Matches in SemOpenAlex for { <https://semopenalex.org/work/W4315705312> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4315705312 endingPage "e96" @default.
- W4315705312 startingPage "e96" @default.
- W4315705312 abstract "Background: Hypertension is a major risk factor for cardiovascular diseases and its prevalence among the Sub-Saharan African population has risen extremely in the last decades. Moreover, there is growing evidence that suggest that hypertension has its roots in childhood and adolescence and persist into adulthood. However, the epidemiology of hypertension in the young in a Low to Middle Income Country (LMIC) setting is not fully understood due to paucity of longitudinal data. Thus, we sought to investigate prevalence and new cases of hypertension and to identify risk factors that predict the incidence of hypertension from early childhood in urban black South-African children. Methods: We used data from the Birth to Twenty (BT20+) cohort in Johannesburg, South Africa. This cohort comprised of children born in 1990 and who had their growth, development and blood pressure measured at six follow-up periods over the course of 13 years. Hypertension status was classified using the fourth report of the National High Blood Pressure Education Program. Hypertension incidence rate was calculated using staggered entry survival analysis. We identified risk factors for incident hypertension using multivariable cox proportional hazard regressions. Results: Over a follow-up period of 13 years, the overall point prevalence of hypertension ranged from 8.4 to 24.4 % and cumulative incidence of hypertension was 54.3% (95% CI: 51.8 to 56.8). The overall hypertension incidence rate was 57.0 cases per 1000 person-years (95% CI: 53.2 to 61.1). Furthermore, the risk for incident hypertension increased with a rapid relative weight gain in early childhood (aHR = 1.11, 95% CI: 1.00 to 1.22), in mid childhood (aHR = 1.13, 95% CI: 1.03 to 1.24) and in adolescence (aHR = 1.21, 95% CI: 0.99 to 1.47). An increase in maternal parity significantly increased the risk for incident hypertension (aHR = 1.08, 95% CI: 1.01 to 1.15). Conclusion: Rapid weight gain relative to height and higher parity are prominent risk factors for incident hypertension in urban black South African children and adolescents. In order to reduce the high incidence and the disease burden of hypertension, national health programs should focus on promoting healthy lifestyle in early stages of life to curb rapid weight gain. Further research is required to check whether incident hypertension in childhood predict clinical outcomes in adulthood." @default.
- W4315705312 created "2023-01-12" @default.
- W4315705312 creator A5002775483 @default.
- W4315705312 creator A5059930390 @default.
- W4315705312 creator A5070509469 @default.
- W4315705312 creator A5074776547 @default.
- W4315705312 creator A5076996892 @default.
- W4315705312 date "2023-01-01" @default.
- W4315705312 modified "2023-10-02" @default.
- W4315705312 title "S-43-6: HYPERTENSION FROM CHILDHOOD TO ADULTHOOD: THE BT20+ STUDY" @default.
- W4315705312 doi "https://doi.org/10.1097/01.hjh.0000913664.62214.d4" @default.
- W4315705312 hasPublicationYear "2023" @default.
- W4315705312 type Work @default.
- W4315705312 citedByCount "0" @default.
- W4315705312 crossrefType "journal-article" @default.
- W4315705312 hasAuthorship W4315705312A5002775483 @default.
- W4315705312 hasAuthorship W4315705312A5059930390 @default.
- W4315705312 hasAuthorship W4315705312A5070509469 @default.
- W4315705312 hasAuthorship W4315705312A5074776547 @default.
- W4315705312 hasAuthorship W4315705312A5076996892 @default.
- W4315705312 hasBestOaLocation W43157053121 @default.
- W4315705312 hasConcept C107130276 @default.
- W4315705312 hasConcept C120665830 @default.
- W4315705312 hasConcept C121332964 @default.
- W4315705312 hasConcept C126322002 @default.
- W4315705312 hasConcept C144024400 @default.
- W4315705312 hasConcept C149923435 @default.
- W4315705312 hasConcept C187212893 @default.
- W4315705312 hasConcept C201903717 @default.
- W4315705312 hasConcept C207103383 @default.
- W4315705312 hasConcept C2908647359 @default.
- W4315705312 hasConcept C44249647 @default.
- W4315705312 hasConcept C50382708 @default.
- W4315705312 hasConcept C50440223 @default.
- W4315705312 hasConcept C61511704 @default.
- W4315705312 hasConcept C71924100 @default.
- W4315705312 hasConcept C72563966 @default.
- W4315705312 hasConcept C84393581 @default.
- W4315705312 hasConcept C88879693 @default.
- W4315705312 hasConcept C99454951 @default.
- W4315705312 hasConceptScore W4315705312C107130276 @default.
- W4315705312 hasConceptScore W4315705312C120665830 @default.
- W4315705312 hasConceptScore W4315705312C121332964 @default.
- W4315705312 hasConceptScore W4315705312C126322002 @default.
- W4315705312 hasConceptScore W4315705312C144024400 @default.
- W4315705312 hasConceptScore W4315705312C149923435 @default.
- W4315705312 hasConceptScore W4315705312C187212893 @default.
- W4315705312 hasConceptScore W4315705312C201903717 @default.
- W4315705312 hasConceptScore W4315705312C207103383 @default.
- W4315705312 hasConceptScore W4315705312C2908647359 @default.
- W4315705312 hasConceptScore W4315705312C44249647 @default.
- W4315705312 hasConceptScore W4315705312C50382708 @default.
- W4315705312 hasConceptScore W4315705312C50440223 @default.
- W4315705312 hasConceptScore W4315705312C61511704 @default.
- W4315705312 hasConceptScore W4315705312C71924100 @default.
- W4315705312 hasConceptScore W4315705312C72563966 @default.
- W4315705312 hasConceptScore W4315705312C84393581 @default.
- W4315705312 hasConceptScore W4315705312C88879693 @default.
- W4315705312 hasConceptScore W4315705312C99454951 @default.
- W4315705312 hasIssue "Suppl 1" @default.
- W4315705312 hasLocation W43157053121 @default.
- W4315705312 hasLocation W43157053122 @default.
- W4315705312 hasOpenAccess W4315705312 @default.
- W4315705312 hasPrimaryLocation W43157053121 @default.
- W4315705312 hasRelatedWork W1974042200 @default.
- W4315705312 hasRelatedWork W2001972347 @default.
- W4315705312 hasRelatedWork W2048418690 @default.
- W4315705312 hasRelatedWork W2060022074 @default.
- W4315705312 hasRelatedWork W2104371799 @default.
- W4315705312 hasRelatedWork W2147263480 @default.
- W4315705312 hasRelatedWork W2350777139 @default.
- W4315705312 hasRelatedWork W2909258897 @default.
- W4315705312 hasRelatedWork W2980864243 @default.
- W4315705312 hasRelatedWork W3110151069 @default.
- W4315705312 hasVolume "41" @default.
- W4315705312 isParatext "false" @default.
- W4315705312 isRetracted "false" @default.
- W4315705312 workType "article" @default.