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- W4315706945 abstract "Purposes: Central blood pressure is a stronger predictor of cardiovascular prognosis rather than brachial blood pressure. Reflection wave reaches abdominal aorta sooner than ascending aorta. Thus, the contribution of central pulse pressure (cPP) to renal events may differ from that to cardiovascular events. Methods: The sub-analysis of ABC-J II study was performed. Subjects were 3434 treated hypertensive patients with mean follow-up of 4.7 years. Left ventricular hypertrophy, an index of cardiovascular risk, correlated with cPP better than central systolic blood pressure in this cohort. The contribution of brachial pulse pressure (bPP) and cPP to cardiovascular and renal events were analyzed. Multivariate Cox regressions were performed by restricting independent variables according to the number of events. The independent variables, which were either significant in univariate Cox regression or of clinical interest, were applied. Results: Total of 63 cardiovascular and 34 renal events were occurred. Multivariate Cox proportional-hazard analysis revealed that sex (p < 0.001), height (p < 0.05), history of cardiovascular diseases (p < 0.001), numbers of antihypertensive drugs (p < 0.05) and cPP (p < 0.05) contributed to cardiovascular events (Table 1). However, multivariate Cox proportional-hazard analysis disclosed that baseline serum creatinine (p < 0.001) and bPP (p < 0.05) predicted renal events (Table 2). Conclusions: The present findings suggest that cPP and bPP contribute to cardiovascular and renal events in treated hypertensive patients." @default.
- W4315706945 created "2023-01-12" @default.
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- W4315706945 date "2023-01-01" @default.
- W4315706945 modified "2023-10-03" @default.
- W4315706945 title "PS-C07-1: CENTRAL AND BRACHIAL PULSE PRESSURE PREDICTS CARDIOVASCULAR AND RENAL EVENTS IN TREATED HYPERTENSIVE PATIENTS" @default.
- W4315706945 doi "https://doi.org/10.1097/01.hjh.0000914716.09799.ba" @default.
- W4315706945 hasPublicationYear "2023" @default.
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