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- W4313890224 abstract "Hybrid compounds of flavones, namely chrysin and kaempferol, and substituted 1,2,3-triazole derivatives, were synthesized by click reaction of the intermediate O-propargyl derivatives. 4-Fluoro- and 4-nitrobenzyl-1,2,3-triazole-containing hybrid molecules were prepared. The mono- and bis-coupled hybrids were investigated on 60 cell lines of 9 common cancer types (NCI60) in vitro as antitumor agents. Some of them proved to have a significant antiproliferative effect." @default.
- W4313890224 created "2023-01-10" @default.
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- W4313890224 date "2023-01-07" @default.
- W4313890224 modified "2023-10-03" @default.
- W4313890224 title "Synthesis and In Vitro Anticancer Evaluation of Flavone—1,2,3-Triazole Hybrids" @default.
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- W4313890224 doi "https://doi.org/10.3390/molecules28020626" @default.
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