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- W4313854611 abstract "In this study, we propose a linear time-varying model of the inter-organ regulatory system. It is well-known that the regulation of energy metabolism is highly controlled by complex metabolic pathways coupled among various organs. On the other hand, a malfunction of this regulatory system can induce various pathological conditions related to the metabolic syndrome, implying that homeostasis of energy expenditure in the inter-organ regulatory system can be treated as a control problem, given an appropriate mathematical model. Moderately abstracting the complex mechanisms and maintaining the comprehensiveness of the inter-organ networks, we construct a simple model comprised of 16 states and 31 rate equations. Since our model is described as a linear time-varying system, it is expected that various control theories can be applied for the model-based analysis of the inter-organ regulatory system." @default.
- W4313854611 created "2023-01-10" @default.
- W4313854611 creator A5057325637 @default.
- W4313854611 creator A5057988879 @default.
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- W4313854611 date "2022-11-27" @default.
- W4313854611 modified "2023-10-18" @default.
- W4313854611 title "Linear time-varying modeling of inter-organ regulatory system" @default.
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- W4313854611 doi "https://doi.org/10.23919/iccas55662.2022.10003882" @default.
- W4313854611 hasPublicationYear "2022" @default.
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