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- W4315436224 abstract "Neurons cluster into sub-millimeter spatial structures and neural activity occurs at millisecond resolutions; hence, ultimately, high spatial and high temporal resolutions are required for functional MRI. In this work, we implemented a spin-echo line-scanning (SELINE) sequence to use in high spatial and temporal resolution fMRI.A line is formed by simply rotating the spin-echo refocusing gradient to a plane perpendicular to the excited slice and by removing the phase-encoding gradient. This technique promises a combination of high spatial and temporal resolution (250 μm, 500 ms) and microvascular specificity of functional responses. We compared SELINE data to a corresponding gradient-echo version (GELINE).We demonstrate that SELINE showed much-improved line selection (i.e. a sharper line profile) compared to GELINE, albeit at the cost of a significant drop in functional sensitivity.This low functional sensitivity needs to be addressed before SELINE can be applied for neuroscientific purposes." @default.
- W4315436224 created "2023-01-11" @default.
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- W4315436224 date "2023-01-10" @default.
- W4315436224 modified "2023-10-14" @default.
- W4315436224 title "Towards functional spin-echo BOLD line-scanning in humans at 7T" @default.
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- W4315436224 doi "https://doi.org/10.1007/s10334-022-01059-7" @default.
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