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• W4315436680 abstract "The emergence of carbapenem-resistant Enterobacterales (CRE) that coexpress serine- and metallo-carbapenemases is a severe threat to the efficacy of ceftazidime-avibactam (CZA), which has been proven to be extremely effective against KPC-producing Enterobacterales strains. Our study described the cooccurrence of KPC-2, a serine β-lactamase, and IMP-4, a metallo-β-lactamase (MBL), on a conjugative hybrid plasmid from a clinical carbapenem-resistant K. quasipneumoniae strain, and it revealed an alternative route for IncHI5 plasmid to evolve by recombining with other plasmids to form a hybrid plasmid." @default.
• W4315436680 created "2023-01-11" @default.
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• W4315436680 date "2023-02-14" @default.
• W4315436680 modified "2023-10-18" @default.
• W4315436680 title "Characterization of a Conjugative Hybrid Plasmid Coharboring <i>bla</i> _KPC-2 and <i>bla</i> _IMP-4 in a Klebsiella quasipneumoniae Clinical Isolate" @default.
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• W4315436680 doi "https://doi.org/10.1128/spectrum.02616-22" @default.
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