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- W4313855930 abstract "The branches of Millettia brandisiana Kurz were investigated for the first time. A new isoflavone named brandisianone H (1) and a new natural product isoflavone (4′-O-methylelongatin, 2) together with thirteen known compounds were obtained. Compounds 3–10 were reported for the first time from this plant. Their chemical structures were established by spectroscopic analysis and comparison with previously published data. Compound 7 showed a stronger activity against a cholangiocarcinoma cell line (KKU-M156) (IC50 = 2.98 ± 1.08 μg/mL), than the control agent cisplatin (IC50 = 4.88 ± 0.75 μg/mL). Moreover, compounds 1– 3, 6, 7, 9 and 12 – 14 were cytotoxic toward the HepG2 and KKU-M156 cell lines, with IC50 values ranging from 4.76 to 29.71 μg/mL." @default.
- W4313855930 created "2023-01-10" @default.
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- W4313855930 date "2023-02-01" @default.
- W4313855930 modified "2023-10-17" @default.
- W4313855930 title "Chemical constituents from the branches of Millettia brandisiana and their biological activities" @default.
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- W4313855930 doi "https://doi.org/10.1016/j.phytol.2022.12.019" @default.
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