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- W4313731489 abstract "This chapter introduces the effects of arabinoxylan rice bran (Biobran) on hepatitis in animals and humans based on evidence-based research papers. The liver plays an important role in a variety of physiological functions. Liver damage can develop with diseases such as hepatitis and nonalcoholic fatty liver disease (NAFLD). Hepatitis induced by D-galactosamine is a well-studied animal research model that is histologically and pathologically similar to the effects of human hepatitis B virus. Supplementation with Biobran suppressed the D-galactosamine-induced hepatitis and IL-18 expression in rats by inhibition of NF-kappaB and JNK/MAPK expression. Moreover, Biobran supplementation (1 g/day, 3 months) showed suppressed viremia levels in patients infected with chronic hepatitis C virus. In patients with NAFLD, Biobran was consumed 1 g/day for 90 days. The level of alkaline phosphatase significantly decreased in the Biobran feeding group compared to placebo (p < 0.05). More clinical and basic research on Biobran is required in the future to clarify its supportive effects and mechanisms of action in hepatitis." @default.
- W4313731489 created "2023-01-08" @default.
- W4313731489 creator A5078577516 @default.
- W4313731489 date "2023-01-01" @default.
- W4313731489 modified "2023-10-16" @default.
- W4313731489 title "Hepatitis" @default.
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- W4313731489 doi "https://doi.org/10.1007/978-981-19-5735-2_11" @default.
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