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- W4313815511 abstract "The current study evaluates the role of reactive oxygen species (ROS) in bioeffects of magnetite nanoparticles (MNPs), such as bare (Fe3O4), humic acids (Fe3O4-HA), and 3-aminopropyltriethoxysilane (Fe3O4-APTES) modified MNPs. Mössbauer spectroscopy was used to identify the local surrounding for Fe atom/ions and the depth of modification for MNPs. It was found that the Fe3O4-HA MNPs contain the smallest, whereas the Fe3O4-APTES MNPs contain the largest amount of Fe2+ ions. Bioluminescent cellular and enzymatic assays were applied to monitor the toxicity and anti-(pro-)oxidant activity of MNPs. The contents of ROS were determined by a chemiluminescence luminol assay evaluating the correlations with toxicity/anti-(pro-)oxidant coefficients. Toxic effects of modified MNPs were found at higher concentrations (>10−2 g/L); they were related to ROS storage in bacterial suspensions. MNPs stimulated ROS production by the bacteria in a wide concentration range (10−15−1 g/L). Under the conditions of model oxidative stress and higher concentrations of MNPs (>10−4 g/L), the bacterial bioassay revealed prooxidant activity of all three MNP types, with corresponding decay of ROS content. Bioluminescence enzymatic assay did not show any sensitivity to MNPs, with negligible change in ROS content. The results clearly indicate that cell-membrane processes are responsible for the bioeffects and bacterial ROS generation, confirming the ferroptosis phenomenon based on iron-initiated cell-membrane lipid peroxidation." @default.
- W4313815511 created "2023-01-09" @default.
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- W4313815511 date "2023-01-06" @default.
- W4313815511 modified "2023-09-28" @default.
- W4313815511 title "Functionalized Magnetite Nanoparticles: Characterization, Bioeffects, and Role of Reactive Oxygen Species in Unicellular and Enzymatic Systems" @default.
- W4313815511 cites W1567971153 @default.
- W4313815511 cites W1568010334 @default.
- W4313815511 cites W1595136082 @default.
- W4313815511 cites W1608591555 @default.
- W4313815511 cites W1809723326 @default.
- W4313815511 cites W1964713733 @default.
- W4313815511 cites W1969418262 @default.
- W4313815511 cites W1972799207 @default.
- W4313815511 cites W1977880086 @default.
- W4313815511 cites W1978218216 @default.
- W4313815511 cites W1979026240 @default.
- W4313815511 cites W1985866388 @default.
- W4313815511 cites W1988875770 @default.
- W4313815511 cites W1993706573 @default.
- W4313815511 cites W1993738175 @default.
- W4313815511 cites W1997183854 @default.
- W4313815511 cites W1998820187 @default.
- W4313815511 cites W2000923643 @default.
- W4313815511 cites W2002063000 @default.
- W4313815511 cites W2004504322 @default.
- W4313815511 cites W2005855224 @default.
- W4313815511 cites W2006683077 @default.
- W4313815511 cites W2009613713 @default.
- W4313815511 cites W2017068003 @default.
- W4313815511 cites W2021655143 @default.
- W4313815511 cites W2023546091 @default.
- W4313815511 cites W2034667969 @default.
- W4313815511 cites W2035654546 @default.
- W4313815511 cites W2035957302 @default.
- W4313815511 cites W203873156 @default.
- W4313815511 cites W2039828247 @default.
- W4313815511 cites W2048025022 @default.
- W4313815511 cites W2048594976 @default.
- W4313815511 cites W2054600324 @default.
- W4313815511 cites W2059358438 @default.
- W4313815511 cites W2060439166 @default.
- W4313815511 cites W2060944407 @default.
- W4313815511 cites W2061506478 @default.
- W4313815511 cites W2062769875 @default.
- W4313815511 cites W2064508411 @default.
- W4313815511 cites W2066499253 @default.
- W4313815511 cites W2066659514 @default.
- W4313815511 cites W2067311293 @default.
- W4313815511 cites W2073228236 @default.
- W4313815511 cites W2078593792 @default.
- W4313815511 cites W2084299658 @default.
- W4313815511 cites W2089124524 @default.
- W4313815511 cites W2091922477 @default.
- W4313815511 cites W2093094581 @default.
- W4313815511 cites W2098595088 @default.
- W4313815511 cites W2126346850 @default.
- W4313815511 cites W2127824155 @default.
- W4313815511 cites W2131308754 @default.
- W4313815511 cites W2138968683 @default.
- W4313815511 cites W2145470660 @default.
- W4313815511 cites W2156134614 @default.
- W4313815511 cites W2162932596 @default.
- W4313815511 cites W2165548225 @default.
- W4313815511 cites W2165960269 @default.
- W4313815511 cites W2171447196 @default.
- W4313815511 cites W2194704584 @default.
- W4313815511 cites W2223713506 @default.
- W4313815511 cites W2229268188 @default.
- W4313815511 cites W2236437539 @default.
- W4313815511 cites W2318481944 @default.
- W4313815511 cites W2327681500 @default.
- W4313815511 cites W2411414038 @default.
- W4313815511 cites W2418731129 @default.
- W4313815511 cites W2521319496 @default.
- W4313815511 cites W2551982796 @default.
- W4313815511 cites W2553072551 @default.
- W4313815511 cites W2570849890 @default.
- W4313815511 cites W2729811657 @default.
- W4313815511 cites W2747423355 @default.
- W4313815511 cites W2757854632 @default.
- W4313815511 cites W2786943354 @default.
- W4313815511 cites W2793054103 @default.
- W4313815511 cites W2796380187 @default.
- W4313815511 cites W2885697233 @default.
- W4313815511 cites W2892033747 @default.
- W4313815511 cites W2892326747 @default.
- W4313815511 cites W2907509206 @default.
- W4313815511 cites W2936707779 @default.