Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315434041> ?p ?o ?g. }
- W4315434041 abstract "Endocrine tumors derive from endocrine cells with high heterogeneity in function, structure and embryology, and are characteristic of a marked diversity and tissue heterogeneity. There are still challenges in analyzing the molecular alternations within the heterogeneous microenvironment for endocrine tumors. Recently, several proteomic, lipidomic and metabolomic platforms have been applied to the analysis of endocrine tumors to explore the cellular and molecular mechanisms of tumor genesis, progression and metastasis. In this review, we provide a comprehensive overview of spatially resolved proteomics, lipidomics and metabolomics guided by mass spectrometry imaging and spatially resolved microproteomics directed by microextraction and tandem mass spectrometry. In this regard, we will discuss different mass spectrometry imaging techniques, including secondary ion mass spectrometry, matrix-assisted laser desorption/ionization and desorption electrospray ionization. Additionally, we will highlight microextraction approaches such as laser capture microdissection and liquid microjunction extraction. With these methods, proteins can be extracted precisely from specific regions of the endocrine tumor. Finally, we compare applications of proteomic, lipidomic and metabolomic platforms in the field of endocrine tumors and outline their potentials in elucidating cellular and molecular processes involved in endocrine tumors." @default.
- W4315434041 created "2023-01-11" @default.
- W4315434041 creator A5001561268 @default.
- W4315434041 creator A5017773158 @default.
- W4315434041 creator A5027932256 @default.
- W4315434041 creator A5032499056 @default.
- W4315434041 creator A5036586131 @default.
- W4315434041 creator A5051571241 @default.
- W4315434041 date "2023-01-10" @default.
- W4315434041 modified "2023-09-28" @default.
- W4315434041 title "Applications of spatially resolved omics in the field of endocrine tumors" @default.
- W4315434041 cites W102743748 @default.
- W4315434041 cites W1511840405 @default.
- W4315434041 cites W1561757844 @default.
- W4315434041 cites W1857656557 @default.
- W4315434041 cites W1902004844 @default.
- W4315434041 cites W1907427644 @default.
- W4315434041 cites W1916568768 @default.
- W4315434041 cites W1936066510 @default.
- W4315434041 cites W1945493283 @default.
- W4315434041 cites W1949466944 @default.
- W4315434041 cites W1967348133 @default.
- W4315434041 cites W1970349598 @default.
- W4315434041 cites W1976208171 @default.
- W4315434041 cites W1980673947 @default.
- W4315434041 cites W1981276008 @default.
- W4315434041 cites W1982241358 @default.
- W4315434041 cites W1982349431 @default.
- W4315434041 cites W1982753051 @default.
- W4315434041 cites W1984603194 @default.
- W4315434041 cites W1992311095 @default.
- W4315434041 cites W1994837336 @default.
- W4315434041 cites W1995755619 @default.
- W4315434041 cites W1996156727 @default.
- W4315434041 cites W1997435180 @default.
- W4315434041 cites W2007607168 @default.
- W4315434041 cites W2009964209 @default.
- W4315434041 cites W2010844713 @default.
- W4315434041 cites W2012216316 @default.
- W4315434041 cites W2014020640 @default.
- W4315434041 cites W2018927663 @default.
- W4315434041 cites W2026103657 @default.
- W4315434041 cites W2029549744 @default.
- W4315434041 cites W2031669752 @default.
- W4315434041 cites W2033278243 @default.
- W4315434041 cites W2036086159 @default.
- W4315434041 cites W2039946906 @default.
- W4315434041 cites W2040862166 @default.
- W4315434041 cites W2041738960 @default.
- W4315434041 cites W2043304722 @default.
- W4315434041 cites W2049583023 @default.
- W4315434041 cites W2052592104 @default.
- W4315434041 cites W2052613838 @default.
- W4315434041 cites W2056211751 @default.
- W4315434041 cites W2057325316 @default.
- W4315434041 cites W2057399242 @default.
- W4315434041 cites W2057734866 @default.
- W4315434041 cites W2064775962 @default.
- W4315434041 cites W2069399470 @default.
- W4315434041 cites W2069792474 @default.
- W4315434041 cites W2076481451 @default.
- W4315434041 cites W2082706499 @default.
- W4315434041 cites W2083486056 @default.
- W4315434041 cites W2084120704 @default.
- W4315434041 cites W2085824809 @default.
- W4315434041 cites W2086306647 @default.
- W4315434041 cites W2089706020 @default.
- W4315434041 cites W2091640905 @default.
- W4315434041 cites W2093010205 @default.
- W4315434041 cites W2094513319 @default.
- W4315434041 cites W2097463865 @default.
- W4315434041 cites W2101936201 @default.
- W4315434041 cites W2106855677 @default.
- W4315434041 cites W2108595785 @default.
- W4315434041 cites W2108741491 @default.
- W4315434041 cites W2116687544 @default.
- W4315434041 cites W2121150388 @default.
- W4315434041 cites W2130796484 @default.
- W4315434041 cites W2134163152 @default.
- W4315434041 cites W2135621660 @default.
- W4315434041 cites W2143277264 @default.
- W4315434041 cites W2143615665 @default.
- W4315434041 cites W2153894482 @default.
- W4315434041 cites W2160621358 @default.
- W4315434041 cites W2191751786 @default.
- W4315434041 cites W2213013819 @default.
- W4315434041 cites W2234115940 @default.
- W4315434041 cites W2273895520 @default.
- W4315434041 cites W2290247287 @default.
- W4315434041 cites W2300944657 @default.
- W4315434041 cites W2302629258 @default.
- W4315434041 cites W2320572375 @default.
- W4315434041 cites W2321577685 @default.
- W4315434041 cites W2332334410 @default.
- W4315434041 cites W2334083046 @default.
- W4315434041 cites W2334176447 @default.
- W4315434041 cites W2341133616 @default.
- W4315434041 cites W2342537821 @default.
- W4315434041 cites W2346267653 @default.
- W4315434041 cites W2400488839 @default.