Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313897124> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W4313897124 endingPage "50" @default.
- W4313897124 startingPage "42" @default.
- W4313897124 abstract "Ultra-High Performance Liquid Chromatography (UHPLC) has become the modern standard HPLC platform in recent years. UHPLC as an ideal separation tool for the analysis of complex mixtures with a shorter analysis time is very suitable to be used as a fast and precise method. This study aims to determine the quantitative determination of gabapentin in the form of intermediate products, namely granules and finished products, namely capsules from 1 production batch using the UHPLC method. The results of the quantitative examination of the average content (% recovery) of gabapentin in granule and capsule samples quantified by the UHPLC method met the compendial requirements and internal specifications compared to the standard gabapentin recovery values. The % recovery obtained is 98.254% for gabapentin granules and 97.784% for gabapentin capsules, which means it is still in the 95%-105% range. While the %RSD value is 0.735 for granules and 0.839 for capsules, which means it has an RSD value of <2%. % precision of gabapentin granules was 99.558% with %RSD 0.407, and % intermediate precision gabapentin capsules was obtained 98.845% with %RSD 0.678. In conclusion, based on the quantitative results obtained meet the expected specifications, so it can be considered for use for routine analysis and quality control of medicinal ingredients, in the inspection of intermediate products and other finished drug products in the pharmaceutical industry quickly and accurately." @default.
- W4313897124 created "2023-01-10" @default.
- W4313897124 creator A5004264906 @default.
- W4313897124 date "2022-12-30" @default.
- W4313897124 modified "2023-10-01" @default.
- W4313897124 title "Ultra-High Performance Liquid Chromatography (UHPLC) for Quantification of Gabapentin in Granules and Capsules" @default.
- W4313897124 doi "https://doi.org/10.36341/jops.v6i1.3013" @default.
- W4313897124 hasPublicationYear "2022" @default.
- W4313897124 type Work @default.
- W4313897124 citedByCount "0" @default.
- W4313897124 crossrefType "journal-article" @default.
- W4313897124 hasAuthorship W4313897124A5004264906 @default.
- W4313897124 hasBestOaLocation W43138971241 @default.
- W4313897124 hasConcept C142724271 @default.
- W4313897124 hasConcept C159985019 @default.
- W4313897124 hasConcept C179998833 @default.
- W4313897124 hasConcept C185592680 @default.
- W4313897124 hasConcept C192562407 @default.
- W4313897124 hasConcept C204787440 @default.
- W4313897124 hasConcept C2776608144 @default.
- W4313897124 hasConcept C43617362 @default.
- W4313897124 hasConcept C49760210 @default.
- W4313897124 hasConcept C71924100 @default.
- W4313897124 hasConceptScore W4313897124C142724271 @default.
- W4313897124 hasConceptScore W4313897124C159985019 @default.
- W4313897124 hasConceptScore W4313897124C179998833 @default.
- W4313897124 hasConceptScore W4313897124C185592680 @default.
- W4313897124 hasConceptScore W4313897124C192562407 @default.
- W4313897124 hasConceptScore W4313897124C204787440 @default.
- W4313897124 hasConceptScore W4313897124C2776608144 @default.
- W4313897124 hasConceptScore W4313897124C43617362 @default.
- W4313897124 hasConceptScore W4313897124C49760210 @default.
- W4313897124 hasConceptScore W4313897124C71924100 @default.
- W4313897124 hasIssue "1" @default.
- W4313897124 hasLocation W43138971241 @default.
- W4313897124 hasOpenAccess W4313897124 @default.
- W4313897124 hasPrimaryLocation W43138971241 @default.
- W4313897124 hasRelatedWork W2046024352 @default.
- W4313897124 hasRelatedWork W2055781229 @default.
- W4313897124 hasRelatedWork W2095306786 @default.
- W4313897124 hasRelatedWork W2114353500 @default.
- W4313897124 hasRelatedWork W2145213465 @default.
- W4313897124 hasRelatedWork W2189200885 @default.
- W4313897124 hasRelatedWork W2313641457 @default.
- W4313897124 hasRelatedWork W2352674505 @default.
- W4313897124 hasRelatedWork W2405302437 @default.
- W4313897124 hasRelatedWork W2417209194 @default.
- W4313897124 hasVolume "6" @default.
- W4313897124 isParatext "false" @default.
- W4313897124 isRetracted "false" @default.
- W4313897124 workType "article" @default.