus (HR, 0.60 [95%CI, 0.37-0.97]) and type of DOAC were significantly associated with nonpersistence (rivaroxaban: HR, 1.79 [95%CI, 1.09-2.94]; apixaban: HR, 2.04 [95%CI, 1.26-3.31]; and dabigatran: HR, 2.76 [1.73-4.42]). Long-term treatment persistence differed according to the type of DOAC, with edoxaban exhibiting the highest level of persistence. The factors associated with persistence may change over the treatment course, but larger studies are required to generalize our findings." @default.
• W4313679506 created "2023-01-08" @default.
• W4313679506 creator A5014135006 @default.
• W4313679506 creator A5016614724 @default.
• W4313679506 creator A5025505563 @default.
• W4313679506 creator A5028604254 @default.
• W4313679506 creator A5034844432 @default.
• W4313679506 creator A5063792358 @default.
• W4313679506 creator A5067304434 @default.
• W4313679506 creator A5086938735 @default.
• W4313679506 date "2023-02-06" @default.
• W4313679506 modified "2023-10-02" @default.
• W4313679506 title "Comparison of the Treatment Persistence Among 4 Direct Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation: A 5‐Year Retrospective Cohort Study" @default.
• W4313679506 cites W2042533101 @default.
• W4313679506 cites W2072179271 @default.
• W4313679506 cites W2096246254 @default.
• W4313679506 cites W2097854437 @default.
• W4313679506 cites W2101621119 @default.
• W4313679506 cites W2113760558 @default.
• W4313679506 cites W2136489990 @default.
• W4313679506 cites W2152623033 @default.
• W4313679506 cites W2162508946 @default.
• W4313679506 cites W2163557421 @default.
• W4313679506 cites W2164643105 @default.
• W4313679506 cites W2218762394 @default.
• W4313679506 cites W2528314378 @default.
• W4313679506 cites W2592462642 @default.
• W4313679506 cites W2858745820 @default.
• W4313679506 cites W2875968260 @default.
• W4313679506 cites W2902234722 @default.
• W4313679506 cites W2941480216 @default.
• W4313679506 cites W2957544571 @default.
• W4313679506 cites W2979575337 @default.
• W4313679506 cites W2980772371 @default.
• W4313679506 cites W2981320481 @default.
• W4313679506 cites W2991651199 @default.
• W4313679506 cites W3012307018 @default.
• W4313679506 cites W3019819364 @default.
• W4313679506 cites W3082188176 @default.
• W4313679506 cites W3135003830 @default.
• W4313679506 cites W3177890207 @default.
• W4313679506 cites W4226367249 @default.
• W4313679506 doi "https://doi.org/10.1002/jcph.2204" @default.
• W4313679506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36609916" @default.
• W4313679506 hasPublicationYear "2023" @default.
• W4313679506 type Work @default.
• W4313679506 citedByCount "0" @default.
• W4313679506 crossrefType "journal-article" @default.
• W4313679506 hasAuthorship W4313679506A5014135006 @default.
• W4313679506 hasAuthorship W4313679506A5016614724 @default.
• W4313679506 hasAuthorship W4313679506A5025505563 @default.
• W4313679506 hasAuthorship W4313679506A5028604254 @default.
• W4313679506 hasAuthorship W4313679506A5034844432 @default.
• W4313679506 hasAuthorship W4313679506A5063792358 @default.
• W4313679506 hasAuthorship W4313679506A5067304434 @default.
• W4313679506 hasAuthorship W4313679506A5086938735 @default.
• W4313679506 hasConcept C126322002 @default.
• W4313679506 hasConcept C159641895 @default.
• W4313679506 hasConcept C167135981 @default.
• W4313679506 hasConcept C207103383 @default.
• W4313679506 hasConcept C2776301958 @default.
• W4313679506 hasConcept C2778661090 @default.
• W4313679506 hasConcept C2778715236 @default.
• W4313679506 hasConcept C2778810321 @default.
• W4313679506 hasConcept C2779161974 @default.
• W4313679506 hasConcept C2780290652 @default.
• W4313679506 hasConcept C2780638905 @default.
• W4313679506 hasConcept C44249647 @default.
• W4313679506 hasConcept C71924100 @default.
• W4313679506 hasConceptScore W4313679506C126322002 @default.
• W4313679506 hasConceptScore W4313679506C159641895 @default.
• W4313679506 hasConceptScore W4313679506C167135981 @default.
• W4313679506 hasConceptScore W4313679506C207103383 @default.
• W4313679506 hasConceptScore W4313679506C2776301958 @default.
• W4313679506 hasConceptScore W4313679506C2778661090 @default.
• W4313679506 hasConceptScore W4313679506C2778715236 @default.
• W4313679506 hasConceptScore W4313679506C2778810321 @default.
• W4313679506 hasConceptScore W4313679506C2779161974 @default.
• W4313679506 hasConceptScore W4313679506C2780290652 @default.
• W4313679506 hasConceptScore W4313679506C2780638905 @default.
• W4313679506 hasConceptScore W4313679506C44249647 @default.
• W4313679506 hasConceptScore W4313679506C71924100 @default.
• W4313679506 hasIssue "6" @default.
• W4313679506 hasLocation W43136795061 @default.
• W4313679506 hasLocation W43136795062 @default.
• W4313679506 hasOpenAccess W4313679506 @default.
• W4313679506 hasPrimaryLocation W43136795061 @default.
• W4313679506 hasRelatedWork W1972269502 @default.
• W4313679506 hasRelatedWork W2037830341 @default.
• W4313679506 hasRelatedWork W2040951791 @default.
• W4313679506 hasRelatedWork W2126328654 @default.
• W4313679506 hasRelatedWork W2167924766 @default.
• W4313679506 hasRelatedWork W2195369357 @default.
• W4313679506 hasRelatedWork W2811048362 @default.
• W4313679506 hasRelatedWork W3173880122 @default.
• W4313679506 hasRelatedWork W4319019627 @default.
• W4313679506 hasRelatedWork W4386209868 @default.
• W4313679506 hasVolume "63" @default.

• next