FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315702906> ?p ?o ?g. }

• W4315702906 endingPage "e294" @default.
• W4315702906 startingPage "e293" @default.
• W4315702906 abstract "Background: Since chronic kidney disease (CKD) is associated with the development of serious cardiovascular diseases such as stroke, coronary artery disease and heart failure, prevention and early diagnosis of CKD are important clinical issues. Many risk factors including diabetes, hypertension, dyslipidemia, obesity, and cigarette smoking are known to be involved in the development of CKD; however, there is no available biomarker that can predict the progression of CKD at an early stage. Although it has been reported that glomerular endothelial injury causes development of CKD, it remains unclear whether evaluation of vascular endothelial function can predict renal prognosis. Therefore, in the present study, we examined the association between vascular endothelial function and longitudinal eGFR change in patients with lifestyle-related diseases. Methods: We retrospectively evaluated 341 Japanese patients (176 males and 165 females; mean age, 63.87 ± 12.02 years) with lifestyle-related diseases in whom baseline vascular function was evaluated by flow-mediated dilation (FMD) and brachial-ankle pulse wave velocity (baPWV) and in whom 24-month longitudinal eGFR values were recorded after vascular testing at Tokushima University Hospital and Anan Medical Center, Tokushima Japan. The association between values of FMD and eGFR slope and the association between values of baPWV and eGFR slope were statistically analyzed. Statistical significance was set at p < 0.05. Results: Single regression analysis showed that value of FMD was positively associated with eGFR slope in females (p < 0.001) and non-smoking males (p = 0.033) but not in smoking males (p = 0.133). Multiple regression analysis including confounding factors demonstrated that the value of FMD remained a contributor against annual eGFR decline in females (p = 0.002) and non-smoking males (p = 0.046) but not in smoking males (p = 0.266). On the other hand, the value of baPWV had no significant association with eGFR slope regardless of sex and smoking. Conclusions: In patients with lifestyle-related diseases, FMD value can be used for prediction of renal prognosis represented by the eGFR slope in females and non-smoking males. Thus, early comprehensive intervention for improving vascular endothelial function might lead to a better renal prognosis in female and non-smoking male patients with lifestyle-related diseases." @default.
• W4315702906 created "2023-01-12" @default.
• W4315702906 creator A5000809053 @default.
• W4315702906 creator A5003558708 @default.
• W4315702906 creator A5027368074 @default.
• W4315702906 creator A5027751026 @default.
• W4315702906 creator A5030048295 @default.
• W4315702906 creator A5035678946 @default.
• W4315702906 creator A5037594625 @default.
• W4315702906 creator A5046968982 @default.
• W4315702906 creator A5048263730 @default.
• W4315702906 creator A5057452369 @default.
• W4315702906 creator A5059929150 @default.
• W4315702906 creator A5062973623 @default.
• W4315702906 creator A5086764205 @default.
• W4315702906 creator A5090993469 @default.
• W4315702906 date "2023-01-01" @default.
• W4315702906 modified "2023-10-02" @default.
• W4315702906 title "PS-BPC02-3: EVALUATION OF VASCULAR FUNCTION FOR PREDICTION OF RENAL PROGNOSIS IN JAPANESE PATIENTS WITH LIFESTYLE-RELATED DISEASES." @default.
• W4315702906 doi "https://doi.org/10.1097/01.hjh.0000915728.57423.79" @default.
• W4315702906 hasPublicationYear "2023" @default.
• W4315702906 type Work @default.
• W4315702906 citedByCount "0" @default.
• W4315702906 crossrefType "journal-article" @default.
• W4315702906 hasAuthorship W4315702906A5000809053 @default.
• W4315702906 hasAuthorship W4315702906A5003558708 @default.
• W4315702906 hasAuthorship W4315702906A5027368074 @default.
• W4315702906 hasAuthorship W4315702906A5027751026 @default.
• W4315702906 hasAuthorship W4315702906A5030048295 @default.
• W4315702906 hasAuthorship W4315702906A5035678946 @default.
• W4315702906 hasAuthorship W4315702906A5037594625 @default.
• W4315702906 hasAuthorship W4315702906A5046968982 @default.
• W4315702906 hasAuthorship W4315702906A5048263730 @default.
• W4315702906 hasAuthorship W4315702906A5057452369 @default.
• W4315702906 hasAuthorship W4315702906A5059929150 @default.
• W4315702906 hasAuthorship W4315702906A5062973623 @default.
• W4315702906 hasAuthorship W4315702906A5086764205 @default.
• W4315702906 hasAuthorship W4315702906A5090993469 @default.
• W4315702906 hasBestOaLocation W43157029061 @default.
• W4315702906 hasConcept C126322002 @default.
• W4315702906 hasConcept C134018914 @default.
• W4315702906 hasConcept C159641895 @default.
• W4315702906 hasConcept C164705383 @default.
• W4315702906 hasConcept C2777604165 @default.
• W4315702906 hasConcept C2778096610 @default.
• W4315702906 hasConcept C2778213512 @default.
• W4315702906 hasConcept C2778319312 @default.
• W4315702906 hasConcept C2778653478 @default.
• W4315702906 hasConcept C2779134260 @default.
• W4315702906 hasConcept C555293320 @default.
• W4315702906 hasConcept C71924100 @default.
• W4315702906 hasConcept C77350462 @default.
• W4315702906 hasConcept C84393581 @default.
• W4315702906 hasConceptScore W4315702906C126322002 @default.
• W4315702906 hasConceptScore W4315702906C134018914 @default.
• W4315702906 hasConceptScore W4315702906C159641895 @default.
• W4315702906 hasConceptScore W4315702906C164705383 @default.
• W4315702906 hasConceptScore W4315702906C2777604165 @default.
• W4315702906 hasConceptScore W4315702906C2778096610 @default.
• W4315702906 hasConceptScore W4315702906C2778213512 @default.
• W4315702906 hasConceptScore W4315702906C2778319312 @default.
• W4315702906 hasConceptScore W4315702906C2778653478 @default.
• W4315702906 hasConceptScore W4315702906C2779134260 @default.
• W4315702906 hasConceptScore W4315702906C555293320 @default.
• W4315702906 hasConceptScore W4315702906C71924100 @default.
• W4315702906 hasConceptScore W4315702906C77350462 @default.
• W4315702906 hasConceptScore W4315702906C84393581 @default.
• W4315702906 hasIssue "Suppl 1" @default.
• W4315702906 hasLocation W43157029061 @default.
• W4315702906 hasLocation W43157029062 @default.
• W4315702906 hasOpenAccess W4315702906 @default.
• W4315702906 hasPrimaryLocation W43157029061 @default.
• W4315702906 hasRelatedWork W2021055445 @default.
• W4315702906 hasRelatedWork W2078297210 @default.
• W4315702906 hasRelatedWork W2144543103 @default.
• W4315702906 hasRelatedWork W2347818059 @default.
• W4315702906 hasRelatedWork W2392216433 @default.
• W4315702906 hasRelatedWork W2413290422 @default.
• W4315702906 hasRelatedWork W3024677036 @default.
• W4315702906 hasRelatedWork W3112891903 @default.
• W4315702906 hasRelatedWork W4229452857 @default.
• W4315702906 hasRelatedWork W4386388733 @default.
• W4315702906 hasVolume "41" @default.
• W4315702906 isParatext "false" @default.
• W4315702906 isRetracted "false" @default.
• W4315702906 workType "article" @default.