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- W4313731556 abstract "Major lifestyle-related chronic diseases, including cancer and Alzheimer’s disease, are the consequences of long-term micro-inflammation in any microenvironment in our body with a latency of 10–20 years. Inflammation is an immune response triggered by leucocytes, such as macrophages and neutrophils, producing and spreading reactive oxygen species in response not only to pathogens but also to self-structural substances, even DNA. Such oxidative stress affects host cells, so-called friendly-fire. One of the worthiest preventive strategies for lifestyle-related diseases is suppression or downregulation of friendly-fire attacks not by drugs but by potent food supplements. Research conducted by the lead author has confirmed the partially absorbed Biobran with its derivatives in mouse blood after oral intake. The uptake of Biobran may be through Peyer’s patches in the small intestines. Further experimentation also demonstrated that both oral intake and parenteral administration of Biobran in mice induced comparable protective effects against the adverse effects of anticancer drugs, which are potent oxidants and even carcinogenic. Hence, the antioxidant, immunomodulating, and anti-inflammatory effects of BioBran can attenuate the “friendly-fire” in lifestyle-related chronic diseases in adulthood and aging." @default.
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- W4313731556 date "2023-01-01" @default.
- W4313731556 modified "2023-10-16" @default.
- W4313731556 title "Chronic Microinflammation as “Friendly-Fire” in Aging and Disease" @default.
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- W4313731556 doi "https://doi.org/10.1007/978-981-19-5735-2_9" @default.
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