Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315652681> ?p ?o ?g. }
- W4315652681 endingPage "123248" @default.
- W4315652681 startingPage "123248" @default.
- W4315652681 abstract "Gelatin hydrogel is widely employed in various fields, however, commercially available gelatin hydrogels are mostly derived from mammalian which has many disadvantages due to the supply and ethical issues. In this study, the properties of hydrogels from fish-derived collagen fabricated with varying Glutaraldehyde (GA) determined. The antidiabetic properties of salmon gelatin (SG) and tilapia gelatin (TG) was also evaluated against α-glucosidase. Glutaraldehyde-crosslinked salmon gelatin and tilapia gelatin were used, and compared with different concentrations of GA by 0.05 %, 0.1 %, and 0.15 %. Water absorbency, swelling, porosity, pore size and water retention of the hydrogels were dependent on the degree of crosslinking. The synthesis of hydrogels was confirmed by FTIR study. Scanning electron microscope (SEM) observation showed that all hydrogels have a porous structure with irregular shapes and heterogeneous morphology. Performance tests showed that gelatin-GA 0.05 % mixture had the best performance. Antidiabetic bioactivity in vitro and in silico tests showed that the active peptides of SG and TG showed a high binding affinity to α-glucosidase enzyme. In conclusion, SG and TG cross-linked GA 0.05 % have the potential as an antidiabetic agent and as a useful option over mammalian-derived gelatin." @default.
- W4315652681 created "2023-01-12" @default.
- W4315652681 creator A5003728669 @default.
- W4315652681 creator A5003996215 @default.
- W4315652681 creator A5005098719 @default.
- W4315652681 creator A5006663836 @default.
- W4315652681 creator A5029014226 @default.
- W4315652681 creator A5032426930 @default.
- W4315652681 creator A5034081477 @default.
- W4315652681 creator A5045691597 @default.
- W4315652681 creator A5052768964 @default.
- W4315652681 creator A5057732329 @default.
- W4315652681 creator A5070570476 @default.
- W4315652681 creator A5075139211 @default.
- W4315652681 creator A5088665720 @default.
- W4315652681 date "2023-03-01" @default.
- W4315652681 modified "2023-10-01" @default.
- W4315652681 title "Synthesis, modification and application of fish skin gelatin-based hydrogel as sustainable and versatile bioresource of antidiabetic peptide" @default.
- W4315652681 cites W1514754457 @default.
- W4315652681 cites W1762989988 @default.
- W4315652681 cites W1931365650 @default.
- W4315652681 cites W1990929635 @default.
- W4315652681 cites W2014274241 @default.
- W4315652681 cites W2015176909 @default.
- W4315652681 cites W2029561855 @default.
- W4315652681 cites W2082012892 @default.
- W4315652681 cites W2160544139 @default.
- W4315652681 cites W2161277086 @default.
- W4315652681 cites W2258451695 @default.
- W4315652681 cites W2336040088 @default.
- W4315652681 cites W2408188596 @default.
- W4315652681 cites W2519200619 @default.
- W4315652681 cites W2558620215 @default.
- W4315652681 cites W2593818584 @default.
- W4315652681 cites W2593974696 @default.
- W4315652681 cites W2605297265 @default.
- W4315652681 cites W2605330337 @default.
- W4315652681 cites W2611285098 @default.
- W4315652681 cites W2615590542 @default.
- W4315652681 cites W2618936805 @default.
- W4315652681 cites W2738539012 @default.
- W4315652681 cites W2754035247 @default.
- W4315652681 cites W2754543557 @default.
- W4315652681 cites W2767743278 @default.
- W4315652681 cites W2802017302 @default.
- W4315652681 cites W2846088788 @default.
- W4315652681 cites W2884019999 @default.
- W4315652681 cites W2885456592 @default.
- W4315652681 cites W2895986677 @default.
- W4315652681 cites W2906749379 @default.
- W4315652681 cites W2907348527 @default.
- W4315652681 cites W2911061271 @default.
- W4315652681 cites W2914710703 @default.
- W4315652681 cites W2940497578 @default.
- W4315652681 cites W2944453259 @default.
- W4315652681 cites W2978442985 @default.
- W4315652681 cites W2989663384 @default.
- W4315652681 cites W3003493035 @default.
- W4315652681 cites W3004075919 @default.
- W4315652681 cites W3004206814 @default.
- W4315652681 cites W3013316339 @default.
- W4315652681 cites W3013804926 @default.
- W4315652681 cites W3015463909 @default.
- W4315652681 cites W3026473302 @default.
- W4315652681 cites W3027571365 @default.
- W4315652681 cites W3031804782 @default.
- W4315652681 cites W3042531632 @default.
- W4315652681 cites W3049240982 @default.
- W4315652681 cites W3083146307 @default.
- W4315652681 cites W3093550202 @default.
- W4315652681 cites W3095641495 @default.
- W4315652681 cites W3114707268 @default.
- W4315652681 cites W3114937794 @default.
- W4315652681 cites W3116040071 @default.
- W4315652681 cites W3119210427 @default.
- W4315652681 cites W3123718834 @default.
- W4315652681 cites W3136770614 @default.
- W4315652681 cites W3153758208 @default.
- W4315652681 cites W3155062497 @default.
- W4315652681 cites W3161535006 @default.
- W4315652681 cites W3166474818 @default.
- W4315652681 cites W3170982515 @default.
- W4315652681 cites W3190348696 @default.
- W4315652681 cites W4285732024 @default.
- W4315652681 doi "https://doi.org/10.1016/j.ijbiomac.2023.123248" @default.
- W4315652681 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36642356" @default.
- W4315652681 hasPublicationYear "2023" @default.
- W4315652681 type Work @default.
- W4315652681 citedByCount "2" @default.
- W4315652681 countsByYear W43156526812023 @default.
- W4315652681 crossrefType "journal-article" @default.
- W4315652681 hasAuthorship W4315652681A5003728669 @default.
- W4315652681 hasAuthorship W4315652681A5003996215 @default.
- W4315652681 hasAuthorship W4315652681A5005098719 @default.
- W4315652681 hasAuthorship W4315652681A5006663836 @default.
- W4315652681 hasAuthorship W4315652681A5029014226 @default.
- W4315652681 hasAuthorship W4315652681A5032426930 @default.
- W4315652681 hasAuthorship W4315652681A5034081477 @default.