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• W4313889545 abstract "Abstract Physcion is an anthraquinone compound observed dominantly in medicinal herbs. This anthraquinone possesses a variety of pharmaceutically important activities and has been developed to be a widely used antifungal biopesticide. Herein, we report on the effective preparation of 3R -torosachrysone ( 4 ), a tetrahydroanthracene precursor of physcion, in Aspergillus oryzae NSAR1 by heterologous expression of related genes mined from the phlegmacins-producing ascomycete Talaromyces sp. F08Z-0631. Conditions for converting 4 into physcion were studied and optimized, leading to the development of a concise approach for extracting high-purity physcion from the alkali-treated fermentation broth of the 4 -producing A. oryzae strain. Graphical Abstract" @default.
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• W4313889545 date "2023-01-09" @default.
• W4313889545 modified "2023-09-24" @default.
• W4313889545 title "Production of the antifungal biopesticide physcion through the combination of microbial fermentation and chemical post-treatment" @default.
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• W4313889545 doi "https://doi.org/10.1186/s40643-023-00625-8" @default.
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