Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313703087> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4313703087 endingPage "100624" @default.
- W4313703087 startingPage "100624" @default.
- W4313703087 abstract "Strychnos camptoneura is an essential ethnomedicinal plant of Congolese traditional medicine known for its therapeutic ingredients to prevent, mitigate or treat any diseases or conditions related to skin wounds. The aim was to investigate toxicity and wound healing effects of the S. comptoneura seeds ethanolic extract (EE) using the keratinocytes HaCaT line and dermal fibroblast cells. The keratinocytes and fibroblasts cells used in this study were treated with 0.5–500 μg/ml of the plant extract. Cell viability was assessed by MTT colorimetric assay. The wound-healing effects were evaluated using the wound cellular method by scraping in a 2D environment. Low toxicity was observed with the pure extract at a concentration of 1,56 µg/ml. The cell viability was superior at 70%. Regardless of the cell line type used in vitro, the extract exhibited significant wound healing effects shown by the increasing level of growth factors especially in comparison with the non-treated control group. The TGF-β and TGF-α values at 72 h for dermal fibroblast cells were: (TGF-β) EE 985.2 ± 66.4 pg/ml, control 667.1 ± 26.9 pg/ml; (TGF-α) EE 161.3 ± 11.6 pg/ml, control 98.5 ± 7.8 pg/ml. The results demonstrated that the seeds of S. camptoneura ethanolic extract possessed wound healing activity influenced by an up-regulation in growth factors, which could be explained by the presence of flavonoids. These results could constitute a scientific basis for using S. camptoneura in traditional medicine." @default.
- W4313703087 created "2023-01-08" @default.
- W4313703087 creator A5009686335 @default.
- W4313703087 creator A5033292589 @default.
- W4313703087 creator A5087161753 @default.
- W4313703087 creator A5089189976 @default.
- W4313703087 date "2023-02-01" @default.
- W4313703087 modified "2023-09-26" @default.
- W4313703087 title "In vitro assessment of the wound healing activity of the ethanolic extract of Strychnos camptoneura (Loganiaceae) seeds" @default.
- W4313703087 cites W1601840114 @default.
- W4313703087 cites W1917162171 @default.
- W4313703087 cites W1970516412 @default.
- W4313703087 cites W2016135296 @default.
- W4313703087 cites W2028428401 @default.
- W4313703087 cites W2034466002 @default.
- W4313703087 cites W2036934488 @default.
- W4313703087 cites W2040402086 @default.
- W4313703087 cites W2078958131 @default.
- W4313703087 cites W2087305229 @default.
- W4313703087 cites W2100204308 @default.
- W4313703087 cites W2114918609 @default.
- W4313703087 cites W2146134790 @default.
- W4313703087 cites W2790438241 @default.
- W4313703087 cites W2804246981 @default.
- W4313703087 cites W2909939161 @default.
- W4313703087 cites W2935205699 @default.
- W4313703087 cites W3179916707 @default.
- W4313703087 doi "https://doi.org/10.1016/j.hermed.2023.100624" @default.
- W4313703087 hasPublicationYear "2023" @default.
- W4313703087 type Work @default.
- W4313703087 citedByCount "0" @default.
- W4313703087 crossrefType "journal-article" @default.
- W4313703087 hasAuthorship W4313703087A5009686335 @default.
- W4313703087 hasAuthorship W4313703087A5033292589 @default.
- W4313703087 hasAuthorship W4313703087A5087161753 @default.
- W4313703087 hasAuthorship W4313703087A5089189976 @default.
- W4313703087 hasConcept C118995209 @default.
- W4313703087 hasConcept C126322002 @default.
- W4313703087 hasConcept C185592680 @default.
- W4313703087 hasConcept C202751555 @default.
- W4313703087 hasConcept C203014093 @default.
- W4313703087 hasConcept C2778005187 @default.
- W4313703087 hasConcept C2780269544 @default.
- W4313703087 hasConcept C2780381497 @default.
- W4313703087 hasConcept C2780783641 @default.
- W4313703087 hasConcept C29730261 @default.
- W4313703087 hasConcept C53227056 @default.
- W4313703087 hasConcept C54355233 @default.
- W4313703087 hasConcept C55493867 @default.
- W4313703087 hasConcept C556039675 @default.
- W4313703087 hasConcept C71924100 @default.
- W4313703087 hasConcept C81885089 @default.
- W4313703087 hasConcept C86803240 @default.
- W4313703087 hasConcept C98274493 @default.
- W4313703087 hasConceptScore W4313703087C118995209 @default.
- W4313703087 hasConceptScore W4313703087C126322002 @default.
- W4313703087 hasConceptScore W4313703087C185592680 @default.
- W4313703087 hasConceptScore W4313703087C202751555 @default.
- W4313703087 hasConceptScore W4313703087C203014093 @default.
- W4313703087 hasConceptScore W4313703087C2778005187 @default.
- W4313703087 hasConceptScore W4313703087C2780269544 @default.
- W4313703087 hasConceptScore W4313703087C2780381497 @default.
- W4313703087 hasConceptScore W4313703087C2780783641 @default.
- W4313703087 hasConceptScore W4313703087C29730261 @default.
- W4313703087 hasConceptScore W4313703087C53227056 @default.
- W4313703087 hasConceptScore W4313703087C54355233 @default.
- W4313703087 hasConceptScore W4313703087C55493867 @default.
- W4313703087 hasConceptScore W4313703087C556039675 @default.
- W4313703087 hasConceptScore W4313703087C71924100 @default.
- W4313703087 hasConceptScore W4313703087C81885089 @default.
- W4313703087 hasConceptScore W4313703087C86803240 @default.
- W4313703087 hasConceptScore W4313703087C98274493 @default.
- W4313703087 hasLocation W43137030871 @default.
- W4313703087 hasOpenAccess W4313703087 @default.
- W4313703087 hasPrimaryLocation W43137030871 @default.
- W4313703087 hasRelatedWork W1977496195 @default.
- W4313703087 hasRelatedWork W2025200362 @default.
- W4313703087 hasRelatedWork W2592068980 @default.
- W4313703087 hasRelatedWork W2892350107 @default.
- W4313703087 hasRelatedWork W2901118894 @default.
- W4313703087 hasRelatedWork W2981093092 @default.
- W4313703087 hasRelatedWork W2993996508 @default.
- W4313703087 hasRelatedWork W3135362102 @default.
- W4313703087 hasRelatedWork W4313703087 @default.
- W4313703087 hasRelatedWork W4323029873 @default.
- W4313703087 hasVolume "37" @default.
- W4313703087 isParatext "false" @default.
- W4313703087 isRetracted "false" @default.
- W4313703087 workType "article" @default.