FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315607762> ?p ?o ?g. }

• W4315607762 endingPage "106715" @default.
• W4315607762 startingPage "106715" @default.
• W4315607762 abstract "Miltefosine, an alkylphosphocholine, has been approved recently for the treatment of visceral leishmaniasis. Miltefosine has shown promise as a treatment for paracoccidioidomycosis, and has mixed activity against other fungi and yeast. There are limited data on the in-vitro activity of miltefosine against azole-resistant and -susceptible Aspergillus spp. As such, the aim of this study was to determine the in-vitro activity of miltefosine against Aspergillus strains. Miltefosine was tested against 108 azole-susceptible and -resistant Aspergillus strains isolated from Iran and other countries using the broth microdilution method. Miltefosine was found to be effective against azole-resistant Aspergillus isolates, with minimum inhibitory concentrations (MICs) ranging from 1.562 to 6.25 µg/mL. MIC50 and MIC90 were 1.562 and 3.125 µg/mL, respectively. Miltefosine had a higher geometric mean MIC (2.459 µg/mL) for wild-type Aspergillus isolates than itraconazole (0.220 µg/mL) and voriconazole (0.298 µg/mL). No significant difference was found between miltefosine MICs for azole-resistant Aspergillus isolates and azole-susceptible Aspergillus isolates (P>0.05). Miltefosine appears to have good in-vitro activity against azole-resistant Aspergillus strains, according to these findings. Furthermore, the findings suggest that miltefosine could be used to treat infections caused by azole-resistant Aspergillus spp." @default.
• W4315607762 created "2023-01-12" @default.
• W4315607762 creator A5005968264 @default.
• W4315607762 creator A5006178415 @default.
• W4315607762 creator A5007337085 @default.
• W4315607762 creator A5008253667 @default.
• W4315607762 creator A5011980545 @default.
• W4315607762 creator A5015029026 @default.
• W4315607762 creator A5026585783 @default.
• W4315607762 creator A5028189683 @default.
• W4315607762 creator A5038030716 @default.
• W4315607762 creator A5045526607 @default.
• W4315607762 creator A5055502490 @default.
• W4315607762 creator A5058785356 @default.
• W4315607762 creator A5077775066 @default.
• W4315607762 creator A5084005100 @default.
• W4315607762 creator A5091307770 @default.
• W4315607762 date "2023-03-01" @default.
• W4315607762 modified "2023-10-17" @default.
• W4315607762 title "Antifungal activity of miltefosine against both azole-susceptible and -resistant Aspergillus strains" @default.
• W4315607762 cites W2014668109 @default.
• W4315607762 cites W2016610177 @default.
• W4315607762 cites W2050197274 @default.
• W4315607762 cites W2085846741 @default.
• W4315607762 cites W2096439392 @default.
• W4315607762 cites W2104743902 @default.
• W4315607762 cites W2110507266 @default.
• W4315607762 cites W2125149809 @default.
• W4315607762 cites W2159246552 @default.
• W4315607762 cites W2305251607 @default.
• W4315607762 cites W2517711526 @default.
• W4315607762 cites W2740883688 @default.
• W4315607762 cites W2914144156 @default.
• W4315607762 cites W2990543280 @default.
• W4315607762 cites W3035555096 @default.
• W4315607762 cites W3183163409 @default.
• W4315607762 cites W3191551713 @default.
• W4315607762 doi "https://doi.org/10.1016/j.ijantimicag.2023.106715" @default.
• W4315607762 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36640844" @default.
• W4315607762 hasPublicationYear "2023" @default.
• W4315607762 type Work @default.
• W4315607762 citedByCount "3" @default.
• W4315607762 countsByYear W43156077622023 @default.
• W4315607762 crossrefType "journal-article" @default.
• W4315607762 hasAuthorship W4315607762A5005968264 @default.
• W4315607762 hasAuthorship W4315607762A5006178415 @default.
• W4315607762 hasAuthorship W4315607762A5007337085 @default.
• W4315607762 hasAuthorship W4315607762A5008253667 @default.
• W4315607762 hasAuthorship W4315607762A5011980545 @default.
• W4315607762 hasAuthorship W4315607762A5015029026 @default.
• W4315607762 hasAuthorship W4315607762A5026585783 @default.
• W4315607762 hasAuthorship W4315607762A5028189683 @default.
• W4315607762 hasAuthorship W4315607762A5038030716 @default.
• W4315607762 hasAuthorship W4315607762A5045526607 @default.
• W4315607762 hasAuthorship W4315607762A5055502490 @default.
• W4315607762 hasAuthorship W4315607762A5058785356 @default.
• W4315607762 hasAuthorship W4315607762A5077775066 @default.
• W4315607762 hasAuthorship W4315607762A5084005100 @default.
• W4315607762 hasAuthorship W4315607762A5091307770 @default.
• W4315607762 hasConcept C203014093 @default.
• W4315607762 hasConcept C2776555147 @default.
• W4315607762 hasConcept C2777071850 @default.
• W4315607762 hasConcept C2778689377 @default.
• W4315607762 hasConcept C2779175654 @default.
• W4315607762 hasConcept C2779548794 @default.
• W4315607762 hasConcept C2779629538 @default.
• W4315607762 hasConcept C2780315139 @default.
• W4315607762 hasConcept C2780690907 @default.
• W4315607762 hasConcept C2781417161 @default.
• W4315607762 hasConcept C86803240 @default.
• W4315607762 hasConcept C89423630 @default.
• W4315607762 hasConceptScore W4315607762C203014093 @default.
• W4315607762 hasConceptScore W4315607762C2776555147 @default.
• W4315607762 hasConceptScore W4315607762C2777071850 @default.
• W4315607762 hasConceptScore W4315607762C2778689377 @default.
• W4315607762 hasConceptScore W4315607762C2779175654 @default.
• W4315607762 hasConceptScore W4315607762C2779548794 @default.
• W4315607762 hasConceptScore W4315607762C2779629538 @default.
• W4315607762 hasConceptScore W4315607762C2780315139 @default.
• W4315607762 hasConceptScore W4315607762C2780690907 @default.
• W4315607762 hasConceptScore W4315607762C2781417161 @default.
• W4315607762 hasConceptScore W4315607762C86803240 @default.
• W4315607762 hasConceptScore W4315607762C89423630 @default.
• W4315607762 hasFunder F4320322406 @default.
• W4315607762 hasIssue "3" @default.
• W4315607762 hasLocation W43156077621 @default.
• W4315607762 hasLocation W43156077622 @default.
• W4315607762 hasOpenAccess W4315607762 @default.
• W4315607762 hasPrimaryLocation W43156077621 @default.
• W4315607762 hasRelatedWork W1575274098 @default.
• W4315607762 hasRelatedWork W1925898314 @default.
• W4315607762 hasRelatedWork W1982026089 @default.
• W4315607762 hasRelatedWork W2008112150 @default.
• W4315607762 hasRelatedWork W2130173410 @default.
• W4315607762 hasRelatedWork W2134577373 @default.
• W4315607762 hasRelatedWork W2152477232 @default.
• W4315607762 hasRelatedWork W2364769236 @default.
• W4315607762 hasRelatedWork W2484496567 @default.

• next