FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313813091> ?p ?o ?g. }

• W4313813091 abstract "Abstract Iron deficiency (ID) is the most common nutritional disorder worldwide. It is often observed in patients with chronic diseases, such as heart failure (HF), chronic kidney disease (CKD), inflammatory bowel disease (IBD) and cancer. ID is associated with poor clinical outcome, including poor performance, reduced quality of life, as well as increased hospitalization and mortality. The aim of this review is to provide an overview about the role of ID in chronic diseases (HF, CKD, IBD, cancer) regarding their current definitions and clinical relevance; diagnostic accuracy of iron parameters in chronic inflammatory conditions and its potential as prognostic markers. Due to different definitions and guideline recommendations of ID, various laboratory parameters for ID diagnostic exist and there is no general consensus about the definition of ID and its treatment. Still, a general trend can be observed across all investigated indications of this review (HF, CKD, IBD, cancer) that serum ferritin and transferrin saturation (TSAT) are the two parameters mentioned most often and emphasized in all guidelines to define ID and guide treatment. The most commonly used threshold values for the diagnosis of ID are TSAT of < 20% and serum ferritin of < 100–300 µg/L. Noteworthy, both TSAT and particularly ferritin are frequently applied, but both may vary due to inflammatory conditions. Studies showed that TSAT is less affected by inflammatory processes and may therefore be more accurate and reliable than serum ferritin, particularly in conditions with elevated inflammatory state. A low iron status and particularly a low TSAT value was associated with a poor outcome in all investigated indications, with the strongest evidence in HF patients. Routine surveillance of iron status in these groups of patients with chronic conditions is advisable to detect ID early. Depending on the inflammatory state, TSAT < 20% may be the more accurate diagnostic marker of ID than ferritin. Moreover, TSAT may also be the more reliable estimate for the prognosis, particularly in HF." @default.
• W4313813091 created "2023-01-09" @default.
• W4313813091 creator A5018385979 @default.
• W4313813091 creator A5027966081 @default.
• W4313813091 creator A5042061361 @default.
• W4313813091 date "2023-01-09" @default.
• W4313813091 modified "2023-10-02" @default.
• W4313813091 title "How to diagnose iron deficiency in chronic disease: A review of current methods and potential marker for the outcome" @default.
• W4313813091 cites W12814060 @default.
• W4313813091 cites W1585931985 @default.
• W4313813091 cites W1706624733 @default.
• W4313813091 cites W1773154314 @default.
• W4313813091 cites W1901146837 @default.
• W4313813091 cites W1977560088 @default.
• W4313813091 cites W1990528965 @default.
• W4313813091 cites W2017704094 @default.
• W4313813091 cites W2020198029 @default.
• W4313813091 cites W2033803279 @default.
• W4313813091 cites W2035304843 @default.
• W4313813091 cites W2039385278 @default.
• W4313813091 cites W2044896687 @default.
• W4313813091 cites W2045546593 @default.
• W4313813091 cites W2049258517 @default.
• W4313813091 cites W2055607907 @default.
• W4313813091 cites W2056075569 @default.
• W4313813091 cites W2063871115 @default.
• W4313813091 cites W2077022855 @default.
• W4313813091 cites W2080331075 @default.
• W4313813091 cites W2080896913 @default.
• W4313813091 cites W2086545695 @default.
• W4313813091 cites W2104444347 @default.
• W4313813091 cites W2104810766 @default.
• W4313813091 cites W2107704801 @default.
• W4313813091 cites W2111222598 @default.
• W4313813091 cites W2119134838 @default.
• W4313813091 cites W2123275842 @default.
• W4313813091 cites W2124651950 @default.
• W4313813091 cites W2124903183 @default.
• W4313813091 cites W2126266314 @default.
• W4313813091 cites W2128490296 @default.
• W4313813091 cites W2139318112 @default.
• W4313813091 cites W2151925358 @default.
• W4313813091 cites W2153562137 @default.
• W4313813091 cites W2157846058 @default.
• W4313813091 cites W2166218331 @default.
• W4313813091 cites W2167616828 @default.
• W4313813091 cites W2179606064 @default.
• W4313813091 cites W2298635962 @default.
• W4313813091 cites W2307469285 @default.
• W4313813091 cites W2380765288 @default.
• W4313813091 cites W2415064366 @default.
• W4313813091 cites W2427094903 @default.
• W4313813091 cites W2427645657 @default.
• W4313813091 cites W2436170640 @default.
• W4313813091 cites W2526632948 @default.
• W4313813091 cites W2564022168 @default.
• W4313813091 cites W2574286700 @default.
• W4313813091 cites W2595850779 @default.
• W4313813091 cites W2609605008 @default.
• W4313813091 cites W2609879055 @default.
• W4313813091 cites W2610645021 @default.
• W4313813091 cites W2622043747 @default.
• W4313813091 cites W2737624346 @default.
• W4313813091 cites W2739352460 @default.
• W4313813091 cites W2772301185 @default.
• W4313813091 cites W2786908448 @default.
• W4313813091 cites W2790156897 @default.
• W4313813091 cites W2790659043 @default.
• W4313813091 cites W2890093418 @default.
• W4313813091 cites W2894700795 @default.
• W4313813091 cites W2914295905 @default.
• W4313813091 cites W2930198610 @default.
• W4313813091 cites W2936287417 @default.
• W4313813091 cites W2937356078 @default.
• W4313813091 cites W2946654824 @default.
• W4313813091 cites W2952134395 @default.
• W4313813091 cites W2954028767 @default.
• W4313813091 cites W2956653973 @default.
• W4313813091 cites W2972363302 @default.
• W4313813091 cites W2981434432 @default.
• W4313813091 cites W2982441356 @default.
• W4313813091 cites W3010768198 @default.
• W4313813091 cites W3019812724 @default.
• W4313813091 cites W3106240111 @default.
• W4313813091 cites W3130651443 @default.
• W4313813091 cites W3130976265 @default.
• W4313813091 cites W3133568782 @default.
• W4313813091 cites W3164084589 @default.
• W4313813091 cites W3168199625 @default.
• W4313813091 cites W3189127224 @default.
• W4313813091 cites W3193598686 @default.
• W4313813091 cites W3198574699 @default.
• W4313813091 cites W3201985161 @default.
• W4313813091 cites W4200393455 @default.
• W4313813091 cites W4246583796 @default.
• W4313813091 cites W2254406000 @default.
• W4313813091 doi "https://doi.org/10.1186/s40001-022-00922-6" @default.
• W4313813091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36617559" @default.
• W4313813091 hasPublicationYear "2023" @default.
• W4313813091 type Work @default.

• next