Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313887704> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W4313887704 abstract "<p>High intensity focused ultrasound (HIFU) is a form of thermal ablation technique, which can treat a variety of medical afflictions. One promising therapeutic use is the permanent destruction of nerves non-invasively in patients with severe spasticity or certain types of pain (e.g., phantom limb pain). To this end, HIFU requires ultrasound guidance, which allows the non-invasive, target-specific deposition of thermal energy to the targeted nerve, thereby blocking axonal conduction. In this paper, a composite system comprising both ultrasound-imaging and HIFU therapy was developed and used to induce localized non-invasive nerve blockage in an in vivo large animal study. Five pigs were used with the femoral nerve as the target. Calibrated needle thermocouples inserted at the target site were employed to monitor the target tissue temperature. The degree of nerve blockage was assessed by measuring compound action potential (CAP) signal with a clinical nerve electrophysiology system before and after HIFU exposures. An average CAP signal amplitude reduction of 49% of baseline with a standard deviation of 9% was observed after 20-30 min post exposure. These results demonstrate the feasibility of the proposed ultrasound-guided HIFU modality as a potential non-invasive nerve ablation method.</p>" @default.
- W4313887704 created "2023-01-10" @default.
- W4313887704 creator A5013479228 @default.
- W4313887704 creator A5042201308 @default.
- W4313887704 creator A5049720760 @default.
- W4313887704 creator A5075746490 @default.
- W4313887704 creator A5082026989 @default.
- W4313887704 date "2023-01-09" @default.
- W4313887704 modified "2023-10-16" @default.
- W4313887704 title "Image-Guided High Intensity Focused Ultrasound System for Large Animal Nerve Ablation Studies" @default.
- W4313887704 doi "https://doi.org/10.32920/21842484" @default.
- W4313887704 hasPublicationYear "2023" @default.
- W4313887704 type Work @default.
- W4313887704 citedByCount "0" @default.
- W4313887704 crossrefType "posted-content" @default.
- W4313887704 hasAuthorship W4313887704A5013479228 @default.
- W4313887704 hasAuthorship W4313887704A5042201308 @default.
- W4313887704 hasAuthorship W4313887704A5049720760 @default.
- W4313887704 hasAuthorship W4313887704A5075746490 @default.
- W4313887704 hasAuthorship W4313887704A5082026989 @default.
- W4313887704 hasBestOaLocation W43138877041 @default.
- W4313887704 hasConcept C104293457 @default.
- W4313887704 hasConcept C126322002 @default.
- W4313887704 hasConcept C126838900 @default.
- W4313887704 hasConcept C136229726 @default.
- W4313887704 hasConcept C143753070 @default.
- W4313887704 hasConcept C2776101711 @default.
- W4313887704 hasConcept C2777365067 @default.
- W4313887704 hasConcept C2777377203 @default.
- W4313887704 hasConcept C2778902805 @default.
- W4313887704 hasConcept C71924100 @default.
- W4313887704 hasConceptScore W4313887704C104293457 @default.
- W4313887704 hasConceptScore W4313887704C126322002 @default.
- W4313887704 hasConceptScore W4313887704C126838900 @default.
- W4313887704 hasConceptScore W4313887704C136229726 @default.
- W4313887704 hasConceptScore W4313887704C143753070 @default.
- W4313887704 hasConceptScore W4313887704C2776101711 @default.
- W4313887704 hasConceptScore W4313887704C2777365067 @default.
- W4313887704 hasConceptScore W4313887704C2777377203 @default.
- W4313887704 hasConceptScore W4313887704C2778902805 @default.
- W4313887704 hasConceptScore W4313887704C71924100 @default.
- W4313887704 hasLocation W43138877041 @default.
- W4313887704 hasLocation W43138877042 @default.
- W4313887704 hasLocation W43138877043 @default.
- W4313887704 hasOpenAccess W4313887704 @default.
- W4313887704 hasPrimaryLocation W43138877041 @default.
- W4313887704 hasRelatedWork W2018189871 @default.
- W4313887704 hasRelatedWork W2050011232 @default.
- W4313887704 hasRelatedWork W2062780601 @default.
- W4313887704 hasRelatedWork W2112771715 @default.
- W4313887704 hasRelatedWork W2135477061 @default.
- W4313887704 hasRelatedWork W2318675008 @default.
- W4313887704 hasRelatedWork W2416276237 @default.
- W4313887704 hasRelatedWork W2618675588 @default.
- W4313887704 hasRelatedWork W3140857315 @default.
- W4313887704 hasRelatedWork W3164202441 @default.
- W4313887704 isParatext "false" @default.
- W4313887704 isRetracted "false" @default.
- W4313887704 workType "article" @default.