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- W4313880063 endingPage "C437" @default.
- W4313880063 startingPage "C428" @default.
- W4313880063 abstract "Activins and inhibins are unique members of the transforming growth factor-β (TGFβ) family of growth factors, with the ability to exert autocrine, endocrine, and paracrine effects in a wide range of complex physiologic and pathologic processes. Although first isolated within the pituitary, emerging evidence suggests broader influence beyond reproductive development and function. Known roles of activin and inhibin in angiogenesis and immunity along with correlations between gene expression and cancer prognosis suggest potential roles in tumorigenesis. Here, we present a review of the current understanding of the biological role of activins and inhibins as it relates to ovarian cancers, summarizing the underlying signaling mechanisms and physiologic influence, followed by detailing their roles in cancer progression, diagnosis, and treatment." @default.
- W4313880063 created "2023-01-10" @default.
- W4313880063 creator A5019928336 @default.
- W4313880063 creator A5032721580 @default.
- W4313880063 creator A5043625183 @default.
- W4313880063 creator A5078684719 @default.
- W4313880063 date "2023-02-01" @default.
- W4313880063 modified "2023-09-26" @default.
- W4313880063 title "Evolving roles of activins and inhibins in ovarian cancer pathophysiology" @default.
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